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Gene Gene information from NCBI Gene database.
Entrez ID 80823
Gene name G protein-coupled receptor associated sorting protein family member 3
Gene symbol GPRASP3
Synonyms (NCBI Gene)
BHLHB9GASP3p60TRP
Chromosome X
Chromosome location Xq22.1
miRNA miRNA information provided by mirtarbase database.
244 Show/Hide all (244)
miRTarBase ID miRNA Experiments Reference
MIRT016652 hsa-miR-425-5p Sequencing 20371350
MIRT638959 hsa-miR-8485 HITS-CLIP 23824327
MIRT638958 hsa-miR-603 HITS-CLIP 23824327
MIRT638957 hsa-miR-4639-3p HITS-CLIP 23824327
MIRT638956 hsa-miR-342-3p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
18 Show/Hide all (18)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 32296183
GO:0005634 Component Nucleus IBA
GO:0005634 Component Nucleus IEA
GO:0005737 Component Cytoplasm IEA
GO:0005829 Component Cytosol IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
300921 29353 ENSG00000198908
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q6PI77
Protein name G protein-coupled receptor associated sorting protein 3 (Protein BHLHb9) (bHLHb9) (Transcription regulator of 60 kDa) (p60TRP)
Protein function Survival and differentiation promoting protein that plays a role in the regulation of neurosynaptogenesis. Induces phosphatase PP2A activity which results in APP dephosphorylation and inhibits BACE1-mediated processing of APP. {ECO:0000250|UniPr
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF04826 Arm_2 312 → 547 Armadillo-like Family
Tissue specificity TISSUE SPECIFICITY: Highly expressed in brain. Not expressed in lung or liver. Down-regulated in brain from patients suffering from Alzheimer disease. {ECO:0000269|PubMed:15034937}.
Sequence
MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA
VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATIN
SWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWE
GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE
ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIR
IREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEF
INEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSP
GQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARD
MINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREV
KEIIETM
Sequence length 547
Interactions View interactions