GPRASP3 (G protein-coupled receptor associated sorting protein family member 3)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 80823 |
| Gene name | G protein-coupled receptor associated sorting protein family member 3 |
| Gene symbol | GPRASP3 |
| Synonyms (NCBI Gene) |
BHLHB9GASP3p60TRP
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| Chromosome | X |
| Chromosome location | Xq22.1 |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q6PI77 | ||||||||||
| Protein name | G protein-coupled receptor associated sorting protein 3 (Protein BHLHb9) (bHLHb9) (Transcription regulator of 60 kDa) (p60TRP) | ||||||||||
| Protein function | Survival and differentiation promoting protein that plays a role in the regulation of neurosynaptogenesis. Induces phosphatase PP2A activity which results in APP dephosphorylation and inhibits BACE1-mediated processing of APP. {ECO:0000250|UniPr | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Highly expressed in brain. Not expressed in lung or liver. Down-regulated in brain from patients suffering from Alzheimer disease. {ECO:0000269|PubMed:15034937}. | ||||||||||
| Sequence |
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| Sequence length | 547 | ||||||||||
| Interactions | View interactions | ||||||||||
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Related Genes
Genes most often co-reported with GPRASP3 across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to GPRASP3 (see Related Genes above), that are NOT already directly curated for GPRASP3 itself -- a lead worth checking, not a confirmed association.
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