GPR22 (G protein-coupled receptor 22)

Download as csv Download as pdf

Log in to save this analysis

Save This Analysis

Title Project / Tag (optional) Note (optional)

Cancel Save

On this page

Gene miRNA Gene ontology Other IDs Protein Diseases linked via similar genes

Gene

• Entrez ID: 2845
• Gene name: G protein-coupled receptor 22
• Gene symbol: GPR22
• Synonyms (NCBI Gene): -
• Chromosome: 7
• Chromosome location: 7q22.3
• Summary: This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein. [provided by RefSeq, Jul 2008]

miRNA Show/Hide all (49)

miRTarBase ID	miRNA	Experiments	Reference
MIRT019001	hsa-miR-335-5p	Microarray	18185580
MIRT030206	hsa-miR-26b-5p	Microarray	19088304
MIRT1031176	hsa-miR-23a	CLIP-seq
MIRT1031177	hsa-miR-23b	CLIP-seq
MIRT1031178	hsa-miR-23c	CLIP-seq
MIRT1031179	hsa-miR-3065-5p	CLIP-seq
MIRT1031180	hsa-miR-3647-3p	CLIP-seq
MIRT1031181	hsa-miR-4282	CLIP-seq
MIRT1031182	hsa-miR-4659a-5p	CLIP-seq
MIRT1031183	hsa-miR-4659b-5p	CLIP-seq
MIRT1031184	hsa-miR-4769-3p	CLIP-seq
MIRT1031185	hsa-miR-4803	CLIP-seq
MIRT1031186	hsa-miR-495	CLIP-seq
MIRT2005882	hsa-miR-181a	CLIP-seq
MIRT2005883	hsa-miR-181b	CLIP-seq
MIRT2005884	hsa-miR-181c	CLIP-seq
MIRT2005885	hsa-miR-181d	CLIP-seq
MIRT1031176	hsa-miR-23a	CLIP-seq
MIRT1031177	hsa-miR-23b	CLIP-seq
MIRT1031178	hsa-miR-23c	CLIP-seq
MIRT2005886	hsa-miR-4262	CLIP-seq
MIRT2005887	hsa-miR-489	CLIP-seq
MIRT2238473	hsa-miR-1278	CLIP-seq
MIRT1031182	hsa-miR-4659a-5p	CLIP-seq
MIRT1031183	hsa-miR-4659b-5p	CLIP-seq
MIRT1031184	hsa-miR-4769-3p	CLIP-seq
MIRT1031186	hsa-miR-495	CLIP-seq
MIRT2005882	hsa-miR-181a	CLIP-seq
MIRT2005883	hsa-miR-181b	CLIP-seq
MIRT2005884	hsa-miR-181c	CLIP-seq
MIRT2005885	hsa-miR-181d	CLIP-seq
MIRT1031176	hsa-miR-23a	CLIP-seq
MIRT1031177	hsa-miR-23b	CLIP-seq
MIRT1031178	hsa-miR-23c	CLIP-seq
MIRT1031180	hsa-miR-3647-3p	CLIP-seq
MIRT2005886	hsa-miR-4262	CLIP-seq
MIRT2542454	hsa-miR-4735-5p	CLIP-seq
MIRT2005887	hsa-miR-489	CLIP-seq
MIRT2005882	hsa-miR-181a	CLIP-seq
MIRT2005883	hsa-miR-181b	CLIP-seq
MIRT2005884	hsa-miR-181c	CLIP-seq
MIRT2005885	hsa-miR-181d	CLIP-seq
MIRT1031176	hsa-miR-23a	CLIP-seq
MIRT1031177	hsa-miR-23b	CLIP-seq
MIRT1031178	hsa-miR-23c	CLIP-seq
MIRT1031180	hsa-miR-3647-3p	CLIP-seq
MIRT2005886	hsa-miR-4262	CLIP-seq
MIRT2542454	hsa-miR-4735-5p	CLIP-seq
MIRT2005887	hsa-miR-489	CLIP-seq

Gene ontology (GO) Show/Hide all (12)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004930	Function	G protein-coupled receptor activity	IBA
GO:0004930	Function	G protein-coupled receptor activity	IEA
GO:0004930	Function	G protein-coupled receptor activity	IMP	18539757
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	ISS
GO:0007165	Process	Signal transduction	IEA
GO:0007186	Process	G protein-coupled receptor signaling pathway	IBA
GO:0007186	Process	G protein-coupled receptor signaling pathway	IEA
GO:0016020	Component	Membrane	IEA
GO:0030030	Process	Cell projection organization	IEA
GO:0032870	Process	Cellular response to hormone stimulus	IBA

Other IDs

• MIM: 601910
• HGNC: 4477
• e!Ensembl: ENSG00000172209

Protein

• UniProt ID: Q99680
• Protein name: G-protein coupled receptor 22
• Protein function: Orphan G-protein coupled receptor. Seems to act through a G(i)/G(o) mediated pathway (PubMed:18539757). May be involved in ciliogenesis (By similarity).
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00001	7tm_1	58 → 367	7 transmembrane receptor (rhodopsin family)	Family

• Tissue specificity: TISSUE SPECIFICITY: High expression in adult and fetal heart tissue (PubMed:18539757). Expressed in the brain, with enrichment in the accumbens, amygdala, cerebellum, cortex, and hippocampus regions (PubMed:18539757, PubMed:9073069). {ECO:0000269|PubMed:1
• Sequence:

  MCFSPILEINMQSESNITVRDDIDDINTNMYQPLSYPLSFQVSLTGFLMLEIVLGLGSNL
  TVLVLYCMKSNLINSVSNIITMNLHVLDVIICVGCIPLTIVILLLSLESNTALICCFHEA
  CVSFASVSTAINVFAITLDRYDISVKPANRILTMGRAVMLMISIWIFSFFSFLIPFIEVN
  FFSLQSGNTWENKTLLCVSTNEYYTELGMYYHLLVQIPIFFFTVVVMLITYTKILQALNI
  RIGTRFSTGQKKKARKKKTISLTTQHEATDMSQSSGGRNVVFGVRTSVSVIIALRRAVKR
  HRERRERQKRVFRMSLLIISTFLLCWTPISVLNTTILCLGPSDLLVKLRLCFLVMAYGTT
  IFHPLLYAFTRQKFQKVLKSKMKKRVVSIVEADPLPNNAVIHNSWIDPKRNKKITFEDSE
  IREKCLVPQVVTD

• Sequence length: 433

Related Genes

No strongly related genes found yet for GPR22.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to GPR22.