GPR173 (G protein-coupled receptor 173)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 54328
• Gene name: G protein-coupled receptor 173
• Gene symbol: GPR173
• Synonyms (NCBI Gene): SREB3
• Chromosome: X
• Chromosome location: Xp11.22
• Summary: This gene encodes a member of the G-protein coupled receptor 1 family. This protein contains 7 transmembrane domains and conserved cysteine residues. [provided by RefSeq, Nov 2009]

miRNA Show/Hide all (212)

miRTarBase ID	miRNA	Experiments	Reference
MIRT682990	hsa-miR-4524a-3p	HITS-CLIP	23706177
MIRT611205	hsa-miR-8485	HITS-CLIP	23824327
MIRT611205	hsa-miR-8485	HITS-CLIP	23824327
MIRT611205	hsa-miR-8485	HITS-CLIP	23824327
MIRT611205	hsa-miR-8485	HITS-CLIP	23824327
MIRT630453	hsa-miR-4311	HITS-CLIP	23824327
MIRT611205	hsa-miR-8485	HITS-CLIP	23824327
MIRT611205	hsa-miR-8485	HITS-CLIP	23824327
MIRT611205	hsa-miR-8485	HITS-CLIP	23824327
MIRT611205	hsa-miR-8485	HITS-CLIP	23824327
MIRT611205	hsa-miR-8485	HITS-CLIP	23824327
MIRT611205	hsa-miR-8485	HITS-CLIP	23824327
MIRT569742	hsa-miR-5197-3p	PAR-CLIP	20371350
MIRT569740	hsa-miR-4463	PAR-CLIP	20371350
MIRT569741	hsa-miR-6760-5p	PAR-CLIP	20371350
MIRT569739	hsa-miR-1253	PAR-CLIP	20371350
MIRT569738	hsa-miR-873-3p	PAR-CLIP	20371350
MIRT569737	hsa-miR-4419a	PAR-CLIP	20371350
MIRT569736	hsa-miR-4510	PAR-CLIP	20371350
MIRT569735	hsa-miR-6127	PAR-CLIP	20371350
MIRT569734	hsa-miR-6129	PAR-CLIP	20371350
MIRT569733	hsa-miR-6130	PAR-CLIP	20371350
MIRT569732	hsa-miR-6133	PAR-CLIP	20371350
MIRT569731	hsa-miR-4434	PAR-CLIP	20371350
MIRT569730	hsa-miR-4516	PAR-CLIP	20371350
MIRT569729	hsa-miR-5703	PAR-CLIP	20371350
MIRT569728	hsa-miR-1249-5p	PAR-CLIP	20371350
MIRT569727	hsa-miR-6797-5p	PAR-CLIP	20371350
MIRT569725	hsa-miR-6878-5p	PAR-CLIP	20371350
MIRT569726	hsa-miR-149-3p	PAR-CLIP	20371350
MIRT569724	hsa-miR-4728-5p	PAR-CLIP	20371350
MIRT569723	hsa-miR-6785-5p	PAR-CLIP	20371350
MIRT569722	hsa-miR-6883-5p	PAR-CLIP	20371350
MIRT569721	hsa-miR-3175	PAR-CLIP	20371350
MIRT569720	hsa-miR-1343-5p	PAR-CLIP	20371350
MIRT569719	hsa-miR-939-5p	PAR-CLIP	20371350
MIRT569718	hsa-miR-6825-5p	PAR-CLIP	20371350
MIRT569717	hsa-miR-541-3p	PAR-CLIP	20371350
MIRT569716	hsa-miR-654-5p	PAR-CLIP	20371350
MIRT569715	hsa-miR-92a-2-5p	PAR-CLIP	20371350
MIRT569714	hsa-miR-6769a-5p	PAR-CLIP	20371350
MIRT569713	hsa-miR-6769b-5p	PAR-CLIP	20371350
MIRT569712	hsa-miR-491-5p	PAR-CLIP	20371350
MIRT569711	hsa-miR-3150a-3p	PAR-CLIP	20371350
MIRT569710	hsa-miR-6763-5p	PAR-CLIP	20371350
MIRT569709	hsa-miR-3202	PAR-CLIP	20371350
MIRT529863	hsa-miR-586	PAR-CLIP	22012620
MIRT529861	hsa-miR-6767-3p	PAR-CLIP	22012620
MIRT529860	hsa-miR-223-5p	PAR-CLIP	22012620
MIRT529859	hsa-miR-6867-5p	PAR-CLIP	22012620
MIRT529858	hsa-miR-675-3p	PAR-CLIP	22012620
MIRT529857	hsa-miR-574-5p	PAR-CLIP	22012620
MIRT682990	hsa-miR-4524a-3p	PAR-CLIP	27292025
MIRT682990	hsa-miR-4524a-3p	PAR-CLIP	27292025
MIRT682990	hsa-miR-4524a-3p	HITS-CLIP	23706177
MIRT611205	hsa-miR-8485	HITS-CLIP	23824327
MIRT611205	hsa-miR-8485	HITS-CLIP	23824327
MIRT611205	hsa-miR-8485	HITS-CLIP	23824327
MIRT611205	hsa-miR-8485	HITS-CLIP	23824327
MIRT630453	hsa-miR-4311	HITS-CLIP	23824327
MIRT611205	hsa-miR-8485	HITS-CLIP	23824327
MIRT611205	hsa-miR-8485	HITS-CLIP	23824327
MIRT611205	hsa-miR-8485	HITS-CLIP	23824327
MIRT611205	hsa-miR-8485	HITS-CLIP	23824327
MIRT611205	hsa-miR-8485	HITS-CLIP	23824327
MIRT611205	hsa-miR-8485	HITS-CLIP	23824327
MIRT569742	hsa-miR-5197-3p	PAR-CLIP	20371350
MIRT569740	hsa-miR-4463	PAR-CLIP	20371350
MIRT569741	hsa-miR-6760-5p	PAR-CLIP	20371350
MIRT569739	hsa-miR-1253	PAR-CLIP	20371350
MIRT569738	hsa-miR-873-3p	PAR-CLIP	20371350
MIRT569737	hsa-miR-4419a	PAR-CLIP	20371350
MIRT569736	hsa-miR-4510	PAR-CLIP	20371350
MIRT569735	hsa-miR-6127	PAR-CLIP	20371350
MIRT569734	hsa-miR-6129	PAR-CLIP	20371350
MIRT569733	hsa-miR-6130	PAR-CLIP	20371350
MIRT569732	hsa-miR-6133	PAR-CLIP	20371350
MIRT569731	hsa-miR-4434	PAR-CLIP	20371350
MIRT569730	hsa-miR-4516	PAR-CLIP	20371350
MIRT569729	hsa-miR-5703	PAR-CLIP	20371350
MIRT569728	hsa-miR-1249-5p	PAR-CLIP	20371350
MIRT569727	hsa-miR-6797-5p	PAR-CLIP	20371350
MIRT569725	hsa-miR-6878-5p	PAR-CLIP	20371350
MIRT569726	hsa-miR-149-3p	PAR-CLIP	20371350
MIRT569724	hsa-miR-4728-5p	PAR-CLIP	20371350
MIRT569723	hsa-miR-6785-5p	PAR-CLIP	20371350
MIRT569722	hsa-miR-6883-5p	PAR-CLIP	20371350
MIRT569721	hsa-miR-3175	PAR-CLIP	20371350
MIRT569720	hsa-miR-1343-5p	PAR-CLIP	20371350
MIRT569719	hsa-miR-939-5p	PAR-CLIP	20371350
MIRT569718	hsa-miR-6825-5p	PAR-CLIP	20371350
MIRT569717	hsa-miR-541-3p	PAR-CLIP	20371350
MIRT569716	hsa-miR-654-5p	PAR-CLIP	20371350
MIRT569715	hsa-miR-92a-2-5p	PAR-CLIP	20371350
MIRT569714	hsa-miR-6769a-5p	PAR-CLIP	20371350
MIRT569713	hsa-miR-6769b-5p	PAR-CLIP	20371350
MIRT569712	hsa-miR-491-5p	PAR-CLIP	20371350
MIRT569711	hsa-miR-3150a-3p	PAR-CLIP	20371350
MIRT569710	hsa-miR-6763-5p	PAR-CLIP	20371350
MIRT569709	hsa-miR-3202	PAR-CLIP	20371350
MIRT529863	hsa-miR-586	PAR-CLIP	22012620
MIRT529861	hsa-miR-6767-3p	PAR-CLIP	22012620
MIRT529860	hsa-miR-223-5p	PAR-CLIP	22012620
MIRT529859	hsa-miR-6867-5p	PAR-CLIP	22012620
MIRT529858	hsa-miR-675-3p	PAR-CLIP	22012620
MIRT529857	hsa-miR-574-5p	PAR-CLIP	22012620
MIRT1030919	hsa-miR-219-2-3p	CLIP-seq
MIRT1030920	hsa-miR-2355-5p	CLIP-seq
MIRT1030921	hsa-miR-2964a-3p	CLIP-seq
MIRT1030922	hsa-miR-3123	CLIP-seq
MIRT1030923	hsa-miR-3155	CLIP-seq
MIRT1030924	hsa-miR-3155b	CLIP-seq
MIRT1030925	hsa-miR-3157-5p	CLIP-seq
MIRT1030926	hsa-miR-3173-3p	CLIP-seq
MIRT1030927	hsa-miR-3184	CLIP-seq
MIRT1030928	hsa-miR-3664-5p	CLIP-seq
MIRT1030929	hsa-miR-3679-3p	CLIP-seq
MIRT1030930	hsa-miR-378g	CLIP-seq
MIRT1030931	hsa-miR-3913-3p	CLIP-seq
MIRT1030932	hsa-miR-3925-5p	CLIP-seq
MIRT1030933	hsa-miR-423-5p	CLIP-seq
MIRT1030934	hsa-miR-4267	CLIP-seq
MIRT1030935	hsa-miR-4427	CLIP-seq
MIRT1030936	hsa-miR-4428	CLIP-seq
MIRT1030937	hsa-miR-4433	CLIP-seq
MIRT1030938	hsa-miR-4438	CLIP-seq
MIRT1030939	hsa-miR-4446-5p	CLIP-seq
MIRT1030940	hsa-miR-4459	CLIP-seq
MIRT1030941	hsa-miR-4514	CLIP-seq
MIRT1030942	hsa-miR-4521	CLIP-seq
MIRT1030943	hsa-miR-4645-5p	CLIP-seq
MIRT1030944	hsa-miR-4659a-3p	CLIP-seq
MIRT1030945	hsa-miR-4659b-3p	CLIP-seq
MIRT1030946	hsa-miR-4668-3p	CLIP-seq
MIRT1030947	hsa-miR-4673	CLIP-seq
MIRT1030948	hsa-miR-4680-3p	CLIP-seq
MIRT1030949	hsa-miR-4691-3p	CLIP-seq
MIRT1030950	hsa-miR-4692	CLIP-seq
MIRT1030951	hsa-miR-4714-5p	CLIP-seq
MIRT1030952	hsa-miR-4762-3p	CLIP-seq
MIRT1030953	hsa-miR-4768-3p	CLIP-seq
MIRT1030954	hsa-miR-4773	CLIP-seq
MIRT1030955	hsa-miR-4779	CLIP-seq
MIRT1030956	hsa-miR-484	CLIP-seq
MIRT1030957	hsa-miR-489	CLIP-seq
MIRT1030958	hsa-miR-515-3p	CLIP-seq
MIRT1030959	hsa-miR-519e	CLIP-seq
MIRT1030960	hsa-miR-520d-5p	CLIP-seq
MIRT1030961	hsa-miR-524-5p	CLIP-seq
MIRT1030962	hsa-miR-593	CLIP-seq
MIRT1030963	hsa-miR-629	CLIP-seq
MIRT1030964	hsa-miR-668	CLIP-seq
MIRT1030965	hsa-miR-939	CLIP-seq
MIRT2005834	hsa-miR-2467-3p	CLIP-seq
MIRT2005835	hsa-miR-3120-3p	CLIP-seq
MIRT1030922	hsa-miR-3123	CLIP-seq
MIRT2005836	hsa-miR-3124-3p	CLIP-seq
MIRT1030923	hsa-miR-3155	CLIP-seq
MIRT1030924	hsa-miR-3155b	CLIP-seq
MIRT2005837	hsa-miR-3189-3p	CLIP-seq
MIRT2005838	hsa-miR-362-5p	CLIP-seq
MIRT2005839	hsa-miR-3714	CLIP-seq
MIRT2005840	hsa-miR-4302	CLIP-seq
MIRT2005841	hsa-miR-4468	CLIP-seq
MIRT2005842	hsa-miR-4493	CLIP-seq
MIRT1030956	hsa-miR-484	CLIP-seq
MIRT2005843	hsa-miR-500b	CLIP-seq
MIRT2005844	hsa-miR-541	CLIP-seq
MIRT2005845	hsa-miR-617	CLIP-seq
MIRT2005846	hsa-miR-885-3p	CLIP-seq
MIRT1030965	hsa-miR-939	CLIP-seq
MIRT2238431	hsa-miR-1266	CLIP-seq
MIRT2238432	hsa-miR-224	CLIP-seq
MIRT2238433	hsa-miR-24	CLIP-seq
MIRT2238434	hsa-miR-3127-5p	CLIP-seq
MIRT2238435	hsa-miR-3140-5p	CLIP-seq
MIRT2005839	hsa-miR-3714	CLIP-seq
MIRT2238436	hsa-miR-377	CLIP-seq
MIRT2238437	hsa-miR-3918	CLIP-seq
MIRT2238438	hsa-miR-4283	CLIP-seq
MIRT2238439	hsa-miR-4489	CLIP-seq
MIRT2238440	hsa-miR-4492	CLIP-seq
MIRT2005842	hsa-miR-4493	CLIP-seq
MIRT2238441	hsa-miR-4498	CLIP-seq
MIRT2238442	hsa-miR-4512	CLIP-seq
MIRT2238443	hsa-miR-4518	CLIP-seq
MIRT2238444	hsa-miR-603	CLIP-seq
MIRT2238445	hsa-miR-762	CLIP-seq
MIRT2005846	hsa-miR-885-3p	CLIP-seq
MIRT2388634	hsa-miR-296-5p	CLIP-seq
MIRT2388635	hsa-miR-3162-3p	CLIP-seq
MIRT2388636	hsa-miR-4287	CLIP-seq
MIRT2388637	hsa-miR-4328	CLIP-seq
MIRT2388638	hsa-miR-4685-3p	CLIP-seq
MIRT1030954	hsa-miR-4773	CLIP-seq
MIRT2388639	hsa-miR-4780	CLIP-seq
MIRT2388640	hsa-miR-623	CLIP-seq
MIRT1030927	hsa-miR-3184	CLIP-seq
MIRT1030933	hsa-miR-423-5p	CLIP-seq
MIRT2450624	hsa-miR-4716-3p	CLIP-seq
MIRT2450625	hsa-miR-583	CLIP-seq
MIRT1030927	hsa-miR-3184	CLIP-seq
MIRT2465384	hsa-miR-320a	CLIP-seq
MIRT2465385	hsa-miR-320b	CLIP-seq
MIRT2465386	hsa-miR-320c	CLIP-seq
MIRT2465387	hsa-miR-320d	CLIP-seq
MIRT2465388	hsa-miR-330-3p	CLIP-seq
MIRT1030933	hsa-miR-423-5p	CLIP-seq
MIRT2465389	hsa-miR-4429	CLIP-seq
MIRT2450624	hsa-miR-4716-3p	CLIP-seq
MIRT2450625	hsa-miR-583	CLIP-seq
MIRT2682048	hsa-miR-1324	CLIP-seq

Gene ontology (GO) Show/Hide all (13)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004930	Function	G protein-coupled receptor activity	IEA
GO:0004930	Function	G protein-coupled receptor activity	TAS	10833454
GO:0004968	Function	Gonadotropin-releasing hormone receptor activity	IBA
GO:0004968	Function	Gonadotropin-releasing hormone receptor activity	IEA
GO:0005515	Function	Protein binding	IPI	28514442, 33961781
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0007165	Process	Signal transduction	IEA
GO:0007165	Process	Signal transduction	TAS	10833454
GO:0007186	Process	G protein-coupled receptor signaling pathway	IEA
GO:0016020	Component	Membrane	IEA
GO:0097211	Process	Cellular response to gonadotropin-releasing hormone	IEA
GO:2001223	Process	Negative regulation of neuron migration	IEA

Other IDs

• MIM: 300253
• HGNC: 18186
• e!Ensembl: ENSG00000184194

Protein

• UniProt ID: Q9NS66
• Protein name: Probable G-protein coupled receptor 173 (Super conserved receptor expressed in brain 3)
• Protein function: Is a receptor for the SMIM20 derived peptides Phoenixin-14 and Phoenixin-20 (By similarity). It mediates the Phoenixin-14 and Phoenixin-20 augmentation of gonadotropin-releasing hormone (GNRH) signaling in the hypothalamus and pituitary gland (B
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00001	7tm_1	39 → 340	7 transmembrane receptor (rhodopsin family)	Family

• Tissue specificity: TISSUE SPECIFICITY: Expressed in the ovary, specifically in granulosa cells of follicles that have passed the primary stage and in oocytes (at protein level) (PubMed:30933929). Expressed at high levels in brain. Lower levels in small intestine. In brain r
• Sequence:

  MANTTGEPEEVSGALSPPSASAYVKLVLLGLIMCVSLAGNAILSLLVLKERALHKAPYYF
  LLDLCLADGIRSAVCFPFVLASVRHGSSWTFSALSCKIVAFMAVLFCFHAAFMLFCISVT
  RYMAIAHHRFYAKRMTLWTCAAVICMAWTLSVAMAFPPVFDVGTYKFIREEDQCIFEHRY
  FKANDTLGFMLMLAVLMAATHAVYGKLLLFEYRHRKMKPVQMVPAISQNWTFHGPGATGQ
  AAANWIAGFGRGPMPPTLLGIRQNGHAASRRLLGMDEVKGEKQLGRMFYAITLLFLLLWS
  PYIVACYWRVFVKACAVPHRYLATAVWMSFAQAAVNPIVCFLLNKDLKKCLRTHAPCWGT
  GGAPAPREPYCVM

• Sequence length: 373

Related Genes

No strongly related genes found yet for GPR173.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to GPR173.