GPR108 (G protein-coupled receptor 108)

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Gene miRNA Gene ontology Other IDs Protein Diseases linked via similar genes

Gene

• Entrez ID: 56927
• Gene name: G protein-coupled receptor 108
• Gene symbol: GPR108
• Synonyms (NCBI Gene): LUSTR2
• Chromosome: 19
• Chromosome location: 19p13.3

miRNA Show/Hide all (29)

miRTarBase ID	miRNA	Experiments	Reference
MIRT018867	hsa-miR-335-5p	Microarray	18185580
MIRT045380	hsa-miR-185-5p	CLASH	23622248
MIRT1029861	hsa-miR-3154	CLIP-seq
MIRT1029862	hsa-miR-3178	CLIP-seq
MIRT1029863	hsa-miR-3185	CLIP-seq
MIRT1029864	hsa-miR-3190	CLIP-seq
MIRT1029865	hsa-miR-4281	CLIP-seq
MIRT1029866	hsa-miR-4286	CLIP-seq
MIRT1029867	hsa-miR-4300	CLIP-seq
MIRT1029868	hsa-miR-4449	CLIP-seq
MIRT1029869	hsa-miR-4486	CLIP-seq
MIRT1029870	hsa-miR-4487	CLIP-seq
MIRT1029871	hsa-miR-4497	CLIP-seq
MIRT1029872	hsa-miR-4532	CLIP-seq
MIRT1029873	hsa-miR-4640-3p	CLIP-seq
MIRT1029874	hsa-miR-4655-5p	CLIP-seq
MIRT1029875	hsa-miR-4717-3p	CLIP-seq
MIRT1029876	hsa-miR-4802-3p	CLIP-seq
MIRT1029877	hsa-miR-566	CLIP-seq
MIRT1029878	hsa-miR-615-5p	CLIP-seq
MIRT1029879	hsa-miR-7	CLIP-seq
MIRT1029880	hsa-miR-711	CLIP-seq
MIRT1029881	hsa-miR-920	CLIP-seq
MIRT1029882	hsa-miR-939	CLIP-seq
MIRT1029865	hsa-miR-4281	CLIP-seq
MIRT1029868	hsa-miR-4449	CLIP-seq
MIRT2005619	hsa-miR-4475	CLIP-seq
MIRT1029872	hsa-miR-4532	CLIP-seq
MIRT2238249	hsa-miR-4258	CLIP-seq

Gene ontology (GO) Show/Hide all (18)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005794	Component	Golgi apparatus	IBA
GO:0005794	Component	Golgi apparatus	IDA	32280726
GO:0005794	Component	Golgi apparatus	IEA
GO:0005794	Component	Golgi apparatus	IEA
GO:0005802	Component	Trans-Golgi network	IDA	31784416
GO:0016020	Component	Membrane	IBA
GO:0016020	Component	Membrane	IEA
GO:0033106	Component	Cis-Golgi network membrane	IEA
GO:0033106	Component	Cis-Golgi network membrane	ISS
GO:0034122	Process	Negative regulation of toll-like receptor signaling pathway	IBA
GO:0034122	Process	Negative regulation of toll-like receptor signaling pathway	IEA
GO:0034122	Process	Negative regulation of toll-like receptor signaling pathway	ISS
GO:0050776	Process	Regulation of immune response	IEA
GO:0050776	Process	Regulation of immune response	ISS
GO:0051607	Process	Defense response to virus	IEA
GO:0060337	Process	Type I interferon-mediated signaling pathway	IEA

Other IDs

• MIM: 618491
• HGNC: 17829
• e!Ensembl: ENSG00000125734

Protein

• UniProt ID: Q9NPR9
• Protein name: Protein GPR108 (Lung seven transmembrane receptor 2)
• Protein function: May play a role in intracellular immune modulation by activating NF-kappaB response and attenuating Toll-like-receptor response. ; (Microbial infection) Plays an essential function in adeno-associated vir
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF06814	Lung_7-TM_R	214 → 503	Lung seven transmembrane receptor	Family

• Sequence:

  MAVSERRGLGRGSPAEWGQRLLLVLLLGGCSGRIHQLALTGEKRADIQLNSFGFYTNGSL
  EVELSVLRLGLREAEEKSLLVGFSLSRVRSGRVRSYSTRDFQDCPLQKNSSSFLVLFLIN
  TKDLQVQVRKYGEQKTLFIFPGLLPEAPSKPGLPKPQATVPRKVDGGGTSAASKPKSTPA
  VIQGPSGKDKDLVLGLSHLNNSYNFSFHVVIGSQAEEGQYSLNFHNCNNSVPGKEHPFDI
  TVMIREKNPDGFLSAAEMPLFKLYMVMSACFLAAGIFWVSILCRNTYSVFKIHWLMAALA
  FTKSISLLFHSINYYFINSQGHPIEGLAVMYYIAHLLKGALLFITIALIGSGWAFIKYVL
  SDKEKKVFGIVIPMQVLANVAYIIIESREEGASDYVLWKEILFLVDLICCGAILFPVVWS
  IRHLQDASGTDGKVAVNLAKLKLFRHYYVMVICYVYFTRIIAILLQVAVPFQWQWLYQLL
  VEGSTLAFFVLTGYKFQPTGNNPYLQLPQEDEEDVQMEQVMTDSGFREGLSKVNKTASGR
  ELL

• Sequence length: 543

Related Genes

No strongly related genes found yet for GPR108.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to GPR108.