GLOD4 (glyoxalase domain containing 4)

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Gene miRNA Gene ontology Other IDs Protein Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 51031
• Gene name: Glyoxalase domain containing 4
• Gene symbol: GLOD4
• Synonyms (NCBI Gene): C17orf25, CGI-150, HC6, HC71
• Chromosome: 17
• Chromosome location: 17p13.3

miRNA Show/Hide all (223)

miRTarBase ID	miRNA	Experiments	Reference
MIRT023226	hsa-miR-122-5p	Proteomics	21750653
MIRT049198	hsa-miR-92a-3p	CLASH	23622248
MIRT047694	hsa-miR-10a-5p	CLASH	23622248
MIRT047475	hsa-miR-10b-5p	CLASH	23622248
MIRT040722	hsa-miR-92b-3p	CLASH	23622248
MIRT1021347	hsa-miR-1285	CLIP-seq
MIRT1021348	hsa-miR-1972	CLIP-seq
MIRT1021349	hsa-miR-214	CLIP-seq
MIRT1021350	hsa-miR-3120-3p	CLIP-seq
MIRT1021351	hsa-miR-3187-5p	CLIP-seq
MIRT1021352	hsa-miR-3619-5p	CLIP-seq
MIRT1021353	hsa-miR-3935	CLIP-seq
MIRT1021354	hsa-miR-4280	CLIP-seq
MIRT1021355	hsa-miR-4462	CLIP-seq
MIRT1021356	hsa-miR-4650-5p	CLIP-seq
MIRT1021357	hsa-miR-4709-5p	CLIP-seq
MIRT1021358	hsa-miR-4731-5p	CLIP-seq
MIRT1021359	hsa-miR-513a-5p	CLIP-seq
MIRT1021360	hsa-miR-552	CLIP-seq
MIRT1021361	hsa-miR-612	CLIP-seq
MIRT1021362	hsa-miR-668	CLIP-seq
MIRT1021363	hsa-miR-761	CLIP-seq
MIRT1021364	hsa-miR-764	CLIP-seq
MIRT1021347	hsa-miR-1285	CLIP-seq
MIRT1021351	hsa-miR-3187-5p	CLIP-seq
MIRT1021358	hsa-miR-4731-5p	CLIP-seq
MIRT1021361	hsa-miR-612	CLIP-seq
MIRT1021347	hsa-miR-1285	CLIP-seq
MIRT2002610	hsa-miR-1293	CLIP-seq
MIRT1021348	hsa-miR-1972	CLIP-seq
MIRT2002611	hsa-miR-203	CLIP-seq
MIRT1021349	hsa-miR-214	CLIP-seq
MIRT1021350	hsa-miR-3120-3p	CLIP-seq
MIRT2002612	hsa-miR-3130-3p	CLIP-seq
MIRT1021351	hsa-miR-3187-5p	CLIP-seq
MIRT2002613	hsa-miR-3188	CLIP-seq
MIRT2002614	hsa-miR-3194-3p	CLIP-seq
MIRT1021352	hsa-miR-3619-5p	CLIP-seq
MIRT2002615	hsa-miR-371b-5p	CLIP-seq
MIRT2002616	hsa-miR-3910	CLIP-seq
MIRT1021353	hsa-miR-3935	CLIP-seq
MIRT1021354	hsa-miR-4280	CLIP-seq
MIRT1021355	hsa-miR-4462	CLIP-seq
MIRT2002617	hsa-miR-4483	CLIP-seq
MIRT2002618	hsa-miR-4491	CLIP-seq
MIRT1021356	hsa-miR-4650-5p	CLIP-seq
MIRT2002619	hsa-miR-4651	CLIP-seq
MIRT2002620	hsa-miR-4657	CLIP-seq
MIRT2002621	hsa-miR-4690-5p	CLIP-seq
MIRT2002622	hsa-miR-4698	CLIP-seq
MIRT1021357	hsa-miR-4709-5p	CLIP-seq
MIRT2002623	hsa-miR-4711-5p	CLIP-seq
MIRT2002624	hsa-miR-4719	CLIP-seq
MIRT2002625	hsa-miR-4731-3p	CLIP-seq
MIRT1021358	hsa-miR-4731-5p	CLIP-seq
MIRT2002626	hsa-miR-4733-5p	CLIP-seq
MIRT2002627	hsa-miR-4762-5p	CLIP-seq
MIRT2002628	hsa-miR-4793-3p	CLIP-seq
MIRT2002629	hsa-miR-4801	CLIP-seq
MIRT1021359	hsa-miR-513a-5p	CLIP-seq
MIRT1021360	hsa-miR-552	CLIP-seq
MIRT2002630	hsa-miR-608	CLIP-seq
MIRT1021361	hsa-miR-612	CLIP-seq
MIRT1021362	hsa-miR-668	CLIP-seq
MIRT1021363	hsa-miR-761	CLIP-seq
MIRT1021364	hsa-miR-764	CLIP-seq
MIRT2002631	hsa-miR-876-3p	CLIP-seq
MIRT2002632	hsa-miR-888	CLIP-seq
MIRT1021347	hsa-miR-1285	CLIP-seq
MIRT1021348	hsa-miR-1972	CLIP-seq
MIRT2235589	hsa-miR-2117	CLIP-seq
MIRT1021349	hsa-miR-214	CLIP-seq
MIRT1021350	hsa-miR-3120-3p	CLIP-seq
MIRT1021351	hsa-miR-3187-5p	CLIP-seq
MIRT2002613	hsa-miR-3188	CLIP-seq
MIRT2002614	hsa-miR-3194-3p	CLIP-seq
MIRT2235590	hsa-miR-3614-5p	CLIP-seq
MIRT1021352	hsa-miR-3619-5p	CLIP-seq
MIRT2235591	hsa-miR-3690	CLIP-seq
MIRT2235592	hsa-miR-3691-5p	CLIP-seq
MIRT2235593	hsa-miR-378	CLIP-seq
MIRT2235594	hsa-miR-378b	CLIP-seq
MIRT2235595	hsa-miR-378c	CLIP-seq
MIRT2235596	hsa-miR-378d	CLIP-seq
MIRT2235597	hsa-miR-378e	CLIP-seq
MIRT2235598	hsa-miR-378f	CLIP-seq
MIRT2235599	hsa-miR-378h	CLIP-seq
MIRT2235600	hsa-miR-378i	CLIP-seq
MIRT2002616	hsa-miR-3910	CLIP-seq
MIRT1021353	hsa-miR-3935	CLIP-seq
MIRT2235601	hsa-miR-422a	CLIP-seq
MIRT2235602	hsa-miR-4257	CLIP-seq
MIRT1021354	hsa-miR-4280	CLIP-seq
MIRT2235603	hsa-miR-4320	CLIP-seq
MIRT2235604	hsa-miR-433	CLIP-seq
MIRT1021355	hsa-miR-4462	CLIP-seq
MIRT2235605	hsa-miR-4471	CLIP-seq
MIRT2002618	hsa-miR-4491	CLIP-seq
MIRT2235606	hsa-miR-4638-3p	CLIP-seq
MIRT1021356	hsa-miR-4650-5p	CLIP-seq
MIRT2002620	hsa-miR-4657	CLIP-seq
MIRT2235607	hsa-miR-4684-5p	CLIP-seq
MIRT2002621	hsa-miR-4690-5p	CLIP-seq
MIRT1021357	hsa-miR-4709-5p	CLIP-seq
MIRT2002623	hsa-miR-4711-5p	CLIP-seq
MIRT2235608	hsa-miR-4729	CLIP-seq
MIRT1021358	hsa-miR-4731-5p	CLIP-seq
MIRT2002626	hsa-miR-4733-5p	CLIP-seq
MIRT2235609	hsa-miR-4752	CLIP-seq
MIRT1021359	hsa-miR-513a-5p	CLIP-seq
MIRT1021360	hsa-miR-552	CLIP-seq
MIRT1021361	hsa-miR-612	CLIP-seq
MIRT2235610	hsa-miR-619	CLIP-seq
MIRT1021362	hsa-miR-668	CLIP-seq
MIRT2235611	hsa-miR-676	CLIP-seq
MIRT1021363	hsa-miR-761	CLIP-seq
MIRT1021364	hsa-miR-764	CLIP-seq
MIRT2539487	hsa-miR-1206	CLIP-seq
MIRT1021347	hsa-miR-1285	CLIP-seq
MIRT2539488	hsa-miR-1305	CLIP-seq
MIRT2539489	hsa-miR-1323	CLIP-seq
MIRT1021348	hsa-miR-1972	CLIP-seq
MIRT2235589	hsa-miR-2117	CLIP-seq
MIRT1021349	hsa-miR-214	CLIP-seq
MIRT1021350	hsa-miR-3120-3p	CLIP-seq
MIRT1021351	hsa-miR-3187-5p	CLIP-seq
MIRT2002613	hsa-miR-3188	CLIP-seq
MIRT2002614	hsa-miR-3194-3p	CLIP-seq
MIRT2235590	hsa-miR-3614-5p	CLIP-seq
MIRT1021352	hsa-miR-3619-5p	CLIP-seq
MIRT2235591	hsa-miR-3690	CLIP-seq
MIRT2235592	hsa-miR-3691-5p	CLIP-seq
MIRT2235593	hsa-miR-378	CLIP-seq
MIRT2235594	hsa-miR-378b	CLIP-seq
MIRT2235595	hsa-miR-378c	CLIP-seq
MIRT2235596	hsa-miR-378d	CLIP-seq
MIRT2235597	hsa-miR-378e	CLIP-seq
MIRT2235598	hsa-miR-378f	CLIP-seq
MIRT2235599	hsa-miR-378h	CLIP-seq
MIRT2235600	hsa-miR-378i	CLIP-seq
MIRT2002616	hsa-miR-3910	CLIP-seq
MIRT1021353	hsa-miR-3935	CLIP-seq
MIRT2235601	hsa-miR-422a	CLIP-seq
MIRT2235602	hsa-miR-4257	CLIP-seq
MIRT1021354	hsa-miR-4280	CLIP-seq
MIRT2235603	hsa-miR-4320	CLIP-seq
MIRT1021355	hsa-miR-4462	CLIP-seq
MIRT2002618	hsa-miR-4491	CLIP-seq
MIRT2235606	hsa-miR-4638-3p	CLIP-seq
MIRT1021356	hsa-miR-4650-5p	CLIP-seq
MIRT2002620	hsa-miR-4657	CLIP-seq
MIRT2235607	hsa-miR-4684-5p	CLIP-seq
MIRT2002621	hsa-miR-4690-5p	CLIP-seq
MIRT1021357	hsa-miR-4709-5p	CLIP-seq
MIRT2002623	hsa-miR-4711-5p	CLIP-seq
MIRT1021358	hsa-miR-4731-5p	CLIP-seq
MIRT2002626	hsa-miR-4733-5p	CLIP-seq
MIRT2235609	hsa-miR-4752	CLIP-seq
MIRT1021359	hsa-miR-513a-5p	CLIP-seq
MIRT2539490	hsa-miR-548aa	CLIP-seq
MIRT2539491	hsa-miR-548o	CLIP-seq
MIRT1021360	hsa-miR-552	CLIP-seq
MIRT2539492	hsa-miR-570	CLIP-seq
MIRT2539493	hsa-miR-607	CLIP-seq
MIRT1021361	hsa-miR-612	CLIP-seq
MIRT2235610	hsa-miR-619	CLIP-seq
MIRT1021362	hsa-miR-668	CLIP-seq
MIRT2235611	hsa-miR-676	CLIP-seq
MIRT1021363	hsa-miR-761	CLIP-seq
MIRT1021364	hsa-miR-764	CLIP-seq
MIRT2539487	hsa-miR-1206	CLIP-seq
MIRT1021347	hsa-miR-1285	CLIP-seq
MIRT2539488	hsa-miR-1305	CLIP-seq
MIRT2539489	hsa-miR-1323	CLIP-seq
MIRT1021348	hsa-miR-1972	CLIP-seq
MIRT2235589	hsa-miR-2117	CLIP-seq
MIRT1021349	hsa-miR-214	CLIP-seq
MIRT1021350	hsa-miR-3120-3p	CLIP-seq
MIRT1021351	hsa-miR-3187-5p	CLIP-seq
MIRT2002613	hsa-miR-3188	CLIP-seq
MIRT2002614	hsa-miR-3194-3p	CLIP-seq
MIRT2235590	hsa-miR-3614-5p	CLIP-seq
MIRT1021352	hsa-miR-3619-5p	CLIP-seq
MIRT2235591	hsa-miR-3690	CLIP-seq
MIRT2235592	hsa-miR-3691-5p	CLIP-seq
MIRT2235593	hsa-miR-378	CLIP-seq
MIRT2235594	hsa-miR-378b	CLIP-seq
MIRT2235595	hsa-miR-378c	CLIP-seq
MIRT2235596	hsa-miR-378d	CLIP-seq
MIRT2235597	hsa-miR-378e	CLIP-seq
MIRT2235598	hsa-miR-378f	CLIP-seq
MIRT2235599	hsa-miR-378h	CLIP-seq
MIRT2235600	hsa-miR-378i	CLIP-seq
MIRT2002616	hsa-miR-3910	CLIP-seq
MIRT1021353	hsa-miR-3935	CLIP-seq
MIRT2235601	hsa-miR-422a	CLIP-seq
MIRT2235602	hsa-miR-4257	CLIP-seq
MIRT1021354	hsa-miR-4280	CLIP-seq
MIRT2235603	hsa-miR-4320	CLIP-seq
MIRT1021355	hsa-miR-4462	CLIP-seq
MIRT2002618	hsa-miR-4491	CLIP-seq
MIRT2235606	hsa-miR-4638-3p	CLIP-seq
MIRT1021356	hsa-miR-4650-5p	CLIP-seq
MIRT2002620	hsa-miR-4657	CLIP-seq
MIRT2235607	hsa-miR-4684-5p	CLIP-seq
MIRT2002621	hsa-miR-4690-5p	CLIP-seq
MIRT1021357	hsa-miR-4709-5p	CLIP-seq
MIRT2002623	hsa-miR-4711-5p	CLIP-seq
MIRT1021358	hsa-miR-4731-5p	CLIP-seq
MIRT2002626	hsa-miR-4733-5p	CLIP-seq
MIRT2235609	hsa-miR-4752	CLIP-seq
MIRT1021359	hsa-miR-513a-5p	CLIP-seq
MIRT2539490	hsa-miR-548aa	CLIP-seq
MIRT2539491	hsa-miR-548o	CLIP-seq
MIRT1021360	hsa-miR-552	CLIP-seq
MIRT2539492	hsa-miR-570	CLIP-seq
MIRT2539493	hsa-miR-607	CLIP-seq
MIRT1021361	hsa-miR-612	CLIP-seq
MIRT2235610	hsa-miR-619	CLIP-seq
MIRT1021362	hsa-miR-668	CLIP-seq
MIRT2235611	hsa-miR-676	CLIP-seq
MIRT1021363	hsa-miR-761	CLIP-seq
MIRT1021364	hsa-miR-764	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IEA
GO:0045296	Function	Cadherin binding	HDA	25468996
GO:0070062	Component	Extracellular exosome	HDA	23533145

Other IDs

• MIM: 620650
• HGNC: 14111
• e!Ensembl: ENSG00000167699

Protein

• UniProt ID: Q9HC38
• Protein name: Glyoxalase domain-containing protein 4
• PDB: 3ZI1
• Tissue specificity: TISSUE SPECIFICITY: Expressed in heart, brain, liver, kidney, pancreas and placenta. Not expressed in skeletal muscle and lung. {ECO:0000269|PubMed:11642406}.
• Sequence:

  MAARRALHFVFKVGNRFQTARFYRDVLGMKVESCSVARLECSGAISAHCSDYTRITEDSF
  SKPYDGKWSKTMVGFGPEDDHFVAELTYNYGVGDYKLGNDFMGITLASSQAVSNARKLEW
  PLTEVAEGVFETEAPGGYKFYLQNRSLPQSDPVLKVTLAVSDLQKSLNYWCNLLGMKIYE
  KDEEKQRALLGYADNQCKLELQGVKGGVDHAAAFGRIAFSCPQKELPDLEDLMKRENQKI
  LTPLVSLDTPGKATVQVVILADPDGHEICFVGDEAFRELSKMDPEGSKLLDDAMAADKSD
  EWFAKHNKPKASG

• Sequence length: 313

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
Uveal melanoma	Uncertain significance	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Liver carcinoma	Liver carcinoma	BEFREE	11642406, 12528892		★☆☆☆☆ Found in Text Mining only

Related Genes

No strongly related genes found yet for GLOD4.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to GLOD4.