Log in to bookmark this gene

Bookmark This Gene

Gene Gene information from NCBI Gene database.
Entrez ID 125111
Gene name Gap junction protein delta 3
Gene symbol GJD3
Synonyms (NCBI Gene)
CX31.9Cx30.2GJA11GJC1
Chromosome 17
Chromosome location 17q21.2
Summary This gene is a member of the large family of connexins that are required for the formation of gap junctions. Six connexin monomers form a hemichannel, or connexon, on the cell surface. This connexon can interact with a connexon from a neighboring cell, th
miRNA miRNA information provided by mirtarbase database.
438 Show/Hide all (438)
miRTarBase ID miRNA Experiments Reference
MIRT682526 hsa-miR-3609 HITS-CLIP 23706177
MIRT682525 hsa-miR-548ah-5p HITS-CLIP 23706177
MIRT682524 hsa-miR-4796-3p HITS-CLIP 23706177
MIRT682523 hsa-miR-552-3p HITS-CLIP 23706177
MIRT682522 hsa-miR-512-3p HITS-CLIP 23706177
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
27 Show/Hide all (27)
GO ID Ontology Definition Evidence Reference
GO:0005216 Function Monoatomic ion channel activity IEA
GO:0005243 Function Gap junction channel activity IEA
GO:0005515 Function Protein binding IPI 12154091
GO:0005886 Component Plasma membrane IEA
GO:0005886 Component Plasma membrane TAS 12154091
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
607425 19147 ENSG00000183153
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8N144
Protein name Gap junction delta-3 protein (Connexin-31.9) (Cx31.9) (Gap junction alpha-11 protein) (Gap junction chi-1 protein)
Protein function One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00029 Connexin 3 → 214 Connexin Family
Tissue specificity TISSUE SPECIFICITY: Expressed in vascular smooth muscle cells. Found in heart, colon, and artery (at protein level). Found in cerebral cortex, heart, liver, lung, kidney, spleen and testis. {ECO:0000269|PubMed:12154091, ECO:0000269|PubMed:12176752}.
Sequence
Sequence length 294
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Reactome Pathway
Gap junction assembly