GJD3 (gap junction protein delta 3)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 125111 |
| Gene name | Gap junction protein delta 3 |
| Gene symbol | GJD3 |
| Synonyms (NCBI Gene) |
CX31.9Cx30.2GJA11GJC1
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| Chromosome | 17 |
| Chromosome location | 17q21.2 |
| Summary | This gene is a member of the large family of connexins that are required for the formation of gap junctions. Six connexin monomers form a hemichannel, or connexon, on the cell surface. This connexon can interact with a connexon from a neighboring cell, th |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q8N144 | ||||||||||
| Protein name | Gap junction delta-3 protein (Connexin-31.9) (Cx31.9) (Gap junction alpha-11 protein) (Gap junction chi-1 protein) | ||||||||||
| Protein function | One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed in vascular smooth muscle cells. Found in heart, colon, and artery (at protein level). Found in cerebral cortex, heart, liver, lung, kidney, spleen and testis. {ECO:0000269|PubMed:12154091, ECO:0000269|PubMed:12176752}. | ||||||||||
| Sequence |
MGEWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPG |
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| Sequence length | 294 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Related Genes
Genes most often co-reported with GJD3 across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to GJD3 (see Related Genes above), that are NOT already directly curated for GJD3 itself -- a lead worth checking, not a confirmed association.
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