GABARAPL3 (GABA type A receptor associated protein like 3 (pseudogene))

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 23766
• Gene name: GABA type A receptor associated protein like 3 (pseudogene)
• Gene symbol: GABARAPL3
• Synonyms (NCBI Gene): ATG8D
• Chromosome: 15
• Chromosome location: 15q26.1

miRNA Show/Hide all (48)

miRTarBase ID	miRNA	Experiments	Reference
MIRT618138	hsa-miR-8485	HITS-CLIP	23824327
MIRT618137	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT618136	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT635156	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT618133	hsa-miR-6887-3p	HITS-CLIP	23824327
MIRT635155	hsa-miR-3162-3p	HITS-CLIP	23824327
MIRT618132	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT618139	hsa-miR-224-5p	HITS-CLIP	23824327
MIRT618138	hsa-miR-8485	HITS-CLIP	23824327
MIRT618137	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT618136	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT635156	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT618133	hsa-miR-6887-3p	HITS-CLIP	23824327
MIRT635155	hsa-miR-3162-3p	HITS-CLIP	23824327
MIRT618132	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT618139	hsa-miR-224-5p	HITS-CLIP	23824327
MIRT618138	hsa-miR-8485	HITS-CLIP	23824327
MIRT618137	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT618136	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT618135	hsa-miR-3691-3p	HITS-CLIP	23824327
MIRT618134	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT618133	hsa-miR-6887-3p	HITS-CLIP	23824327
MIRT618132	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT618131	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT618138	hsa-miR-8485	HITS-CLIP	23824327
MIRT618137	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT618136	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT635156	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT618133	hsa-miR-6887-3p	HITS-CLIP	23824327
MIRT635155	hsa-miR-3162-3p	HITS-CLIP	23824327
MIRT618132	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT618139	hsa-miR-224-5p	HITS-CLIP	23824327
MIRT618138	hsa-miR-8485	HITS-CLIP	23824327
MIRT618137	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT618136	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT635156	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT618133	hsa-miR-6887-3p	HITS-CLIP	23824327
MIRT635155	hsa-miR-3162-3p	HITS-CLIP	23824327
MIRT618132	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT618139	hsa-miR-224-5p	HITS-CLIP	23824327
MIRT618138	hsa-miR-8485	HITS-CLIP	23824327
MIRT618137	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT618136	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT618135	hsa-miR-3691-3p	HITS-CLIP	23824327
MIRT618134	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT618133	hsa-miR-6887-3p	HITS-CLIP	23824327
MIRT618132	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT618131	hsa-miR-2355-5p	HITS-CLIP	23824327

Gene ontology (GO) Show/Hide all (18)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000045	Process	Autophagosome assembly	IBA
GO:0000421	Component	Autophagosome membrane	IBA
GO:0000421	Component	Autophagosome membrane	IEA
GO:0000423	Process	Mitophagy	IBA
GO:0005543	Function	Phospholipid binding	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005776	Component	Autophagosome	IEA
GO:0005856	Component	Cytoskeleton	IEA
GO:0005874	Component	Microtubule	IEA
GO:0006914	Process	Autophagy	IEA
GO:0006995	Process	Cellular response to nitrogen starvation	IBA
GO:0008429	Function	Phosphatidylethanolamine binding	IBA
GO:0016020	Component	Membrane	IEA
GO:0031410	Component	Cytoplasmic vesicle	IEA
GO:0031625	Function	Ubiquitin protein ligase binding	IBA
GO:0031625	Function	Ubiquitin protein ligase binding	IEA
GO:0050811	Function	GABA receptor binding	IBA
GO:0097352	Process	Autophagosome maturation	IBA

Other IDs

• MIM: HGNC
• HGNC: 4069
• e!Ensembl: N/A

Protein

• UniProt ID: Q9BY60
• Protein name: Gamma-aminobutyric acid receptor-associated protein-like 3 (GABA(A) receptor-associated protein-like 3)
• Protein function: Ubiquitin-like modifier involved in autophagosome formation. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity). {ECO:00002
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF02991	Atg8	13 → 116	Autophagy protein Atg8 ubiquitin like	Domain

• Tissue specificity: TISSUE SPECIFICITY: Ubiquitous. Expressed at very high levels in the brain, heart, peripheral blood leukocytes, liver, kidney, placenta and skeletal muscle. Expressed at very low levels in thymus and small intestine. {ECO:0000269|PubMed:11414770}.
• Sequence:

  MKFQYKEVHPFEYRKKEGEKIRKKYPDRVPLIVEKAPKARVPDLDRRKYLVPSDLTDGQF
  YLLIRKRIHLRPEDALFFFVNNTIPPTSATMGQLYEDSHEEDDFLYVAYSNESVYGK

• Sequence length: 117

Related Genes

No strongly related genes found yet for GABARAPL3.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to GABARAPL3.