Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	139341
Gene name	FUN14 domain containing 1
Gene symbol	FUNDC1
Synonyms (NCBI Gene)	-
Chromosome	X
Chromosome location	Xp11.3
Summary	This gene encodes a protein with a FUN14 superfamily domain. The function of the encoded protein is not known. [provided by RefSeq, Sep 2011]

67 Show/Hide all (67)

miRTarBase ID	miRNA	Experiments	Reference
MIRT054547	hsa-miR-137	ImmunofluorescenceImmunohistochemistryLuciferase reporter assayqRT-PCRWestern blot	24573672
MIRT054547	hsa-miR-137	ImmunofluorescenceImmunohistochemistryLuciferase reporter assayqRT-PCRWestern blot	24573672
MIRT054547	hsa-miR-137	ImmunofluorescenceImmunohistochemistryLuciferase reporter assayqRT-PCRWestern blot	24573672
MIRT054547	hsa-miR-137	ImmunofluorescenceImmunohistochemistryLuciferase reporter assayqRT-PCRWestern blot	24573672
MIRT1006154	hsa-miR-1178	CLIP-seq
MIRT1006155	hsa-miR-23a	CLIP-seq
MIRT1006156	hsa-miR-23b	CLIP-seq
MIRT1006157	hsa-miR-23c	CLIP-seq
MIRT1006158	hsa-miR-3074-3p	CLIP-seq
MIRT1006159	hsa-miR-3120-3p	CLIP-seq
MIRT1006160	hsa-miR-320a	CLIP-seq
MIRT1006161	hsa-miR-320b	CLIP-seq
MIRT1006162	hsa-miR-320c	CLIP-seq
MIRT1006163	hsa-miR-320d	CLIP-seq
MIRT1006164	hsa-miR-3664-3p	CLIP-seq
MIRT1006165	hsa-miR-3692	CLIP-seq
MIRT1006166	hsa-miR-4263	CLIP-seq
MIRT1006167	hsa-miR-4328	CLIP-seq
MIRT1006168	hsa-miR-4429	CLIP-seq
MIRT1006169	hsa-miR-4509	CLIP-seq
MIRT1006170	hsa-miR-4744	CLIP-seq
MIRT1006171	hsa-miR-4799-5p	CLIP-seq
MIRT1006172	hsa-miR-520d-5p	CLIP-seq
MIRT1006173	hsa-miR-524-5p	CLIP-seq
MIRT1006174	hsa-miR-576-5p	CLIP-seq
MIRT1006175	hsa-miR-582-5p	CLIP-seq
MIRT1006176	hsa-miR-873	CLIP-seq
MIRT1006177	hsa-miR-944	CLIP-seq
MIRT1998137	hsa-miR-136	CLIP-seq
MIRT1998138	hsa-miR-198	CLIP-seq
MIRT1998139	hsa-miR-3145-3p	CLIP-seq
MIRT1998140	hsa-miR-3689a-5p	CLIP-seq
MIRT1998141	hsa-miR-3689b	CLIP-seq
MIRT1998142	hsa-miR-3689e	CLIP-seq
MIRT1998143	hsa-miR-3689f	CLIP-seq
MIRT1998144	hsa-miR-4267	CLIP-seq
MIRT1998145	hsa-miR-4768-5p	CLIP-seq
MIRT1006154	hsa-miR-1178	CLIP-seq
MIRT1998137	hsa-miR-136	CLIP-seq
MIRT1006155	hsa-miR-23a	CLIP-seq
MIRT1006156	hsa-miR-23b	CLIP-seq
MIRT1006157	hsa-miR-23c	CLIP-seq
MIRT1006164	hsa-miR-3664-3p	CLIP-seq
MIRT1998145	hsa-miR-4768-5p	CLIP-seq
MIRT1006176	hsa-miR-873	CLIP-seq
MIRT2535814	hsa-miR-1236	CLIP-seq
MIRT1998137	hsa-miR-136	CLIP-seq
MIRT2535815	hsa-miR-3115	CLIP-seq
MIRT2535816	hsa-miR-3123	CLIP-seq
MIRT2535817	hsa-miR-3185	CLIP-seq
MIRT2535818	hsa-miR-3942-5p	CLIP-seq
MIRT2535819	hsa-miR-4252	CLIP-seq
MIRT2535820	hsa-miR-4311	CLIP-seq
MIRT2535821	hsa-miR-4703-5p	CLIP-seq
MIRT2535822	hsa-miR-4738-3p	CLIP-seq
MIRT2535823	hsa-miR-4753-3p	CLIP-seq
MIRT1998145	hsa-miR-4768-5p	CLIP-seq
MIRT2535824	hsa-miR-4789-3p	CLIP-seq
MIRT2535825	hsa-miR-590-3p	CLIP-seq
MIRT2535826	hsa-miR-642b	CLIP-seq
MIRT2535827	hsa-miR-664	CLIP-seq
MIRT2535828	hsa-miR-942	CLIP-seq
MIRT2535814	hsa-miR-1236	CLIP-seq
MIRT2535815	hsa-miR-3115	CLIP-seq
MIRT2535819	hsa-miR-4252	CLIP-seq
MIRT2535823	hsa-miR-4753-3p	CLIP-seq
MIRT2535828	hsa-miR-942	CLIP-seq

17 Show/Hide all (17)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000422	Process	Autophagy of mitochondrion	IBA
GO:0000422	Process	Autophagy of mitochondrion	IDA	22267086
GO:0000422	Process	Autophagy of mitochondrion	IGI	22267086
GO:0000422	Process	Autophagy of mitochondrion	IMP	22267086
GO:0000423	Process	Mitophagy	IGI	34244144
GO:0001666	Process	Response to hypoxia	IDA	22267086
GO:0001666	Process	Response to hypoxia	IMP	22267086
GO:0005515	Function	Protein binding	IPI	20562859, 22267086, 24671035, 25416956, 25910212, 31515488
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IEA
GO:0005741	Component	Mitochondrial outer membrane	IBA
GO:0005741	Component	Mitochondrial outer membrane	IDA	22267086
GO:0005741	Component	Mitochondrial outer membrane	IEA
GO:0005741	Component	Mitochondrial outer membrane	TAS
GO:0006914	Process	Autophagy	IEA
GO:0008053	Process	Mitochondrial fusion	IGI	37931419
GO:0016020	Component	Membrane	IEA

MIM	HGNC	e!Ensembl
300871	28746	ENSG00000069509

Q8IVP5

Protein name

FUN14 domain-containing protein 1

Protein function

Integral mitochondrial outer-membrane protein that mediates the formation of mitochondria-associated endoplasmic reticulum membranes (MAMs) (PubMed:33972548). In turn, mediates angiogenesis and neoangiogenesis through interference with intracell

PDB

2N9X , 5GMV

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF04930	FUN14	54 → 153	FUN14 family	Family

Tissue specificity

TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:22267086}.

Sequence

MATRNPPPQDYESDDDSYEVLDLTEYARRHQWWNRVFGHSSGPMVEKYSVATQIVMGGVT
GWCAGFLFQKVGKLAATAVGGGFLLLQIASHSGYVQIDWKRVEKDVNKAKRQIKKRANKA
APEINNLIEEATEFIKQNIVISSGFVGGFLLGLAS

Sequence length

155

Interactions

View interactions

KEGG Pathway	Reactome Pathway
Mitophagy - animal	Receptor Mediated Mitophagy

FUNDC1 (FUN14 domain containing 1)

Bookmark This Gene