Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	219595
Gene name	Folate hydrolase 1B (pseudogene)
Gene symbol	FOLH1B
Synonyms (NCBI Gene)	FOLH2FOLHPPSMPSMA-LIKEPSMAL
Chromosome	11
Chromosome location	11q14.3

16 Show/Hide all (16)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003824	Function	Catalytic activity	IEA
GO:0004181	Function	Metallocarboxypeptidase activity	IDA	17241121
GO:0004181	Function	Metallocarboxypeptidase activity	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0006508	Process	Proteolysis	IEA
GO:0006537	Process	Glutamate biosynthetic process	IDA	17241121
GO:0008233	Function	Peptidase activity	IEA
GO:0008237	Function	Metallopeptidase activity	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0016805	Function	Dipeptidase activity	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0070062	Component	Extracellular exosome	HDA	23533145
GO:1900451	Process	Positive regulation of glutamate receptor signaling pathway	IDA	17241121
GO:1904492	Function	Ac-Asp-Glu binding	IDA	17241121

MIM	HGNC	e!Ensembl
609020	13636	HGNC

Q9HBA9

Protein name

Putative N-acetylated-alpha-linked acidic dipeptidase (NAALADase) (EC 3.4.-.-) (Cell growth-inhibiting gene 26 protein) (Prostate-specific membrane antigen-like protein) (Putative folate hydrolase 1B)

Protein function

Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. ; Exhibits a dipeptidyl-peptidase IV type activity.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF04253	TFR_dimer	319 → 439	Transferrin receptor-like dimerisation domain	Domain
PF04389	Peptidase_M28	49 → 256	Peptidase family M28	Family

Tissue specificity

TISSUE SPECIFICITY: Kidney and liver. Not expressed in the prostate. {ECO:0000269|PubMed:14716746}.

Sequence

MGGSAPPDSSWRGSLKVSYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEP
DRYVILGGHRDSWVFGGIDPQSGAAVVHETVRSFGTLKKEGWRPRRTILFASWDAEEFGL
LGSTEWAEDNSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVYNLTKELKSPDEGF
EGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSG
YPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYA
DKIYNISMKHPQEMKTYSLSFDSLFSAVKNFTEIASKFSERLQDFDKSNPILLRMMNDQL
MFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGDV
KRQISVAAFTVQAAAETLSEVA

Sequence length

442

Interactions

View interactions

Reactome Pathway
Aspartate and asparagine metabolism

Related Genes Genes most often co-reported with FOLH1B across shared curated disease and pathway associations. 0 Download as csv Download as pdf
No strongly related genes found yet for FOLH1B.

Diseases Linked via Similar Genes Diseases curated for genes most similar to FOLH1B (see Related Genes above), that are NOT already directly curated for FOLH1B itself -- a lead worth checking, not a confirmed association. 0 Download as csv Download as pdf
No additional diseases found yet through genes similar to FOLH1B.

FOLH1B (folate hydrolase 1B (pseudogene))

Bookmark This Gene