FNBP4 (formin binding protein 4)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 23360 |
| Gene name | Formin binding protein 4 |
| Gene symbol | FNBP4 |
| Synonyms (NCBI Gene) |
FBP30
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| Chromosome | 11 |
| Chromosome location | 11p11.2 |
| Summary | This gene encodes a protein containing two tryptophan-rich WW domains that binds the proline-rich formin homology 1 domains of formin family proteins, suggesting a role in the regulation of cytoskeletal dynamics during cell division and migration. It also |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q8N3X1 | |||||||||||||||
| Protein name | Formin-binding protein 4 (Formin-binding protein 30) | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Highly expressed in the eye. {ECO:0000269|PubMed:23703728}. | |||||||||||||||
| Sequence |
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| Sequence length | 1017 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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Related Genes
Genes most often co-reported with FNBP4 across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to FNBP4 (see Related Genes above), that are NOT already directly curated for FNBP4 itself -- a lead worth checking, not a confirmed association.
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