FCRL2 (Fc receptor like 2)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 79368
• Gene name: Fc receptor like 2
• Gene symbol: FCRL2
• Synonyms (NCBI Gene): CD307b, FCRH2, IFGP4, IRTA4, SPAP1, SPAP1A, SPAP1B, SPAP1C
• Chromosome: 1
• Chromosome location: 1q23.1
• Summary: This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembran

miRNA Show/Hide all (68)

miRTarBase ID	miRNA	Experiments	Reference
MIRT994112	hsa-miR-103b	CLIP-seq
MIRT994113	hsa-miR-1200	CLIP-seq
MIRT994114	hsa-miR-128	CLIP-seq
MIRT994115	hsa-miR-1283	CLIP-seq
MIRT994116	hsa-miR-1343	CLIP-seq
MIRT994117	hsa-miR-1827	CLIP-seq
MIRT994118	hsa-miR-224	CLIP-seq
MIRT994119	hsa-miR-3128	CLIP-seq
MIRT994120	hsa-miR-3148	CLIP-seq
MIRT994121	hsa-miR-337-5p	CLIP-seq
MIRT994122	hsa-miR-3622a-5p	CLIP-seq
MIRT994123	hsa-miR-3689d	CLIP-seq
MIRT994124	hsa-miR-3690	CLIP-seq
MIRT994125	hsa-miR-376a	CLIP-seq
MIRT994126	hsa-miR-376b	CLIP-seq
MIRT994127	hsa-miR-377	CLIP-seq
MIRT994128	hsa-miR-4254	CLIP-seq
MIRT994129	hsa-miR-4261	CLIP-seq
MIRT994130	hsa-miR-4324	CLIP-seq
MIRT994131	hsa-miR-4422	CLIP-seq
MIRT994132	hsa-miR-4452	CLIP-seq
MIRT994133	hsa-miR-4459	CLIP-seq
MIRT994134	hsa-miR-4649-3p	CLIP-seq
MIRT994135	hsa-miR-4680-3p	CLIP-seq
MIRT994136	hsa-miR-4720-5p	CLIP-seq
MIRT994137	hsa-miR-4799-3p	CLIP-seq
MIRT994138	hsa-miR-544b	CLIP-seq
MIRT994139	hsa-miR-875-3p	CLIP-seq
MIRT1994788	hsa-miR-148a	CLIP-seq
MIRT1994789	hsa-miR-148b	CLIP-seq
MIRT1994790	hsa-miR-152	CLIP-seq
MIRT1994791	hsa-miR-1825	CLIP-seq
MIRT1994792	hsa-miR-338-3p	CLIP-seq
MIRT1994793	hsa-miR-3665	CLIP-seq
MIRT1994794	hsa-miR-3713	CLIP-seq
MIRT1994795	hsa-miR-4277	CLIP-seq
MIRT1994796	hsa-miR-448	CLIP-seq
MIRT1994797	hsa-miR-548g	CLIP-seq
MIRT1994798	hsa-miR-657	CLIP-seq
MIRT1994799	hsa-miR-659	CLIP-seq
MIRT994112	hsa-miR-103b	CLIP-seq
MIRT2228936	hsa-miR-1246	CLIP-seq
MIRT2228937	hsa-miR-3134	CLIP-seq
MIRT1994792	hsa-miR-338-3p	CLIP-seq
MIRT994125	hsa-miR-376a	CLIP-seq
MIRT994126	hsa-miR-376b	CLIP-seq
MIRT2228938	hsa-miR-4320	CLIP-seq
MIRT994132	hsa-miR-4452	CLIP-seq
MIRT994135	hsa-miR-4680-3p	CLIP-seq
MIRT2449594	hsa-miR-1253	CLIP-seq
MIRT2449595	hsa-miR-1270	CLIP-seq
MIRT2449596	hsa-miR-129-5p	CLIP-seq
MIRT1994788	hsa-miR-148a	CLIP-seq
MIRT1994789	hsa-miR-148b	CLIP-seq
MIRT1994790	hsa-miR-152	CLIP-seq
MIRT1994791	hsa-miR-1825	CLIP-seq
MIRT2449597	hsa-miR-4434	CLIP-seq
MIRT2449598	hsa-miR-4516	CLIP-seq
MIRT2449599	hsa-miR-4531	CLIP-seq
MIRT2449600	hsa-miR-494	CLIP-seq
MIRT2449601	hsa-miR-620	CLIP-seq
MIRT1994799	hsa-miR-659	CLIP-seq
MIRT2680938	hsa-miR-3065-5p	CLIP-seq
MIRT2680939	hsa-miR-450b-5p	CLIP-seq
MIRT2680940	hsa-miR-513c	CLIP-seq
MIRT2680941	hsa-miR-514b-5p	CLIP-seq
MIRT2680942	hsa-miR-518a-5p	CLIP-seq
MIRT2680943	hsa-miR-527	CLIP-seq

Gene ontology (GO) Show/Hide all (14)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004888	Function	Transmembrane signaling receptor activity	IBA
GO:0005515	Function	Protein binding	IPI	25416956, 28514442, 32296183, 33961781
GO:0005886	Component	Plasma membrane	IEA
GO:0006955	Process	Immune response	IBA
GO:0007166	Process	Cell surface receptor signaling pathway	IBA
GO:0007267	Process	Cell-cell signaling	NAS	11162587
GO:0009897	Component	External side of plasma membrane	IBA
GO:0009986	Component	Cell surface	IDA	16849395
GO:0009986	Component	Cell surface	IEA
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	NAS	11162587
GO:0019903	Function	Protein phosphatase binding	IEA
GO:0019903	Function	Protein phosphatase binding	IPI	11162587
GO:0035591	Function	Signaling adaptor activity	IDA	11162587

Other IDs

• MIM: 606509
• HGNC: 14875
• e!Ensembl: ENSG00000132704

Protein

• UniProt ID: Q96LA5
• Protein name: Fc receptor-like protein 2 (FcR-like protein 2) (FcRL2) (Fc receptor homolog 2) (FcRH2) (IFGP family protein 4) (Immunoglobulin receptor translocation-associated protein 4) (SH2 domain-containing phosphatase anchor protein 1) (CD antigen CD307b)
• Protein function: May have an regulatory role in normal and neoplastic B cell development.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF13895	Ig_2	206 → 293	Immunoglobulin domain	Domain
  PF13895	Ig_2	299 → 386	Immunoglobulin domain	Domain
  PF13895	Ig_2	19 → 102	Immunoglobulin domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Expressed in the secondary lymphoid organs, spleen and lymph node. Expression is limited to the mature B-cell lines. Highly expressed in CD19 and within the mantle zones of the tonsil tissue. Isoform 2 is expressed in the spleen, perip
• Sequence:

  MLLWSLLVIFDAVTEQADSLTLVAPSSVFEGDSIVLKCQGEQNWKIQKMAYHKDNKELSV
  FKKFSDFLIQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIE
  GGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAE
  TVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWY
  REATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRP
  VLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLSLTA
  EHSGNYSCEANNGLGAQCSEAVPVSISGPDGYRRDLMTAGVLWGLFGVLGFTGVALLLYA
  LFHKISGESSATNEPRGASRPNPQEFTYSSPTPDMEELQPVYVNVGSVDVDVVYSQVWSM
  QQPESSANIRTLLENKDSQVIYSSVKKS

• Sequence length: 508

Related Genes

No strongly related genes found yet for FCRL2.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to FCRL2.