Log in to bookmark this gene

Bookmark This Gene

Gene Gene information from NCBI Gene database.
Entrez ID 150726
Gene name F-box protein 41
Gene symbol FBXO41
Synonyms (NCBI Gene)
FBX41
Chromosome 2
Chromosome location 2p13.2
Summary This gene encodes a member of the F-box protein family, which is characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one of the four subunits of the SCF ubiquitin protein ligase complex that plays a role in phosphor
miRNA miRNA information provided by mirtarbase database.
594 Show/Hide all (594)
miRTarBase ID miRNA Experiments Reference
MIRT051175 hsa-miR-16-5p CLASH 23622248
MIRT513243 hsa-miR-7845-5p PAR-CLIP 20371350
MIRT513242 hsa-miR-4436b-3p PAR-CLIP 20371350
MIRT513241 hsa-miR-4632-5p PAR-CLIP 20371350
MIRT513240 hsa-miR-6735-5p PAR-CLIP 20371350
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
8 Show/Hide all (8)
GO ID Ontology Definition Evidence Reference
GO:0001764 Process Neuron migration IEA
GO:0005829 Component Cytosol TAS
GO:0007268 Process Chemical synaptic transmission IEA
GO:0010467 Process Gene expression IEA
GO:0021542 Process Dentate gyrus development IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
609108 29409 ENSG00000163013
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8TF61
Protein name F-box only protein 41
Protein function Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
PDB 8S1R
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF12937 F-box-like 555 → 595 F-box-like Domain
Sequence
MASLDLPYRCPRCGEHKRFRSLSSLRAHLEYSHTYETLYILSKTNSICDGAAAAAAAAAA
ASGFPLAPEPAALLAVPGARREVFESTSFQGKEQAAGPSPAAPHLLHHHHHHAPLAHFPG
DLVPASLPCEELAEPGLVPAAAARYALREIEIPLGELFARKSVASSACSTPPPGPGPGPC
PGPASASPASPSPADVAYEEGLARLKIRALEKLEVDRRLERLSEEVEQKIAGQVGRLQAE
LERKAAELETARQESARLGREKEELEERASELSRQVDVSVELLASLKQDLVHKEQELSRK
QQEVVQIDQFLKETAAREASAKLRLQQFIEELLERADRAERQLQVISSSCGSTPSASLGR
GGGGGGAGPNARGPGRMREHHVGPAVPNTYAVSRHGSSPSTGASSRVPAASQSSGCYDSD
SLELPRPEEGAPEDSGPGGLGTRAQAANGGSERSQPPRSSGLRRQAIQNWQRRPRRHSTE
GEEGDVSDVGSRTTESEAEGPLDAPRPGPAMAGPLSSCRLSARPEGGSGRGRRAERVSPS
RSNEVISPEILKMRAALFCIFTYLDTRTLLHAAEVCRDWRFVARHPAVWTRVLLENARVC
SKFLAMLAQWCTQAHSLTLQNLKPRQRGKKESKEEYARSTRGCLEAGLESLLKAAGGNLL
ILRISHCPNILTDRSLWLASCYCRALQAVTYRSATDPVGHEVIWALGAGCREIVSLQVAP
LHPCQQPTRFSNRCLQMIGRCWPHLRALGVGGAGCGVQGLASLARNCMRLQVLELDHVSE
ITQEVAAEVCREGLKGLEMLVLTATPVTPKALLHFNSICRNLKSIVVQIGIADYFKEPSS
PEAQKLFEDMVTKLQALRRRPGFSKILHIKVEGGC
Sequence length 875
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Reactome Pathway
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation