FAM162A (family with sequence similarity 162 member A)

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Gene miRNA Transcription factors Gene ontology Other IDs Protein Diseases linked via similar genes

Gene

• Entrez ID: 26355
• Gene name: Family with sequence similarity 162 member A
• Gene symbol: FAM162A
• Synonyms (NCBI Gene): C3orf28, E2IG5, HGTD-P
• Chromosome: 3
• Chromosome location: 3q21.1

miRNA Show/Hide all (82)

miRTarBase ID	miRNA	Experiments	Reference
MIRT438212	hsa-miR-139-5p	Luciferase reporter assay	24333693
MIRT438212	hsa-miR-139-5p	Luciferase reporter assay	24333693
MIRT452632	hsa-miR-302f	PAR-CLIP	23592263
MIRT452631	hsa-miR-1247-3p	PAR-CLIP	23592263
MIRT452630	hsa-miR-6746-5p	PAR-CLIP	23592263
MIRT452629	hsa-miR-219b-3p	PAR-CLIP	23592263
MIRT452628	hsa-miR-3160-3p	PAR-CLIP	23592263
MIRT452627	hsa-miR-558	PAR-CLIP	23592263
MIRT452626	hsa-miR-4487	PAR-CLIP	23592263
MIRT452625	hsa-miR-377-5p	PAR-CLIP	23592263
MIRT452624	hsa-miR-6086	PAR-CLIP	23592263
MIRT452623	hsa-miR-6499-3p	PAR-CLIP	23592263
MIRT452622	hsa-miR-139-3p	PAR-CLIP	23592263
MIRT452621	hsa-miR-455-3p	PAR-CLIP	23592263
MIRT452620	hsa-miR-1273e	PAR-CLIP	23592263
MIRT452619	hsa-miR-6516-5p	PAR-CLIP	23592263
MIRT452632	hsa-miR-302f	PAR-CLIP	23592263
MIRT452631	hsa-miR-1247-3p	PAR-CLIP	23592263
MIRT452630	hsa-miR-6746-5p	PAR-CLIP	23592263
MIRT452629	hsa-miR-219b-3p	PAR-CLIP	23592263
MIRT452628	hsa-miR-3160-3p	PAR-CLIP	23592263
MIRT452627	hsa-miR-558	PAR-CLIP	23592263
MIRT452626	hsa-miR-4487	PAR-CLIP	23592263
MIRT452625	hsa-miR-377-5p	PAR-CLIP	23592263
MIRT452624	hsa-miR-6086	PAR-CLIP	23592263
MIRT452623	hsa-miR-6499-3p	PAR-CLIP	23592263
MIRT452622	hsa-miR-139-3p	PAR-CLIP	23592263
MIRT452621	hsa-miR-455-3p	PAR-CLIP	23592263
MIRT452620	hsa-miR-1273e	PAR-CLIP	23592263
MIRT452619	hsa-miR-6516-5p	PAR-CLIP	23592263
MIRT981497	hsa-miR-3120-3p	CLIP-seq
MIRT981498	hsa-miR-3682-5p	CLIP-seq
MIRT981499	hsa-miR-922	CLIP-seq
MIRT1990778	hsa-miR-4668-3p	CLIP-seq
MIRT1990779	hsa-miR-4698	CLIP-seq
MIRT1990780	hsa-miR-875-5p	CLIP-seq
MIRT2224999	hsa-miR-1290	CLIP-seq
MIRT2225000	hsa-miR-1305	CLIP-seq
MIRT2225001	hsa-miR-1343	CLIP-seq
MIRT2225002	hsa-miR-140-3p	CLIP-seq
MIRT981497	hsa-miR-3120-3p	CLIP-seq
MIRT2225003	hsa-miR-3167	CLIP-seq
MIRT2225004	hsa-miR-3622a-5p	CLIP-seq
MIRT981498	hsa-miR-3682-5p	CLIP-seq
MIRT2225005	hsa-miR-3690	CLIP-seq
MIRT2225006	hsa-miR-374c	CLIP-seq
MIRT2225007	hsa-miR-4254	CLIP-seq
MIRT2225008	hsa-miR-4269	CLIP-seq
MIRT2225009	hsa-miR-4438	CLIP-seq
MIRT1990778	hsa-miR-4668-3p	CLIP-seq
MIRT1990779	hsa-miR-4698	CLIP-seq
MIRT2225010	hsa-miR-501-5p	CLIP-seq
MIRT2225011	hsa-miR-5095	CLIP-seq
MIRT2225012	hsa-miR-607	CLIP-seq
MIRT2225013	hsa-miR-655	CLIP-seq
MIRT1990780	hsa-miR-875-5p	CLIP-seq
MIRT2225014	hsa-miR-876-5p	CLIP-seq
MIRT981499	hsa-miR-922	CLIP-seq
MIRT2224999	hsa-miR-1290	CLIP-seq
MIRT2225000	hsa-miR-1305	CLIP-seq
MIRT2225001	hsa-miR-1343	CLIP-seq
MIRT2225003	hsa-miR-3167	CLIP-seq
MIRT2225004	hsa-miR-3622a-5p	CLIP-seq
MIRT2225005	hsa-miR-3690	CLIP-seq
MIRT2225007	hsa-miR-4254	CLIP-seq
MIRT1990778	hsa-miR-4668-3p	CLIP-seq
MIRT1990779	hsa-miR-4698	CLIP-seq
MIRT2528582	hsa-miR-4803	CLIP-seq
MIRT2225012	hsa-miR-607	CLIP-seq
MIRT2225014	hsa-miR-876-5p	CLIP-seq
MIRT2224999	hsa-miR-1290	CLIP-seq
MIRT2225000	hsa-miR-1305	CLIP-seq
MIRT2225001	hsa-miR-1343	CLIP-seq
MIRT2225003	hsa-miR-3167	CLIP-seq
MIRT2225004	hsa-miR-3622a-5p	CLIP-seq
MIRT2225005	hsa-miR-3690	CLIP-seq
MIRT2225007	hsa-miR-4254	CLIP-seq
MIRT1990778	hsa-miR-4668-3p	CLIP-seq
MIRT1990779	hsa-miR-4698	CLIP-seq
MIRT2528582	hsa-miR-4803	CLIP-seq
MIRT2225012	hsa-miR-607	CLIP-seq
MIRT2225014	hsa-miR-876-5p	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
HIF1A	Unknown	15082785

Gene ontology (GO) Show/Hide all (19)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	15082785, 16698020
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IBA
GO:0005739	Component	Mitochondrion	IDA
GO:0005739	Component	Mitochondrion	IEA
GO:0005829	Component	Cytosol	IDA
GO:0006915	Process	Apoptotic process	IEA
GO:0016020	Component	Membrane	IEA
GO:0031966	Component	Mitochondrial membrane	IEA
GO:0043065	Process	Positive regulation of apoptotic process	IDA	15082785
GO:0043065	Process	Positive regulation of apoptotic process	IEA
GO:0051402	Process	Neuron apoptotic process	IBA
GO:0051402	Process	Neuron apoptotic process	IEA
GO:0071456	Process	Cellular response to hypoxia	IBA
GO:0071456	Process	Cellular response to hypoxia	IDA	15082785
GO:0071456	Process	Cellular response to hypoxia	IEA
GO:0090200	Process	Positive regulation of release of cytochrome c from mitochondria	IBA
GO:0090200	Process	Positive regulation of release of cytochrome c from mitochondria	IDA	15082785
GO:0090200	Process	Positive regulation of release of cytochrome c from mitochondria	IEA

Other IDs

• MIM: 608017
• HGNC: 17865
• e!Ensembl: ENSG00000114023

Protein

• UniProt ID: Q96A26
• Protein name: Protein FAM162A (E2-induced gene 5 protein) (Growth and transformation-dependent protein) (HGTD-P)
• Protein function: Proposed to be involved in regulation of apoptosis; the exact mechanism may differ between cell types/tissues (PubMed:15082785). May be involved in hypoxia-induced cell death of transformed cells implicating cytochrome C release and caspase acti
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF06388	DUF1075	16 → 133	Protein of unknown function (DUF1075)	Family

• Sequence:

  MGSLSGLRLAAGSCFRLCERDVSSSLRLTRSSDLKRINGFCTKPQESPGAPSRTYNRVPL
  HKPTDWQKKILIWSGRFKKEDEIPETVSLEMLDAAKNKMRVKISYLMIALTVVGCIFMVI
  EGKKAAQRHETLTSLNLEKKARLKEEAAMKAKTE

• Sequence length: 154

Related Genes

No strongly related genes found yet for FAM162A.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to FAM162A.