F2RL2 (coagulation factor II thrombin receptor like 2)

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Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 2151
• Gene name: Coagulation factor II thrombin receptor like 2
• Gene symbol: F2RL2
• Synonyms (NCBI Gene): PAR-3, PAR3
• Chromosome: 5
• Chromosome location: 5q13.3
• Summary: This gene encodes a member of the protease-activated receptor (PAR) family which is a subfamily of the seven transmembrane G protein-coupled cell surface receptor family. The encoded protein acts as a cofactor in the thrombin-mediated cleavage and activat

miRNA Show/Hide all (303)

miRTarBase ID	miRNA	Experiments	Reference
MIRT681631	hsa-miR-4662a-3p	HITS-CLIP	23706177
MIRT681630	hsa-miR-7851-3p	HITS-CLIP	23706177
MIRT681629	hsa-miR-1910-3p	HITS-CLIP	23706177
MIRT681628	hsa-miR-6511a-5p	HITS-CLIP	23706177
MIRT681627	hsa-miR-4257	HITS-CLIP	23706177
MIRT681626	hsa-miR-3192-5p	HITS-CLIP	23706177
MIRT681625	hsa-miR-3661	HITS-CLIP	23706177
MIRT681624	hsa-miR-631	HITS-CLIP	23706177
MIRT681623	hsa-miR-1827	HITS-CLIP	23706177
MIRT681622	hsa-miR-377-5p	HITS-CLIP	23706177
MIRT681621	hsa-miR-6086	HITS-CLIP	23706177
MIRT681620	hsa-miR-2467-3p	HITS-CLIP	23706177
MIRT681619	hsa-miR-3612	HITS-CLIP	23706177
MIRT681618	hsa-miR-650	HITS-CLIP	23706177
MIRT681617	hsa-miR-7106-5p	HITS-CLIP	23706177
MIRT681616	hsa-miR-149-3p	HITS-CLIP	23706177
MIRT681615	hsa-miR-4728-5p	HITS-CLIP	23706177
MIRT681614	hsa-miR-6785-5p	HITS-CLIP	23706177
MIRT681613	hsa-miR-6883-5p	HITS-CLIP	23706177
MIRT681612	hsa-miR-6799-5p	HITS-CLIP	23706177
MIRT681611	hsa-miR-4684-3p	HITS-CLIP	23706177
MIRT681610	hsa-miR-6807-5p	HITS-CLIP	23706177
MIRT681609	hsa-miR-106a-3p	HITS-CLIP	23706177
MIRT681608	hsa-miR-1273h-5p	HITS-CLIP	23706177
MIRT681607	hsa-miR-30b-3p	HITS-CLIP	23706177
MIRT681606	hsa-miR-3689a-3p	HITS-CLIP	23706177
MIRT681605	hsa-miR-3689b-3p	HITS-CLIP	23706177
MIRT681604	hsa-miR-3689c	HITS-CLIP	23706177
MIRT681603	hsa-miR-6779-5p	HITS-CLIP	23706177
MIRT681602	hsa-miR-6780a-5p	HITS-CLIP	23706177
MIRT540627	hsa-miR-4709-5p	PAR-CLIP	21572407
MIRT540625	hsa-miR-6849-3p	PAR-CLIP	21572407
MIRT540626	hsa-miR-939-3p	PAR-CLIP	21572407
MIRT540624	hsa-miR-1285-3p	PAR-CLIP	21572407
MIRT540623	hsa-miR-3187-5p	PAR-CLIP	21572407
MIRT540622	hsa-miR-5189-5p	PAR-CLIP	21572407
MIRT540621	hsa-miR-612	PAR-CLIP	21572407
MIRT540620	hsa-miR-6860	PAR-CLIP	21572407
MIRT540619	hsa-miR-873-3p	PAR-CLIP	21572407
MIRT540618	hsa-miR-661	PAR-CLIP	21572407
MIRT540617	hsa-miR-196a-3p	PAR-CLIP	21572407
MIRT540616	hsa-miR-3672	PAR-CLIP	21572407
MIRT540615	hsa-miR-6864-3p	PAR-CLIP	21572407
MIRT497780	hsa-miR-8083	PAR-CLIP	22291592
MIRT497779	hsa-miR-6830-5p	PAR-CLIP	22291592
MIRT497778	hsa-miR-205-5p	PAR-CLIP	22291592
MIRT497777	hsa-miR-561-5p	PAR-CLIP	22291592
MIRT450273	hsa-miR-4781-3p	PAR-CLIP	22100165
MIRT450272	hsa-miR-4635	PAR-CLIP	22100165
MIRT450271	hsa-miR-570-3p	PAR-CLIP	22100165
MIRT450270	hsa-miR-2116-5p	PAR-CLIP	22100165
MIRT450269	hsa-miR-22-5p	PAR-CLIP	22100165
MIRT450268	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT450267	hsa-miR-4273	PAR-CLIP	22100165
MIRT450266	hsa-miR-7156-5p	PAR-CLIP	22100165
MIRT450265	hsa-miR-4677-5p	PAR-CLIP	22100165
MIRT450264	hsa-miR-6739-3p	PAR-CLIP	22100165
MIRT681609	hsa-miR-106a-3p	PAR-CLIP	27292025
MIRT681608	hsa-miR-1273h-5p	PAR-CLIP	27292025
MIRT681616	hsa-miR-149-3p	PAR-CLIP	27292025
MIRT681623	hsa-miR-1827	PAR-CLIP	27292025
MIRT681629	hsa-miR-1910-3p	PAR-CLIP	27292025
MIRT681620	hsa-miR-2467-3p	PAR-CLIP	27292025
MIRT681607	hsa-miR-30b-3p	PAR-CLIP	27292025
MIRT681626	hsa-miR-3192-5p	PAR-CLIP	27292025
MIRT681619	hsa-miR-3612	PAR-CLIP	27292025
MIRT681625	hsa-miR-3661	PAR-CLIP	27292025
MIRT681606	hsa-miR-3689a-3p	PAR-CLIP	27292025
MIRT681605	hsa-miR-3689b-3p	PAR-CLIP	27292025
MIRT681604	hsa-miR-3689c	PAR-CLIP	27292025
MIRT681622	hsa-miR-377-5p	PAR-CLIP	27292025
MIRT681627	hsa-miR-4257	PAR-CLIP	27292025
MIRT681631	hsa-miR-4662a-3p	PAR-CLIP	27292025
MIRT681611	hsa-miR-4684-3p	PAR-CLIP	27292025
MIRT681615	hsa-miR-4728-5p	PAR-CLIP	27292025
MIRT681621	hsa-miR-6086	PAR-CLIP	27292025
MIRT681624	hsa-miR-631	PAR-CLIP	27292025
MIRT681618	hsa-miR-650	PAR-CLIP	27292025
MIRT681628	hsa-miR-6511a-5p	PAR-CLIP	27292025
MIRT681603	hsa-miR-6779-5p	PAR-CLIP	27292025
MIRT681602	hsa-miR-6780a-5p	PAR-CLIP	27292025
MIRT681614	hsa-miR-6785-5p	PAR-CLIP	27292025
MIRT681612	hsa-miR-6799-5p	PAR-CLIP	27292025
MIRT681610	hsa-miR-6807-5p	PAR-CLIP	27292025
MIRT681613	hsa-miR-6883-5p	PAR-CLIP	27292025
MIRT681617	hsa-miR-7106-5p	PAR-CLIP	27292025
MIRT681630	hsa-miR-7851-3p	PAR-CLIP	27292025
MIRT681631	hsa-miR-4662a-3p	HITS-CLIP	23706177
MIRT681630	hsa-miR-7851-3p	HITS-CLIP	23706177
MIRT681629	hsa-miR-1910-3p	HITS-CLIP	23706177
MIRT681628	hsa-miR-6511a-5p	HITS-CLIP	23706177
MIRT681627	hsa-miR-4257	HITS-CLIP	23706177
MIRT681626	hsa-miR-3192-5p	HITS-CLIP	23706177
MIRT681625	hsa-miR-3661	HITS-CLIP	23706177
MIRT681624	hsa-miR-631	HITS-CLIP	23706177
MIRT681623	hsa-miR-1827	HITS-CLIP	23706177
MIRT681622	hsa-miR-377-5p	HITS-CLIP	23706177
MIRT681621	hsa-miR-6086	HITS-CLIP	23706177
MIRT681620	hsa-miR-2467-3p	HITS-CLIP	23706177
MIRT681619	hsa-miR-3612	HITS-CLIP	23706177
MIRT681618	hsa-miR-650	HITS-CLIP	23706177
MIRT681617	hsa-miR-7106-5p	HITS-CLIP	23706177
MIRT681616	hsa-miR-149-3p	HITS-CLIP	23706177
MIRT681615	hsa-miR-4728-5p	HITS-CLIP	23706177
MIRT681614	hsa-miR-6785-5p	HITS-CLIP	23706177
MIRT681613	hsa-miR-6883-5p	HITS-CLIP	23706177
MIRT681612	hsa-miR-6799-5p	HITS-CLIP	23706177
MIRT681611	hsa-miR-4684-3p	HITS-CLIP	23706177
MIRT681610	hsa-miR-6807-5p	HITS-CLIP	23706177
MIRT681609	hsa-miR-106a-3p	HITS-CLIP	23706177
MIRT681608	hsa-miR-1273h-5p	HITS-CLIP	23706177
MIRT681607	hsa-miR-30b-3p	HITS-CLIP	23706177
MIRT681606	hsa-miR-3689a-3p	HITS-CLIP	23706177
MIRT681605	hsa-miR-3689b-3p	HITS-CLIP	23706177
MIRT681604	hsa-miR-3689c	HITS-CLIP	23706177
MIRT681603	hsa-miR-6779-5p	HITS-CLIP	23706177
MIRT681602	hsa-miR-6780a-5p	HITS-CLIP	23706177
MIRT540627	hsa-miR-4709-5p	PAR-CLIP	21572407
MIRT540625	hsa-miR-6849-3p	PAR-CLIP	21572407
MIRT540626	hsa-miR-939-3p	PAR-CLIP	21572407
MIRT540624	hsa-miR-1285-3p	PAR-CLIP	21572407
MIRT540623	hsa-miR-3187-5p	PAR-CLIP	21572407
MIRT540622	hsa-miR-5189-5p	PAR-CLIP	21572407
MIRT540621	hsa-miR-612	PAR-CLIP	21572407
MIRT540620	hsa-miR-6860	PAR-CLIP	21572407
MIRT540619	hsa-miR-873-3p	PAR-CLIP	21572407
MIRT540618	hsa-miR-661	PAR-CLIP	21572407
MIRT540617	hsa-miR-196a-3p	PAR-CLIP	21572407
MIRT540616	hsa-miR-3672	PAR-CLIP	21572407
MIRT540615	hsa-miR-6864-3p	PAR-CLIP	21572407
MIRT497780	hsa-miR-8083	PAR-CLIP	22291592
MIRT497779	hsa-miR-6830-5p	PAR-CLIP	22291592
MIRT497778	hsa-miR-205-5p	PAR-CLIP	22291592
MIRT497777	hsa-miR-561-5p	PAR-CLIP	22291592
MIRT450273	hsa-miR-4781-3p	PAR-CLIP	22100165
MIRT450272	hsa-miR-4635	PAR-CLIP	22100165
MIRT450271	hsa-miR-570-3p	PAR-CLIP	22100165
MIRT450270	hsa-miR-2116-5p	PAR-CLIP	22100165
MIRT450269	hsa-miR-22-5p	PAR-CLIP	22100165
MIRT450268	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT450267	hsa-miR-4273	PAR-CLIP	22100165
MIRT450266	hsa-miR-7156-5p	PAR-CLIP	22100165
MIRT450265	hsa-miR-4677-5p	PAR-CLIP	22100165
MIRT450264	hsa-miR-6739-3p	PAR-CLIP	22100165
MIRT755665	hsa-miR-582-5p	Luciferase reporter assay, qRT-PCR	36540097
MIRT974467	hsa-miR-1285	CLIP-seq
MIRT974468	hsa-miR-2114	CLIP-seq
MIRT974469	hsa-miR-24	CLIP-seq
MIRT974470	hsa-miR-3122	CLIP-seq
MIRT974471	hsa-miR-3148	CLIP-seq
MIRT974472	hsa-miR-338-3p	CLIP-seq
MIRT974473	hsa-miR-34b	CLIP-seq
MIRT974474	hsa-miR-3677-5p	CLIP-seq
MIRT974475	hsa-miR-3913-5p	CLIP-seq
MIRT974476	hsa-miR-3929	CLIP-seq
MIRT974477	hsa-miR-4284	CLIP-seq
MIRT974478	hsa-miR-4419b	CLIP-seq
MIRT974479	hsa-miR-4420	CLIP-seq
MIRT974480	hsa-miR-4424	CLIP-seq
MIRT974481	hsa-miR-4433	CLIP-seq
MIRT974482	hsa-miR-4475	CLIP-seq
MIRT974483	hsa-miR-4476	CLIP-seq
MIRT974484	hsa-miR-4478	CLIP-seq
MIRT974485	hsa-miR-4530	CLIP-seq
MIRT974486	hsa-miR-4649-3p	CLIP-seq
MIRT974487	hsa-miR-4668-5p	CLIP-seq
MIRT974488	hsa-miR-4682	CLIP-seq
MIRT974489	hsa-miR-4743	CLIP-seq
MIRT974490	hsa-miR-4786-5p	CLIP-seq
MIRT974491	hsa-miR-485-5p	CLIP-seq
MIRT974492	hsa-miR-665	CLIP-seq
MIRT1988715	hsa-miR-186	CLIP-seq
MIRT974468	hsa-miR-2114	CLIP-seq
MIRT974469	hsa-miR-24	CLIP-seq
MIRT974470	hsa-miR-3122	CLIP-seq
MIRT1988716	hsa-miR-3192	CLIP-seq
MIRT974474	hsa-miR-3677-5p	CLIP-seq
MIRT1988717	hsa-miR-3714	CLIP-seq
MIRT1988718	hsa-miR-383	CLIP-seq
MIRT974475	hsa-miR-3913-5p	CLIP-seq
MIRT1988719	hsa-miR-3922-5p	CLIP-seq
MIRT974476	hsa-miR-3929	CLIP-seq
MIRT974477	hsa-miR-4284	CLIP-seq
MIRT1988720	hsa-miR-4311	CLIP-seq
MIRT974478	hsa-miR-4419b	CLIP-seq
MIRT974481	hsa-miR-4433	CLIP-seq
MIRT1988721	hsa-miR-4459	CLIP-seq
MIRT974484	hsa-miR-4478	CLIP-seq
MIRT1988722	hsa-miR-4768-3p	CLIP-seq
MIRT1988723	hsa-miR-4772-5p	CLIP-seq
MIRT974490	hsa-miR-4786-5p	CLIP-seq
MIRT974491	hsa-miR-485-5p	CLIP-seq
MIRT1988724	hsa-miR-499a-5p	CLIP-seq
MIRT1988725	hsa-miR-505	CLIP-seq
MIRT1988726	hsa-miR-890	CLIP-seq
MIRT2223124	hsa-miR-1225-3p	CLIP-seq
MIRT2223125	hsa-miR-1233	CLIP-seq
MIRT2223126	hsa-miR-1255a	CLIP-seq
MIRT2223127	hsa-miR-1255b	CLIP-seq
MIRT2223128	hsa-miR-1273e	CLIP-seq
MIRT974468	hsa-miR-2114	CLIP-seq
MIRT974469	hsa-miR-24	CLIP-seq
MIRT974470	hsa-miR-3122	CLIP-seq
MIRT1988716	hsa-miR-3192	CLIP-seq
MIRT974472	hsa-miR-338-3p	CLIP-seq
MIRT2223129	hsa-miR-3605-5p	CLIP-seq
MIRT2223130	hsa-miR-3614-5p	CLIP-seq
MIRT2223131	hsa-miR-3616-5p	CLIP-seq
MIRT2223132	hsa-miR-3647-5p	CLIP-seq
MIRT1988718	hsa-miR-383	CLIP-seq
MIRT974475	hsa-miR-3913-5p	CLIP-seq
MIRT974476	hsa-miR-3929	CLIP-seq
MIRT974477	hsa-miR-4284	CLIP-seq
MIRT974478	hsa-miR-4419b	CLIP-seq
MIRT974481	hsa-miR-4433	CLIP-seq
MIRT2223133	hsa-miR-4443	CLIP-seq
MIRT1988721	hsa-miR-4459	CLIP-seq
MIRT974484	hsa-miR-4478	CLIP-seq
MIRT974485	hsa-miR-4530	CLIP-seq
MIRT1988722	hsa-miR-4768-3p	CLIP-seq
MIRT1988723	hsa-miR-4772-5p	CLIP-seq
MIRT2223134	hsa-miR-4795-5p	CLIP-seq
MIRT974491	hsa-miR-485-5p	CLIP-seq
MIRT1988725	hsa-miR-505	CLIP-seq
MIRT2223135	hsa-miR-571	CLIP-seq
MIRT2223136	hsa-miR-573	CLIP-seq
MIRT2223137	hsa-miR-610	CLIP-seq
MIRT974492	hsa-miR-665	CLIP-seq
MIRT2223130	hsa-miR-3614-5p	CLIP-seq
MIRT974481	hsa-miR-4433	CLIP-seq
MIRT1988721	hsa-miR-4459	CLIP-seq
MIRT1988722	hsa-miR-4768-3p	CLIP-seq
MIRT1988725	hsa-miR-505	CLIP-seq
MIRT974468	hsa-miR-2114	CLIP-seq
MIRT974470	hsa-miR-3122	CLIP-seq
MIRT974472	hsa-miR-338-3p	CLIP-seq
MIRT2449028	hsa-miR-3613-3p	CLIP-seq
MIRT2449029	hsa-miR-371-5p	CLIP-seq
MIRT2449030	hsa-miR-371b-5p	CLIP-seq
MIRT974475	hsa-miR-3913-5p	CLIP-seq
MIRT974476	hsa-miR-3929	CLIP-seq
MIRT2449031	hsa-miR-4264	CLIP-seq
MIRT974478	hsa-miR-4419b	CLIP-seq
MIRT974484	hsa-miR-4478	CLIP-seq
MIRT974485	hsa-miR-4530	CLIP-seq
MIRT974486	hsa-miR-4649-3p	CLIP-seq
MIRT974491	hsa-miR-485-5p	CLIP-seq
MIRT2449032	hsa-miR-495	CLIP-seq
MIRT2449033	hsa-miR-622	CLIP-seq
MIRT974468	hsa-miR-2114	CLIP-seq
MIRT974470	hsa-miR-3122	CLIP-seq
MIRT974472	hsa-miR-338-3p	CLIP-seq
MIRT974475	hsa-miR-3913-5p	CLIP-seq
MIRT974476	hsa-miR-3929	CLIP-seq
MIRT974478	hsa-miR-4419b	CLIP-seq
MIRT974484	hsa-miR-4478	CLIP-seq
MIRT974485	hsa-miR-4530	CLIP-seq
MIRT974491	hsa-miR-485-5p	CLIP-seq
MIRT974468	hsa-miR-2114	CLIP-seq
MIRT2527045	hsa-miR-300	CLIP-seq
MIRT974470	hsa-miR-3122	CLIP-seq
MIRT974472	hsa-miR-338-3p	CLIP-seq
MIRT2449028	hsa-miR-3613-3p	CLIP-seq
MIRT2449029	hsa-miR-371-5p	CLIP-seq
MIRT2449030	hsa-miR-371b-5p	CLIP-seq
MIRT2527046	hsa-miR-381	CLIP-seq
MIRT974475	hsa-miR-3913-5p	CLIP-seq
MIRT974476	hsa-miR-3929	CLIP-seq
MIRT2449031	hsa-miR-4264	CLIP-seq
MIRT974478	hsa-miR-4419b	CLIP-seq
MIRT974484	hsa-miR-4478	CLIP-seq
MIRT974485	hsa-miR-4530	CLIP-seq
MIRT974486	hsa-miR-4649-3p	CLIP-seq
MIRT2527047	hsa-miR-4684-5p	CLIP-seq
MIRT974489	hsa-miR-4743	CLIP-seq
MIRT974491	hsa-miR-485-5p	CLIP-seq
MIRT2449032	hsa-miR-495	CLIP-seq
MIRT2527048	hsa-miR-548c-3p	CLIP-seq
MIRT2449033	hsa-miR-622	CLIP-seq
MIRT974468	hsa-miR-2114	CLIP-seq
MIRT2680439	hsa-miR-2276	CLIP-seq
MIRT2527045	hsa-miR-300	CLIP-seq
MIRT974470	hsa-miR-3122	CLIP-seq
MIRT974472	hsa-miR-338-3p	CLIP-seq
MIRT2449028	hsa-miR-3613-3p	CLIP-seq
MIRT2449029	hsa-miR-371-5p	CLIP-seq
MIRT2449030	hsa-miR-371b-5p	CLIP-seq
MIRT2527046	hsa-miR-381	CLIP-seq
MIRT974475	hsa-miR-3913-5p	CLIP-seq
MIRT974476	hsa-miR-3929	CLIP-seq
MIRT2449031	hsa-miR-4264	CLIP-seq
MIRT974478	hsa-miR-4419b	CLIP-seq
MIRT974484	hsa-miR-4478	CLIP-seq
MIRT974485	hsa-miR-4530	CLIP-seq
MIRT974486	hsa-miR-4649-3p	CLIP-seq
MIRT2527047	hsa-miR-4684-5p	CLIP-seq
MIRT974489	hsa-miR-4743	CLIP-seq
MIRT2680440	hsa-miR-4772-3p	CLIP-seq
MIRT974491	hsa-miR-485-5p	CLIP-seq
MIRT2449032	hsa-miR-495	CLIP-seq
MIRT1988725	hsa-miR-505	CLIP-seq
MIRT2527048	hsa-miR-548c-3p	CLIP-seq
MIRT2449033	hsa-miR-622	CLIP-seq

Gene ontology (GO) Show/Hide all (28)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001648	Function	Proteinase-activated receptor activity	IEA
GO:0004435	Function	Phosphatidylinositol-4,5-bisphosphate phospholipase C activity	TAS	9087410
GO:0004930	Function	G protein-coupled receptor activity	IBA
GO:0004930	Function	G protein-coupled receptor activity	IEA
GO:0004930	Function	G protein-coupled receptor activity	TAS
GO:0005515	Function	Protein binding	IPI	16458856, 17474147
GO:0005576	Component	Extracellular region	TAS
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS	9087410
GO:0007165	Process	Signal transduction	IEA
GO:0007186	Process	G protein-coupled receptor signaling pathway	IBA
GO:0007186	Process	G protein-coupled receptor signaling pathway	IEA
GO:0007596	Process	Blood coagulation	IEA
GO:0007596	Process	Blood coagulation	TAS	9087410
GO:0007599	Process	Hemostasis	IEA
GO:0009611	Process	Response to wounding	TAS	9087410
GO:0015057	Function	Thrombin-activated receptor activity	IEA
GO:0015057	Function	Thrombin-activated receptor activity	TAS	9087410
GO:0016020	Component	Membrane	IEA
GO:0016324	Component	Apical plasma membrane	IEA
GO:0030168	Process	Platelet activation	TAS
GO:0032024	Process	Positive regulation of insulin secretion	IEA
GO:0032991	Component	Protein-containing complex	IDA	16458856
GO:0048018	Function	Receptor ligand activity	IEA
GO:0065008	Process	Regulation of biological quality	IEA
GO:0070493	Process	Thrombin-activated receptor signaling pathway	IEA
GO:1990806	Process	Ligand-gated ion channel signaling pathway	IEA

Other IDs

• MIM: 601919
• HGNC: 3539
• e!Ensembl: ENSG00000164220

Protein

• UniProt ID: O00254
• Protein name: Proteinase-activated receptor 3 (PAR-3) (Coagulation factor II receptor-like 2) (Thrombin receptor-like 2)
• Protein function: Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00001	7tm_1	111 → 358	7 transmembrane receptor (rhodopsin family)	Family

• Tissue specificity: TISSUE SPECIFICITY: Highest expression in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut. {ECO:0000269|PubMed:9614115}.
• Sequence:

  MKALIFAAAGLLLLLPTFCQSGMENDTNNLAKPTLPIKTFRGAPPNSFEEFPFSALEGWT
  GATITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGVPANAVTLWMLF
  FRTRSICTTVFYTNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCS
  ILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPFFILKQEYYLVQP
  DITTCHDVHNTCESSSPFQLYYFISLAFFGFLIPFVLIIYCYAAIIRTLNAYDHRWLWYV
  KASLLILVIFTICFAPSNIILIIHHANYYYNNTDGLYFIYLIALCLGSLNSCLDPFLYFL
  MSKTRNHSTAYLTK

• Sequence length: 374

Pathways

KEGG Pathway	Reactome Pathway
Neuroactive ligand-receptor interaction	Peptide ligand-binding receptors
Complement and coagulation cascades	G alpha (q) signalling events
	Thrombin signalling through proteinase activated receptors (PARs)

Related Genes

Sort by: Blended Diseases Pathways Evidence source

F2RL3 4 shared pathwaysComplement and coagulation cascades, Peptide ligand-binding receptors, G alpha (q) signalling events, Thrombin signalling through proteinase activated receptors (PARs) Related via 4 shared pathways including Complement and coagulation cascades, Peptide ligand-binding receptors. PROKR1 2 shared pathwaysPeptide ligand-binding receptors, G alpha (q) signalling events Related via 2 shared pathways including Peptide ligand-binding receptors, G alpha (q) signalling events. UTS2 2 shared pathwaysPeptide ligand-binding receptors, G alpha (q) signalling events Related via 2 shared pathways including Peptide ligand-binding receptors, G alpha (q) signalling events. PROKR2 2 shared pathwaysPeptide ligand-binding receptors, G alpha (q) signalling events Related via 2 shared pathways including Peptide ligand-binding receptors, G alpha (q) signalling events. NTSR2 2 shared pathwaysPeptide ligand-binding receptors, G alpha (q) signalling events Related via 2 shared pathways including Peptide ligand-binding receptors, G alpha (q) signalling events.

Related Gene	Shared Diseases	Shared Disease Names	Shared Pathways	Shared Pathway Names	Shared Evidence Sources	Shared Evidence Names
F2RL3	0	[]	4	["Complement and coagulation cascades","Peptide ligand-binding receptors","G alpha (q) signalling events","Thrombin signalling through proteinase activated receptors (PARs)"]	0	[]
PROKR1	0	[]	2	["Peptide ligand-binding receptors","G alpha (q) signalling events"]	0	[]
UTS2	0	[]	2	["Peptide ligand-binding receptors","G alpha (q) signalling events"]	0	[]
PROKR2	0	[]	2	["Peptide ligand-binding receptors","G alpha (q) signalling events"]	0	[]
NTSR2	0	[]	2	["Peptide ligand-binding receptors","G alpha (q) signalling events"]	0	[]

Diseases Linked via Similar Genes

Stroke Linked via 2 of 5 related genesPROKR1, NTSR2 Cholelithiasis Linked via 1 of 5 related genesF2RL3 Peliosis hepatis Linked via 1 of 5 related genesF2RL3 Hirschsprung disease Linked via 1 of 5 related genesPROKR1 Hyperalgesia Linked via 1 of 5 related genesPROKR1

Disease	Linked Via (Gene Count)	Linked Via (Gene Names)
Stroke	2	["PROKR1","NTSR2"]
Cholelithiasis	1	["F2RL3"]
Peliosis hepatis	1	["F2RL3"]
Hirschsprung disease	1	["PROKR1"]
Hyperalgesia	1	["PROKR1"]