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Gene Gene information from NCBI Gene database.
Entrez ID 51290
Gene name ERGIC and golgi 2
Gene symbol ERGIC2
Synonyms (NCBI Gene)
CDA14Erv41PTX1cd002
Chromosome 12
Chromosome location 12p11.22
Summary ERGIC2, or PTX1, is a ubiquitously expressed nuclear protein that is downregulated in prostate carcinoma (Kwok et al., 2001 [PubMed 11445006]).[supplied by OMIM, Aug 2008]
miRNA miRNA information provided by mirtarbase database.
379 Show/Hide all (379)
miRTarBase ID miRNA Experiments Reference
MIRT027760 hsa-miR-98-5p Microarray 19088304
MIRT028384 hsa-miR-32-5p Sequencing 20371350
MIRT032433 hsa-let-7b-5p Proteomics 18668040
MIRT049453 hsa-miR-92a-3p CLASH 23622248
MIRT037771 hsa-miR-671-3p CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
24 Show/Hide all (24)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 17980171, 28514442, 31142615, 33961781
GO:0005634 Component Nucleus IDA 17980171
GO:0005634 Component Nucleus IEA
GO:0005730 Component Nucleolus IDA
GO:0005737 Component Cytoplasm IDA 17980171
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
612236 30208 ENSG00000087502
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q96RQ1
Protein name Endoplasmic reticulum-Golgi intermediate compartment protein 2
Protein function Possible role in transport between endoplasmic reticulum and Golgi.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07970 COPIIcoated_ERV 157 → 333 Endoplasmic reticulum vesicle transporter Family
PF13850 ERGIC_N 13 → 101 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Domain
Tissue specificity TISSUE SPECIFICITY: Ubiquitously expressed. {ECO:0000269|PubMed:11445006}.
Sequence
Sequence length 377
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Reference Evidence Score
EBV-positive nodal T- and NK-cell lymphoma Likely benign ClinVar —
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Show/Hide Text Mining Associations (11)
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Adenoma Adenoma BEFREE 11048804
★★★★★
★☆☆☆☆
Found in Text Mining only
Colitis Colitis BEFREE 30504685
★★★★★
★☆☆☆☆
Found in Text Mining only
Developmental Disabilities Developmental disability Pubtator 37563198 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Kallmann Syndrome Kallmann syndrome Pubtator 37563198 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Malignant neoplasm of prostate Prostate cancer BEFREE 11445006, 12932305, 16989575
★★★★★
★☆☆☆☆
Found in Text Mining only
Mandibulofacial Dysostosis Mandibulofacial Dysostosis BEFREE 9337397
★★★★★
★☆☆☆☆
Found in Text Mining only
Paroxysmal nocturnal hemoglobinuria Paroxysmal nocturnal hemoglobinuria BEFREE 2462937
★★★★★
★☆☆☆☆
Found in Text Mining only
Prostate carcinoma Prostate cancer BEFREE 11445006, 12932305, 16989575
★★★★★
★☆☆☆☆
Found in Text Mining only
Prostatic Neoplasms Prostatic Neoplasms BEFREE 12932305
★★★★★
★☆☆☆☆
Found in Text Mining only
Prostatic Neoplasms Prostatic Neoplasms LHGDN 16989575
★★★★★
★☆☆☆☆
Found in Text Mining only