Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	377841
Gene name	Ectonucleoside triphosphate diphosphohydrolase 8
Gene symbol	ENTPD8
Synonyms (NCBI Gene)	E-NTPDaseGLSR2492NTPDase-8UNQ2492
Chromosome	9
Chromosome location	9q34.3

48 Show/Hide all (48)

miRTarBase ID	miRNA	Experiments
MIRT964913	hsa-miR-1254	CLIP-seq
MIRT964914	hsa-miR-146b-3p	CLIP-seq
MIRT964915	hsa-miR-214	CLIP-seq
MIRT964916	hsa-miR-3116	CLIP-seq
MIRT964917	hsa-miR-3173-5p	CLIP-seq
MIRT964918	hsa-miR-338-3p	CLIP-seq
MIRT964919	hsa-miR-3619-5p	CLIP-seq
MIRT964920	hsa-miR-3622a-3p	CLIP-seq
MIRT964921	hsa-miR-3622b-3p	CLIP-seq
MIRT964922	hsa-miR-3664-3p	CLIP-seq
MIRT964923	hsa-miR-3689d	CLIP-seq
MIRT964924	hsa-miR-377	CLIP-seq
MIRT964925	hsa-miR-4254	CLIP-seq
MIRT964926	hsa-miR-4270	CLIP-seq
MIRT964927	hsa-miR-4308	CLIP-seq
MIRT964928	hsa-miR-4441	CLIP-seq
MIRT964929	hsa-miR-4497	CLIP-seq
MIRT964930	hsa-miR-4530	CLIP-seq
MIRT964931	hsa-miR-4687-3p	CLIP-seq
MIRT964932	hsa-miR-4781-5p	CLIP-seq
MIRT964933	hsa-miR-4787-5p	CLIP-seq
MIRT964934	hsa-miR-615-5p	CLIP-seq
MIRT964935	hsa-miR-671-5p	CLIP-seq
MIRT964936	hsa-miR-761	CLIP-seq
MIRT964937	hsa-miR-766	CLIP-seq
MIRT964938	hsa-miR-873	CLIP-seq
MIRT964939	hsa-miR-874	CLIP-seq
MIRT964914	hsa-miR-146b-3p	CLIP-seq
MIRT964917	hsa-miR-3173-5p	CLIP-seq
MIRT964920	hsa-miR-3622a-3p	CLIP-seq
MIRT964921	hsa-miR-3622b-3p	CLIP-seq
MIRT964923	hsa-miR-3689d	CLIP-seq
MIRT964925	hsa-miR-4254	CLIP-seq
MIRT964927	hsa-miR-4308	CLIP-seq
MIRT964931	hsa-miR-4687-3p	CLIP-seq
MIRT964939	hsa-miR-874	CLIP-seq
MIRT2220406	hsa-miR-3620	CLIP-seq
MIRT2448894	hsa-miR-1291	CLIP-seq
MIRT964927	hsa-miR-4308	CLIP-seq
MIRT964935	hsa-miR-671-5p	CLIP-seq
MIRT2524227	hsa-miR-103a	CLIP-seq
MIRT2524228	hsa-miR-107	CLIP-seq
MIRT2448894	hsa-miR-1291	CLIP-seq
MIRT964917	hsa-miR-3173-5p	CLIP-seq
MIRT2524229	hsa-miR-328	CLIP-seq
MIRT2524230	hsa-miR-4514	CLIP-seq
MIRT2524231	hsa-miR-4692	CLIP-seq
MIRT2524232	hsa-miR-663b	CLIP-seq

18 Show/Hide all (18)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0004050	Function	Apyrase activity	IEA
GO:0004382	Function	GDP phosphatase activity	IBA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005524	Function	ATP binding	IEA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0009124	Process	Nucleoside monophosphate biosynthetic process	IEA
GO:0009133	Process	Nucleoside diphosphate biosynthetic process	IEA
GO:0009134	Process	Nucleoside diphosphate catabolic process	IBA
GO:0016020	Component	Membrane	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0017110	Function	Nucleoside diphosphate phosphatase activity	IEA
GO:0017111	Function	Ribonucleoside triphosphate phosphatase activity	IBA
GO:0017111	Function	Ribonucleoside triphosphate phosphatase activity	IEA
GO:0045134	Function	UDP phosphatase activity	IBA
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
616748	24860	ENSG00000188833

Q5MY95

Protein name

Ectonucleoside triphosphate diphosphohydrolase 8 (E-NTPDase 8) (NTPDase 8) (NTPDase8) (EC 3.6.1.5)

Protein function

Canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. Ectonucleoside NTPDases catalyze the hydrolysis of gamma- and beta-phosphate residues of nucleotides, playing a central role in concentration of extracellular

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01150	GDA1_CD39	34 → 462	GDA1/CD39 (nucleoside phosphatase) family	Family

Sequence

MGLSRKEQVFLALLGASGVSGLTALILLLVEATSVLLPTDIKFGIVFDAGSSHTSLFLYQ
WLANKENGTGVVSQALACQVEGPGISSYTSNAAQAGESLQGCLEEALVLIPEAQHRKTPT
FLGATAGMRLLSRKNSSQARDIFAAVTQVLGRSPVDFWGAELLAGQAEGAFGWITVNYGL
GTLVKYSFTGEWIQPPEEMLVGALDMGGASTQITFVPGGPILDKSTQADFRLYGSDYSVY
THSYLCFGRDQMLSRLLVGLVQSRPAALLRHPCYLSGYQTTLALGPLYESPCVHATPPLS
LPQNLTVEGTGNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPLRGQFYAFSNFYYTFH
FLNLTSRQPLSTVNATIWEFCQRPWKLVEASYPGQDRWLRDYCASGLYILTLLHEGYGFS
EETWPSLEFRKQAGGVDIGWTLGYMLNLTGMIPADAPAQWRAESYGVWVAKVVFMVLALV
AVVGAALVQLFWLQD

Sequence length

495

Interactions

View interactions

KEGG Pathway	Reactome Pathway
Purine metabolism	Phosphate bond hydrolysis by NTPDase proteins
Pyrimidine metabolism
Metabolic pathways
Nucleotide metabolism
Epstein-Barr virus infection

ENTPD8 (ectonucleoside triphosphate diphosphohydrolase 8)

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