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Gene Gene information from NCBI Gene database.
Entrez ID 56851
Gene name ER membrane protein complex subunit 7
Gene symbol EMC7
Synonyms (NCBI Gene)
C11orf3C15orf24HT022ORF1-FL1
Chromosome 15
Chromosome location 15q14
miRNA miRNA information provided by mirtarbase database.
353 Show/Hide all (353)
miRTarBase ID miRNA Experiments Reference
MIRT024416 hsa-miR-215-5p Microarray 19074876
MIRT026662 hsa-miR-192-5p Microarray 19074876
MIRT029673 hsa-miR-26b-5p Microarray 19088304
MIRT621135 hsa-miR-646 HITS-CLIP 19536157
MIRT621134 hsa-miR-1207-3p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
17 Show/Hide all (17)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 28514442, 28734904, 31286866, 32296183, 33961781
GO:0005783 Component Endoplasmic reticulum IEA
GO:0005789 Component Endoplasmic reticulum membrane IDA 32439656
GO:0005789 Component Endoplasmic reticulum membrane IEA
GO:0005789 Component Endoplasmic reticulum membrane NAS 29242231
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
620631 24301 ENSG00000134153
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9NPA0
Protein name Endoplasmic reticulum membrane protein complex subunit 7 (ER membrane protein complex subunit 7)
Protein function Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins (PubMed:29242231, PubMed:29809151, PubMed:30415835, PubMed
PDB 1B0G , 1LP9 , 2J8U , 2JCC , 2UWE , 6WW7 , 6Z3W , 7ADO , 8EOI , 8J0N , 8J0O , 8S9S , 9C7V
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF09430 DUF2012 56 → 168 Protein of unknown function (DUF2012) Family
Sequence
MAAALWGFFPVLLLLLLSGDVQSSEVPGAAAEGSGGSGVGIGDRFKIEGRAVVPGVKPQD
WISAARVLVDGEEHVGFLKTDGSFVVHDIPSGSYVVEVVSPAYRFDPVRVDITSKGKMRA
RYVNYIKTSEVVRLPYPLQMKSSGPPSYFIKRESWGWTDFLMNPMVMM
MVLPLLIFVLLP
KVVNTSDPDMRREMEQSMNMLNSNHELPDVSEFMTRLFSSKSSGKSSSGSSKTGKSGAGK
RR
Sequence length 242
Interactions View interactions