EIF3CL (eukaryotic translation initiation factor 3 subunit C like)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 728689
• Gene name: Eukaryotic translation initiation factor 3 subunit C like
• Gene symbol: EIF3CL
• Synonyms (NCBI Gene): -
• Chromosome: 16
• Chromosome location: 16p12.1
• Summary: The protein encoded by this gene is a core subunit of the eukaryotic translation initiation factor 3 (eIF3) complex. The encoded protein is nearly identical to another protein, eIF3c, from a related gene. The eIF3 complex binds the 40S ribosome and mRNAs

miRNA Show/Hide all (88)

miRTarBase ID	miRNA	Experiments	Reference
MIRT020588	hsa-miR-155-5p	Proteomics	18668040
MIRT031545	hsa-miR-16-5p	Proteomics	18668040
MIRT454032	hsa-miR-3937	PAR-CLIP	23592263
MIRT454031	hsa-miR-3136-3p	PAR-CLIP	23592263
MIRT454030	hsa-miR-7155-3p	PAR-CLIP	23592263
MIRT454031	hsa-miR-3136-3p	PAR-CLIP	26701625
MIRT454032	hsa-miR-3937	PAR-CLIP	26701625
MIRT454030	hsa-miR-7155-3p	PAR-CLIP	26701625
MIRT454032	hsa-miR-3937	PAR-CLIP	23592263
MIRT454031	hsa-miR-3136-3p	PAR-CLIP	23592263
MIRT454030	hsa-miR-7155-3p	PAR-CLIP	23592263
MIRT957541	hsa-miR-1193	CLIP-seq
MIRT957542	hsa-miR-1273g	CLIP-seq
MIRT957543	hsa-miR-134	CLIP-seq
MIRT957544	hsa-miR-185	CLIP-seq
MIRT957545	hsa-miR-299-5p	CLIP-seq
MIRT957546	hsa-miR-3117-3p	CLIP-seq
MIRT957547	hsa-miR-3118	CLIP-seq
MIRT957548	hsa-miR-3136-5p	CLIP-seq
MIRT957549	hsa-miR-3169	CLIP-seq
MIRT957550	hsa-miR-3591-5p	CLIP-seq
MIRT957551	hsa-miR-3606	CLIP-seq
MIRT957552	hsa-miR-4261	CLIP-seq
MIRT957553	hsa-miR-4306	CLIP-seq
MIRT957554	hsa-miR-4439	CLIP-seq
MIRT957555	hsa-miR-4513	CLIP-seq
MIRT957556	hsa-miR-4644	CLIP-seq
MIRT957557	hsa-miR-4759	CLIP-seq
MIRT957558	hsa-miR-4761-5p	CLIP-seq
MIRT957559	hsa-miR-4797-5p	CLIP-seq
MIRT957560	hsa-miR-651	CLIP-seq
MIRT957561	hsa-miR-759	CLIP-seq
MIRT957562	hsa-miR-921	CLIP-seq
MIRT957541	hsa-miR-1193	CLIP-seq
MIRT957542	hsa-miR-1273g	CLIP-seq
MIRT957545	hsa-miR-299-5p	CLIP-seq
MIRT957546	hsa-miR-3117-3p	CLIP-seq
MIRT957549	hsa-miR-3169	CLIP-seq
MIRT957552	hsa-miR-4261	CLIP-seq
MIRT957557	hsa-miR-4759	CLIP-seq
MIRT957558	hsa-miR-4761-5p	CLIP-seq
MIRT957559	hsa-miR-4797-5p	CLIP-seq
MIRT957560	hsa-miR-651	CLIP-seq
MIRT957561	hsa-miR-759	CLIP-seq
MIRT957541	hsa-miR-1193	CLIP-seq
MIRT957542	hsa-miR-1273g	CLIP-seq
MIRT957543	hsa-miR-134	CLIP-seq
MIRT957545	hsa-miR-299-5p	CLIP-seq
MIRT957546	hsa-miR-3117-3p	CLIP-seq
MIRT957547	hsa-miR-3118	CLIP-seq
MIRT957548	hsa-miR-3136-5p	CLIP-seq
MIRT957549	hsa-miR-3169	CLIP-seq
MIRT957550	hsa-miR-3591-5p	CLIP-seq
MIRT957551	hsa-miR-3606	CLIP-seq
MIRT957554	hsa-miR-4439	CLIP-seq
MIRT957555	hsa-miR-4513	CLIP-seq
MIRT957557	hsa-miR-4759	CLIP-seq
MIRT957558	hsa-miR-4761-5p	CLIP-seq
MIRT957560	hsa-miR-651	CLIP-seq
MIRT957562	hsa-miR-921	CLIP-seq
MIRT957541	hsa-miR-1193	CLIP-seq
MIRT957542	hsa-miR-1273g	CLIP-seq
MIRT957544	hsa-miR-185	CLIP-seq
MIRT957545	hsa-miR-299-5p	CLIP-seq
MIRT957546	hsa-miR-3117-3p	CLIP-seq
MIRT957549	hsa-miR-3169	CLIP-seq
MIRT957552	hsa-miR-4261	CLIP-seq
MIRT957553	hsa-miR-4306	CLIP-seq
MIRT957556	hsa-miR-4644	CLIP-seq
MIRT957557	hsa-miR-4759	CLIP-seq
MIRT957558	hsa-miR-4761-5p	CLIP-seq
MIRT957559	hsa-miR-4797-5p	CLIP-seq
MIRT957560	hsa-miR-651	CLIP-seq
MIRT957561	hsa-miR-759	CLIP-seq
MIRT957541	hsa-miR-1193	CLIP-seq
MIRT957542	hsa-miR-1273g	CLIP-seq
MIRT957544	hsa-miR-185	CLIP-seq
MIRT957545	hsa-miR-299-5p	CLIP-seq
MIRT957546	hsa-miR-3117-3p	CLIP-seq
MIRT957549	hsa-miR-3169	CLIP-seq
MIRT957552	hsa-miR-4261	CLIP-seq
MIRT957553	hsa-miR-4306	CLIP-seq
MIRT957556	hsa-miR-4644	CLIP-seq
MIRT957557	hsa-miR-4759	CLIP-seq
MIRT957558	hsa-miR-4761-5p	CLIP-seq
MIRT957559	hsa-miR-4797-5p	CLIP-seq
MIRT957560	hsa-miR-651	CLIP-seq
MIRT957561	hsa-miR-759	CLIP-seq

Gene ontology (GO) Show/Hide all (16)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001732	Process	Formation of cytoplasmic translation initiation complex	IEA
GO:0002183	Process	Cytoplasmic translational initiation	IEA
GO:0003723	Function	RNA binding	IEA
GO:0003743	Function	Translation initiation factor activity	IBA
GO:0003743	Function	Translation initiation factor activity	IEA
GO:0005515	Function	Protein binding	IPI	28514442, 30021884, 33961781
GO:0005737	Component	Cytoplasm	IEA
GO:0005852	Component	Eukaryotic translation initiation factor 3 complex	IBA
GO:0005852	Component	Eukaryotic translation initiation factor 3 complex	IEA
GO:0006412	Process	Translation	IEA
GO:0006413	Process	Translational initiation	IBA
GO:0006413	Process	Translational initiation	IEA
GO:0016282	Component	Eukaryotic 43S preinitiation complex	IEA
GO:0031369	Function	Translation initiation factor binding	IBA
GO:0031369	Function	Translation initiation factor binding	IEA
GO:0033290	Component	Eukaryotic 48S preinitiation complex	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: B5ME19
• Protein name: Eukaryotic translation initiation factor 3 subunit C-like protein
• Protein function: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1,
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01399	PCI	713 → 847	PCI domain	Domain
  PF05470	eIF-3c_N	29 → 706	Eukaryotic translation initiation factor 3 subunit 8 N-terminus	Family

• Sequence:

  MSRFFTTGSDSESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEEL
  TNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNEL
  WEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEG
  SSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDS
  DSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEEDNEGG
  EWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQ
  IAAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIF
  VGENILEESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQV
  CAIIERVQRYLEEKGTTEEVCRIYLLRILHTYYKFDYKAHQRQLTPPEGSSKSEQDQAEN
  EGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQ
  HADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERN
  QEQEKVERRRQVPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMISKQFHHQLR
  VGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTML
  VRKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPT
  QTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQGTYGGYFRDQKDGYRKNEGYM
  RRGGYRQQQSQTAY

• Sequence length: 914

Related Genes

No strongly related genes found yet for EIF3CL.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to EIF3CL.