EFCAB5 (EF-hand calcium binding domain 5)

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Gene miRNA Gene ontology Other IDs Protein Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 374786
• Gene name: EF-hand calcium binding domain 5
• Gene symbol: EFCAB5
• Synonyms (NCBI Gene): -
• Chromosome: 17
• Chromosome location: 17q11.2

miRNA Show/Hide all (91)

miRTarBase ID	miRNA	Experiments	Reference
MIRT017332	hsa-miR-335-5p	Microarray	18185580
MIRT514669	hsa-miR-3922-5p	PAR-CLIP	23446348
MIRT514670	hsa-miR-1225-3p	PAR-CLIP	23446348
MIRT514668	hsa-miR-1233-3p	PAR-CLIP	23446348
MIRT514666	hsa-miR-6894-5p	PAR-CLIP	23446348
MIRT514667	hsa-miR-7106-5p	PAR-CLIP	23446348
MIRT514665	hsa-miR-561-5p	PAR-CLIP	23446348
MIRT514664	hsa-miR-6807-5p	PAR-CLIP	23446348
MIRT514663	hsa-miR-1273e	PAR-CLIP	23446348
MIRT514669	hsa-miR-3922-5p	PAR-CLIP	23446348
MIRT514670	hsa-miR-1225-3p	PAR-CLIP	23446348
MIRT514668	hsa-miR-1233-3p	PAR-CLIP	23446348
MIRT514666	hsa-miR-6894-5p	PAR-CLIP	23446348
MIRT514667	hsa-miR-7106-5p	PAR-CLIP	23446348
MIRT514665	hsa-miR-561-5p	PAR-CLIP	23446348
MIRT514664	hsa-miR-6807-5p	PAR-CLIP	23446348
MIRT514663	hsa-miR-1273e	PAR-CLIP	23446348
MIRT953633	hsa-miR-150	CLIP-seq
MIRT953634	hsa-miR-3197	CLIP-seq
MIRT953635	hsa-miR-4649-3p	CLIP-seq
MIRT953636	hsa-miR-4663	CLIP-seq
MIRT953637	hsa-miR-4713-5p	CLIP-seq
MIRT953638	hsa-miR-4728-3p	CLIP-seq
MIRT953639	hsa-miR-532-3p	CLIP-seq
MIRT953640	hsa-miR-129-5p	CLIP-seq
MIRT1982345	hsa-miR-3074-5p	CLIP-seq
MIRT1982346	hsa-miR-3545-3p	CLIP-seq
MIRT1982347	hsa-miR-4666-3p	CLIP-seq
MIRT1982348	hsa-miR-4680-5p	CLIP-seq
MIRT1982349	hsa-miR-4722-3p	CLIP-seq
MIRT1982350	hsa-miR-485-3p	CLIP-seq
MIRT1982351	hsa-miR-630	CLIP-seq
MIRT1982352	hsa-miR-664	CLIP-seq
MIRT2217148	hsa-miR-1233	CLIP-seq
MIRT2217149	hsa-miR-1321	CLIP-seq
MIRT2217150	hsa-miR-3122	CLIP-seq
MIRT2217151	hsa-miR-3173-3p	CLIP-seq
MIRT953634	hsa-miR-3197	CLIP-seq
MIRT2217152	hsa-miR-3689a-3p	CLIP-seq
MIRT2217153	hsa-miR-3689c	CLIP-seq
MIRT2217154	hsa-miR-3913-5p	CLIP-seq
MIRT2217155	hsa-miR-3942-5p	CLIP-seq
MIRT2217156	hsa-miR-3975	CLIP-seq
MIRT2217157	hsa-miR-4419a	CLIP-seq
MIRT2217158	hsa-miR-4428	CLIP-seq
MIRT2217159	hsa-miR-4510	CLIP-seq
MIRT2217160	hsa-miR-4521	CLIP-seq
MIRT953635	hsa-miR-4649-3p	CLIP-seq
MIRT953636	hsa-miR-4663	CLIP-seq
MIRT1982347	hsa-miR-4666-3p	CLIP-seq
MIRT2217161	hsa-miR-4703-5p	CLIP-seq
MIRT2217162	hsa-miR-4728-5p	CLIP-seq
MIRT2217163	hsa-miR-4739	CLIP-seq
MIRT2217164	hsa-miR-4756-5p	CLIP-seq
MIRT2217165	hsa-miR-4779	CLIP-seq
MIRT1982350	hsa-miR-485-3p	CLIP-seq
MIRT2217166	hsa-miR-510	CLIP-seq
MIRT2217167	hsa-miR-512-5p	CLIP-seq
MIRT2217168	hsa-miR-545	CLIP-seq
MIRT1982351	hsa-miR-630	CLIP-seq
MIRT1982352	hsa-miR-664	CLIP-seq
MIRT2521209	hsa-miR-1283	CLIP-seq
MIRT2521210	hsa-miR-1285	CLIP-seq
MIRT2521211	hsa-miR-3187-5p	CLIP-seq
MIRT2521212	hsa-miR-3194-5p	CLIP-seq
MIRT2521213	hsa-miR-3677-5p	CLIP-seq
MIRT2521214	hsa-miR-4435	CLIP-seq
MIRT2521215	hsa-miR-4684-5p	CLIP-seq
MIRT2521216	hsa-miR-4710	CLIP-seq
MIRT2521217	hsa-miR-4786-5p	CLIP-seq
MIRT2521218	hsa-miR-4792	CLIP-seq
MIRT2521219	hsa-miR-561	CLIP-seq
MIRT2521220	hsa-miR-593	CLIP-seq
MIRT2521221	hsa-miR-612	CLIP-seq
MIRT2521222	hsa-miR-661	CLIP-seq
MIRT2521223	hsa-miR-769-5p	CLIP-seq
MIRT2521209	hsa-miR-1283	CLIP-seq
MIRT2521210	hsa-miR-1285	CLIP-seq
MIRT2521211	hsa-miR-3187-5p	CLIP-seq
MIRT2521212	hsa-miR-3194-5p	CLIP-seq
MIRT2521213	hsa-miR-3677-5p	CLIP-seq
MIRT2521214	hsa-miR-4435	CLIP-seq
MIRT2521215	hsa-miR-4684-5p	CLIP-seq
MIRT2521216	hsa-miR-4710	CLIP-seq
MIRT2521217	hsa-miR-4786-5p	CLIP-seq
MIRT2521218	hsa-miR-4792	CLIP-seq
MIRT2521219	hsa-miR-561	CLIP-seq
MIRT2521220	hsa-miR-593	CLIP-seq
MIRT2521221	hsa-miR-612	CLIP-seq
MIRT2521222	hsa-miR-661	CLIP-seq
MIRT2521223	hsa-miR-769-5p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005509	Function	Calcium ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: A4FU69
• Protein name: EF-hand calcium-binding domain-containing protein 5
• Sequence:

  MNESASQEELRPAQENRKEDKERKWNLTEVKELHETLQSVPDVPVKEDTNSVVEKAMDEI
  KSQELNLEGQRKISPGSIKDSKTEASGNIAIRKSAKVIFALDETELKSKPEHTWKKNLFE
  RMEARAQAMQQKIIDKENLKKELEKKAEKKLPRDNLAKEWFNTDSMTLNNTAYLLDKLLP
  TLVPGVENMLTQVEKKKVLTEADTPSKFDPINYLGEYLIRNNPNYIKDPGMSGYQRLMKE
  VTEDLKIYVPDTICNRVSKMKENVKQNRKQRESIDKIIVKVANTRKQALQEQFDEWILDP
  KGMIPKSVIQNVLQEFFQNPDFKLGSHCKQLDITDSTEPRLNKMEFTEYISSHIKDLKSE
  MFEELLKHLCHSADEFREVIKADMRRQMFAELFLHCDHGKVGFLDRQRTLALLELFYDHS
  SQMLRSLLRNPRQWPFIEFEEINLTELWGDMDNQKHIYEGFDKVLLEMNTLLSANHASKT
  QSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQGKKPTAEQELYI
  ESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSR
  ESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSLRESVIEEPYQKSEQGPYGEII
  SEEQEDIGSTSQSRKDSILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSELQEE
  VPTLSRKDHFPETTKKEVQKDKPCEPKSQKIEGKSWSGEFFTCNWKMKYVTFEDEEQANL
  IYGNSRFTDLHSIIRNIQSCKEVKGRTAFNGVSFNLLQFVQLLETFVGEDAPLSVSETLT
  SFFKEGYVETEQEKMNALEQFSQNAFQVRQRLLLEAIFQKWDSDGSGFLDLKEVDELLYT
  YKEGMEKESMKKAKLHIQFPKPHPGHEVRLSSKQFQNYIELVVSELRGNEDQVLESVVEF
  LMNALERSHIESLRNSARRKWLHQIQCAAETSGVSLEPVYSETFKALMQDAEAHGNKKIS
  AHISLLEENLLLPEKGNVLLRNVACTLDDAQFVLNRVLYRDMKGISFTVVDEGKPIHVPQ
  VQYHGNIFFWNQSRNKHDYNGSFLALPLQDAYMRIFGVLAVDTLRDPHEINIFLPHEIRF
  YQGVANVFSTAYHYVHSREHILHIVITGIGWLYDVTSSITSITTYFVEPSPAQDSDYVLR
  NMMVTGQLGLTEIHKNPPTIHRKSCIFRDFLFKCTDSSEVVLASACGETHIVVPLRERTG
  EALGVLDFNIGQNRMLLCQEYKDLQKMMKVVQVACYEILGEFSGEIKKKYILEIENVREV
  QRAGILFFRIMLLELQESIQLLNSMEFVSLLLYDHTLVTEPNSPQDSKSMELEANVKLVR
  DILKAVILFFHPELEFSSDFGSWDKCKFYVNKYLVNNICAFDPTAKHVEVNVQLIDEYIR
  DHSRTEVWKFGNVVIEHLYHWIHICSALMKITKQLNSGITPPLPSKTDNYMYAKMPGEGL
  QEK

• Sequence length: 1503

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations Show/Hide Unknown Diseases (6)
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
CHRONIC OBSTRUCTIVE PULMONARY DISEASE	—	GWAS catalog	30804561, 33106845, 33909500	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
EBV-positive nodal T- and NK-cell lymphoma	Likely benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
EFCAB5-related disorder	Likely benign; Benign; Uncertain significance	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of esophagus	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of urinary bladder	Likely benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thymoma	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Autism Spectrum Disorders	Autism Spectrum Disorder	BEFREE	26189338		★☆☆☆☆ Found in Text Mining only
Chronic Obstructive Airway Disease	Chronic Obstructive Pulmonary Disease	GWASCAT_DG	30804561		★☆☆☆☆ Found in Text Mining only

Related Genes

No strongly related genes found yet for EFCAB5.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to EFCAB5.