DTD2 (D-aminoacyl-tRNA deacylase 2)

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Gene miRNA Gene ontology Other IDs Protein Diseases linked via similar genes

Gene

• Entrez ID: 112487
• Gene name: D-aminoacyl-tRNA deacylase 2
• Gene symbol: DTD2
• Synonyms (NCBI Gene): ATD, C14orf126
• Chromosome: 14
• Chromosome location: 14q12

miRNA Show/Hide all (81)

miRTarBase ID	miRNA	Experiments	Reference
MIRT047238	hsa-miR-181b-5p	CLASH	23622248
MIRT685119	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT685118	hsa-miR-6893-5p	HITS-CLIP	23313552
MIRT685117	hsa-miR-940	HITS-CLIP	23313552
MIRT685116	hsa-miR-3929	HITS-CLIP	23313552
MIRT685115	hsa-miR-4419b	HITS-CLIP	23313552
MIRT685114	hsa-miR-4478	HITS-CLIP	23313552
MIRT685113	hsa-miR-4768-3p	HITS-CLIP	23313552
MIRT685112	hsa-miR-4459	HITS-CLIP	23313552
MIRT685111	hsa-miR-665	HITS-CLIP	23313552
MIRT685110	hsa-miR-4649-3p	HITS-CLIP	23313552
MIRT685109	hsa-miR-1827	HITS-CLIP	23313552
MIRT685108	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT685107	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT685106	hsa-miR-4722-5p	HITS-CLIP	23313552
MIRT685105	hsa-miR-7160-5p	HITS-CLIP	23313552
MIRT685104	hsa-miR-7106-5p	HITS-CLIP	23313552
MIRT685103	hsa-miR-149-3p	HITS-CLIP	23313552
MIRT685102	hsa-miR-4728-5p	HITS-CLIP	23313552
MIRT685101	hsa-miR-6785-5p	HITS-CLIP	23313552
MIRT685100	hsa-miR-6883-5p	HITS-CLIP	23313552
MIRT685099	hsa-miR-6799-5p	HITS-CLIP	23313552
MIRT685098	hsa-miR-30c-1-3p	HITS-CLIP	23313552
MIRT685097	hsa-miR-30c-2-3p	HITS-CLIP	23313552
MIRT685096	hsa-miR-6788-5p	HITS-CLIP	23313552
MIRT685095	hsa-miR-1273h-5p	HITS-CLIP	23313552
MIRT685094	hsa-miR-30b-3p	HITS-CLIP	23313552
MIRT685093	hsa-miR-3689a-3p	HITS-CLIP	23313552
MIRT685092	hsa-miR-3689b-3p	HITS-CLIP	23313552
MIRT685091	hsa-miR-3689c	HITS-CLIP	23313552
MIRT685090	hsa-miR-6779-5p	HITS-CLIP	23313552
MIRT685089	hsa-miR-6780a-5p	HITS-CLIP	23313552
MIRT685088	hsa-miR-887-5p	HITS-CLIP	23313552
MIRT630481	hsa-miR-6089	HITS-CLIP	23824327
MIRT630480	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT630479	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT630478	hsa-miR-6847-3p	HITS-CLIP	23824327
MIRT630477	hsa-miR-564	HITS-CLIP	23824327
MIRT630476	hsa-miR-4284	HITS-CLIP	23824327
MIRT630475	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT630474	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT685119	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT685118	hsa-miR-6893-5p	HITS-CLIP	23313552
MIRT685117	hsa-miR-940	HITS-CLIP	23313552
MIRT685116	hsa-miR-3929	HITS-CLIP	23313552
MIRT685115	hsa-miR-4419b	HITS-CLIP	23313552
MIRT685114	hsa-miR-4478	HITS-CLIP	23313552
MIRT685113	hsa-miR-4768-3p	HITS-CLIP	23313552
MIRT685112	hsa-miR-4459	HITS-CLIP	23313552
MIRT685111	hsa-miR-665	HITS-CLIP	23313552
MIRT685110	hsa-miR-4649-3p	HITS-CLIP	23313552
MIRT685109	hsa-miR-1827	HITS-CLIP	23313552
MIRT685108	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT685107	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT685106	hsa-miR-4722-5p	HITS-CLIP	23313552
MIRT685105	hsa-miR-7160-5p	HITS-CLIP	23313552
MIRT685104	hsa-miR-7106-5p	HITS-CLIP	23313552
MIRT685103	hsa-miR-149-3p	HITS-CLIP	23313552
MIRT685102	hsa-miR-4728-5p	HITS-CLIP	23313552
MIRT685101	hsa-miR-6785-5p	HITS-CLIP	23313552
MIRT685100	hsa-miR-6883-5p	HITS-CLIP	23313552
MIRT685099	hsa-miR-6799-5p	HITS-CLIP	23313552
MIRT685098	hsa-miR-30c-1-3p	HITS-CLIP	23313552
MIRT685097	hsa-miR-30c-2-3p	HITS-CLIP	23313552
MIRT685096	hsa-miR-6788-5p	HITS-CLIP	23313552
MIRT685095	hsa-miR-1273h-5p	HITS-CLIP	23313552
MIRT685094	hsa-miR-30b-3p	HITS-CLIP	23313552
MIRT685093	hsa-miR-3689a-3p	HITS-CLIP	23313552
MIRT685092	hsa-miR-3689b-3p	HITS-CLIP	23313552
MIRT685091	hsa-miR-3689c	HITS-CLIP	23313552
MIRT685090	hsa-miR-6779-5p	HITS-CLIP	23313552
MIRT685089	hsa-miR-6780a-5p	HITS-CLIP	23313552
MIRT685088	hsa-miR-887-5p	HITS-CLIP	23313552
MIRT630481	hsa-miR-6089	HITS-CLIP	23824327
MIRT630480	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT630479	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT630478	hsa-miR-6847-3p	HITS-CLIP	23824327
MIRT630477	hsa-miR-564	HITS-CLIP	23824327
MIRT630476	hsa-miR-4284	HITS-CLIP	23824327
MIRT630475	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT630474	hsa-miR-6514-3p	HITS-CLIP	23824327

Gene ontology (GO) Show/Hide all (17)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000049	Function	TRNA binding	IEA
GO:0002161	Function	Aminoacyl-tRNA deacylase activity	IEA
GO:0003723	Function	RNA binding	IEA
GO:0005515	Function	Protein binding	IPI	22939629
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	NAS	29410408
GO:0006399	Process	TRNA metabolic process	IBA
GO:0016787	Function	Hydrolase activity	IEA
GO:0051499	Function	D-aminoacyl-tRNA deacylase activity	IEA
GO:0051500	Function	D-tyrosyl-tRNA(Tyr) deacylase activity	IBA
GO:0051500	Function	D-tyrosyl-tRNA(Tyr) deacylase activity	IEA
GO:0106026	Function	Gly-tRNA(Ala) deacylase activity	IEA
GO:0106074	Process	Aminoacyl-tRNA metabolism involved in translational fidelity	IDA	29410408
GO:0106074	Process	Aminoacyl-tRNA metabolism involved in translational fidelity	IEA
GO:0106105	Function	Ala-tRNA(Thr) deacylase activity	IDA	29410408
GO:0106105	Function	Ala-tRNA(Thr) deacylase activity	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q96FN9
• Protein name: D-aminoacyl-tRNA deacylase 2 (EC 3.1.1.96) (Animalia-specific tRNA deacylase) (ATD) (D-tyrosyl-tRNA(Tyr) deacylase 2) (L-alanyl-tRNA deacylase)
• Protein function: Deacylates mischarged D-aminoacyl-tRNAs (By similarity). Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS (By similarity). Probably acts by rejecting L-amino acids from its binding site rather th
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF02580	Tyr_Deacylase	11 → 167	D-Tyr-tRNA(Tyr) deacylase	Family

• Sequence:

  MAEGSRIPQARALLQQCLHARLQIRPADGDVAAQWVEVQRGLVIYVCFFKGADKELLPKM
  VNTLLNVKLSETENGKHVSILDLPGNILIIPQATLGGRLKGRNMQYHSNSGKEEGFELYS
  QFVTLCEKEVAANSKCAEARVVVEHGTYGNRQVLKLDTNGPFTHLIEF

• Sequence length: 168

Related Genes

No strongly related genes found yet for DTD2.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to DTD2.