DRC5 (dynein regulatory complex subunit 5)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 202500 |
| Gene name | Dynein regulatory complex subunit 5 |
| Gene symbol | DRC5 |
| Synonyms (NCBI Gene) |
D6S46FAP155TCTE1
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| Chromosome | 6 |
| Chromosome location | 6p21.1 |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q5JU00 | |||||||||||||||||||||||||
| Protein name | Dynein regulatory complex subunit 5 (T-complex-associated testis-expressed protein 1) (Tcte-1) | |||||||||||||||||||||||||
| Protein function | Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. May play a role in the | |||||||||||||||||||||||||
| PDB | 8J07 | |||||||||||||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 501 | |||||||||||||||||||||||||
| Interactions | View interactions | |||||||||||||||||||||||||
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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Related Genes
Genes most often co-reported with DRC5 across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to DRC5 (see Related Genes above), that are NOT already directly curated for DRC5 itself -- a lead worth checking, not a confirmed association.
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