DNTTIP2 (deoxynucleotidyltransferase terminal interacting protein 2)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 30836
• Gene name: Deoxynucleotidyltransferase terminal interacting protein 2
• Gene symbol: DNTTIP2
• Synonyms (NCBI Gene): ERBP, FCF2, HSU15552, LPTS-RP2, TdIF2
• Chromosome: 1
• Chromosome location: 1p22.1
• Summary: This gene is thought to be involved in chromatin remodeling and gene transcription. The encoded nuclear protein binds to and enhances the transcriptional activity of the estrogen receptor alpha, and also interacts with terminal deoxynucleotidyltransferase

miRNA Show/Hide all (255)

miRTarBase ID	miRNA	Experiments	Reference
MIRT031419	hsa-miR-16-5p	Proteomics	18668040
MIRT048180	hsa-miR-196a-5p	CLASH	23622248
MIRT643535	hsa-miR-5680	HITS-CLIP	23824327
MIRT643534	hsa-miR-5579-5p	HITS-CLIP	23824327
MIRT643533	hsa-miR-203a-3p	HITS-CLIP	23824327
MIRT643532	hsa-miR-584-5p	HITS-CLIP	23824327
MIRT643531	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT615299	hsa-miR-548e-5p	HITS-CLIP	23824327
MIRT615297	hsa-miR-4422	HITS-CLIP	23824327
MIRT615298	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT615296	hsa-miR-432-5p	HITS-CLIP	23824327
MIRT615294	hsa-miR-6874-5p	HITS-CLIP	23824327
MIRT615295	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT539864	hsa-miR-548a-3p	HITS-CLIP	23824327
MIRT539863	hsa-miR-548ar-3p	HITS-CLIP	23824327
MIRT539862	hsa-miR-548az-3p	HITS-CLIP	23824327
MIRT539861	hsa-miR-548e-3p	HITS-CLIP	23824327
MIRT539860	hsa-miR-548f-3p	HITS-CLIP	23824327
MIRT539859	hsa-miR-5582-3p	HITS-CLIP	23824327
MIRT539858	hsa-miR-8485	HITS-CLIP	23824327
MIRT539857	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539856	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539855	hsa-miR-603	HITS-CLIP	23824327
MIRT629335	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT539854	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT539853	hsa-miR-3941	HITS-CLIP	23824327
MIRT629334	hsa-miR-4672	HITS-CLIP	23824327
MIRT615299	hsa-miR-548e-5p	HITS-CLIP	23824327
MIRT615297	hsa-miR-4422	HITS-CLIP	23824327
MIRT615298	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT526778	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT526777	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT526776	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT615296	hsa-miR-432-5p	HITS-CLIP	23824327
MIRT625336	hsa-miR-505-5p	HITS-CLIP	23824327
MIRT615294	hsa-miR-6874-5p	HITS-CLIP	23824327
MIRT615295	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT615299	hsa-miR-548e-5p	HITS-CLIP	23824327
MIRT615297	hsa-miR-4422	HITS-CLIP	23824327
MIRT615298	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT615296	hsa-miR-432-5p	HITS-CLIP	23824327
MIRT615294	hsa-miR-6874-5p	HITS-CLIP	23824327
MIRT615295	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT498830	hsa-miR-4302	PAR-CLIP	20371350
MIRT498829	hsa-miR-4289	PAR-CLIP	20371350
MIRT498828	hsa-miR-145-3p	PAR-CLIP	20371350
MIRT498827	hsa-miR-7-5p	PAR-CLIP	20371350
MIRT498826	hsa-miR-6077	PAR-CLIP	20371350
MIRT498825	hsa-miR-3190-3p	PAR-CLIP	20371350
MIRT498824	hsa-miR-6833-5p	PAR-CLIP	20371350
MIRT498823	hsa-miR-4752	PAR-CLIP	20371350
MIRT498830	hsa-miR-4302	PAR-CLIP	20371350
MIRT498829	hsa-miR-4289	PAR-CLIP	20371350
MIRT498828	hsa-miR-145-3p	PAR-CLIP	20371350
MIRT498827	hsa-miR-7-5p	PAR-CLIP	20371350
MIRT498826	hsa-miR-6077	PAR-CLIP	20371350
MIRT498825	hsa-miR-3190-3p	PAR-CLIP	20371350
MIRT498824	hsa-miR-6833-5p	PAR-CLIP	20371350
MIRT498823	hsa-miR-4752	PAR-CLIP	20371350
MIRT498830	hsa-miR-4302	PAR-CLIP	21572407
MIRT498829	hsa-miR-4289	PAR-CLIP	21572407
MIRT498828	hsa-miR-145-3p	PAR-CLIP	21572407
MIRT498827	hsa-miR-7-5p	PAR-CLIP	21572407
MIRT498826	hsa-miR-6077	PAR-CLIP	21572407
MIRT498825	hsa-miR-3190-3p	PAR-CLIP	21572407
MIRT498824	hsa-miR-6833-5p	PAR-CLIP	21572407
MIRT498823	hsa-miR-4752	PAR-CLIP	21572407
MIRT539864	hsa-miR-548a-3p	PAR-CLIP	21572407
MIRT539863	hsa-miR-548ar-3p	PAR-CLIP	21572407
MIRT539862	hsa-miR-548az-3p	PAR-CLIP	21572407
MIRT539861	hsa-miR-548e-3p	PAR-CLIP	21572407
MIRT539860	hsa-miR-548f-3p	PAR-CLIP	21572407
MIRT539859	hsa-miR-5582-3p	PAR-CLIP	21572407
MIRT539858	hsa-miR-8485	PAR-CLIP	21572407
MIRT539857	hsa-miR-329-3p	PAR-CLIP	21572407
MIRT539856	hsa-miR-362-3p	PAR-CLIP	21572407
MIRT539855	hsa-miR-603	PAR-CLIP	21572407
MIRT539854	hsa-miR-4789-3p	PAR-CLIP	21572407
MIRT539853	hsa-miR-3941	PAR-CLIP	21572407
MIRT526781	hsa-miR-3617-5p	PAR-CLIP	22012620
MIRT526780	hsa-miR-641	PAR-CLIP	22012620
MIRT526779	hsa-miR-4729	PAR-CLIP	22012620
MIRT526778	hsa-miR-371b-5p	PAR-CLIP	22012620
MIRT526777	hsa-miR-373-5p	PAR-CLIP	22012620
MIRT526776	hsa-miR-616-5p	PAR-CLIP	22012620
MIRT526775	hsa-miR-371a-5p	PAR-CLIP	22012620
MIRT526774	hsa-miR-372-5p	PAR-CLIP	22012620
MIRT526773	hsa-miR-513c-5p	PAR-CLIP	22012620
MIRT526772	hsa-miR-514b-5p	PAR-CLIP	22012620
MIRT526771	hsa-miR-7156-3p	PAR-CLIP	22012620
MIRT526770	hsa-miR-491-3p	PAR-CLIP	22012620
MIRT515003	hsa-miR-3609	PAR-CLIP	23446348
MIRT515002	hsa-miR-548ah-5p	PAR-CLIP	23446348
MIRT515001	hsa-miR-106a-5p	PAR-CLIP	23446348
MIRT515000	hsa-miR-106b-5p	PAR-CLIP	23446348
MIRT514999	hsa-miR-17-5p	PAR-CLIP	23446348
MIRT514998	hsa-miR-20a-5p	PAR-CLIP	23446348
MIRT514997	hsa-miR-20b-5p	PAR-CLIP	23446348
MIRT514996	hsa-miR-519d-3p	PAR-CLIP	23446348
MIRT514995	hsa-miR-526b-3p	PAR-CLIP	23446348
MIRT514994	hsa-miR-93-5p	PAR-CLIP	23446348
MIRT514993	hsa-miR-4796-3p	PAR-CLIP	23446348
MIRT514991	hsa-miR-3121-3p	PAR-CLIP	23446348
MIRT514992	hsa-miR-4803	PAR-CLIP	23446348
MIRT514990	hsa-miR-802	PAR-CLIP	23446348
MIRT514989	hsa-miR-4728-3p	PAR-CLIP	23446348
MIRT514988	hsa-miR-875-3p	PAR-CLIP	23446348
MIRT514987	hsa-miR-3148	PAR-CLIP	23446348
MIRT514986	hsa-miR-6124	PAR-CLIP	23446348
MIRT514985	hsa-miR-5585-3p	PAR-CLIP	23446348
MIRT498830	hsa-miR-4302	PAR-CLIP	23446348
MIRT498829	hsa-miR-4289	PAR-CLIP	23446348
MIRT498828	hsa-miR-145-3p	PAR-CLIP	23446348
MIRT498827	hsa-miR-7-5p	PAR-CLIP	23446348
MIRT498826	hsa-miR-6077	PAR-CLIP	23446348
MIRT498825	hsa-miR-3190-3p	PAR-CLIP	23446348
MIRT498824	hsa-miR-6833-5p	PAR-CLIP	23446348
MIRT498823	hsa-miR-4752	PAR-CLIP	23446348
MIRT498830	hsa-miR-4302	PAR-CLIP	24398324
MIRT498829	hsa-miR-4289	PAR-CLIP	24398324
MIRT498828	hsa-miR-145-3p	PAR-CLIP	24398324
MIRT498827	hsa-miR-7-5p	PAR-CLIP	24398324
MIRT498826	hsa-miR-6077	PAR-CLIP	24398324
MIRT498825	hsa-miR-3190-3p	PAR-CLIP	24398324
MIRT498824	hsa-miR-6833-5p	PAR-CLIP	24398324
MIRT498823	hsa-miR-4752	PAR-CLIP	24398324
MIRT440787	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT440787	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT643535	hsa-miR-5680	HITS-CLIP	23824327
MIRT643534	hsa-miR-5579-5p	HITS-CLIP	23824327
MIRT643533	hsa-miR-203a-3p	HITS-CLIP	23824327
MIRT643532	hsa-miR-584-5p	HITS-CLIP	23824327
MIRT643531	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT615299	hsa-miR-548e-5p	HITS-CLIP	23824327
MIRT615297	hsa-miR-4422	HITS-CLIP	23824327
MIRT615298	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT615296	hsa-miR-432-5p	HITS-CLIP	23824327
MIRT615294	hsa-miR-6874-5p	HITS-CLIP	23824327
MIRT615295	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT539864	hsa-miR-548a-3p	HITS-CLIP	23824327
MIRT539863	hsa-miR-548ar-3p	HITS-CLIP	23824327
MIRT539862	hsa-miR-548az-3p	HITS-CLIP	23824327
MIRT539861	hsa-miR-548e-3p	HITS-CLIP	23824327
MIRT539860	hsa-miR-548f-3p	HITS-CLIP	23824327
MIRT539859	hsa-miR-5582-3p	HITS-CLIP	23824327
MIRT539858	hsa-miR-8485	HITS-CLIP	23824327
MIRT539857	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539856	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539855	hsa-miR-603	HITS-CLIP	23824327
MIRT629335	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT539854	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT539853	hsa-miR-3941	HITS-CLIP	23824327
MIRT629334	hsa-miR-4672	HITS-CLIP	23824327
MIRT615299	hsa-miR-548e-5p	HITS-CLIP	23824327
MIRT615297	hsa-miR-4422	HITS-CLIP	23824327
MIRT615298	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT526778	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT526777	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT526776	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT615296	hsa-miR-432-5p	HITS-CLIP	23824327
MIRT625336	hsa-miR-505-5p	HITS-CLIP	23824327
MIRT615294	hsa-miR-6874-5p	HITS-CLIP	23824327
MIRT615295	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT615299	hsa-miR-548e-5p	HITS-CLIP	23824327
MIRT615297	hsa-miR-4422	HITS-CLIP	23824327
MIRT615298	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT615296	hsa-miR-432-5p	HITS-CLIP	23824327
MIRT615294	hsa-miR-6874-5p	HITS-CLIP	23824327
MIRT615295	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT498830	hsa-miR-4302	PAR-CLIP	20371350
MIRT498829	hsa-miR-4289	PAR-CLIP	20371350
MIRT498828	hsa-miR-145-3p	PAR-CLIP	20371350
MIRT498827	hsa-miR-7-5p	PAR-CLIP	20371350
MIRT498826	hsa-miR-6077	PAR-CLIP	20371350
MIRT498825	hsa-miR-3190-3p	PAR-CLIP	20371350
MIRT498824	hsa-miR-6833-5p	PAR-CLIP	20371350
MIRT498823	hsa-miR-4752	PAR-CLIP	20371350
MIRT498830	hsa-miR-4302	PAR-CLIP	20371350
MIRT498829	hsa-miR-4289	PAR-CLIP	20371350
MIRT498828	hsa-miR-145-3p	PAR-CLIP	20371350
MIRT498827	hsa-miR-7-5p	PAR-CLIP	20371350
MIRT498826	hsa-miR-6077	PAR-CLIP	20371350
MIRT498825	hsa-miR-3190-3p	PAR-CLIP	20371350
MIRT498824	hsa-miR-6833-5p	PAR-CLIP	20371350
MIRT498823	hsa-miR-4752	PAR-CLIP	20371350
MIRT498830	hsa-miR-4302	PAR-CLIP	21572407
MIRT498829	hsa-miR-4289	PAR-CLIP	21572407
MIRT498828	hsa-miR-145-3p	PAR-CLIP	21572407
MIRT498827	hsa-miR-7-5p	PAR-CLIP	21572407
MIRT498826	hsa-miR-6077	PAR-CLIP	21572407
MIRT498825	hsa-miR-3190-3p	PAR-CLIP	21572407
MIRT498824	hsa-miR-6833-5p	PAR-CLIP	21572407
MIRT498823	hsa-miR-4752	PAR-CLIP	21572407
MIRT539864	hsa-miR-548a-3p	PAR-CLIP	21572407
MIRT539863	hsa-miR-548ar-3p	PAR-CLIP	21572407
MIRT539862	hsa-miR-548az-3p	PAR-CLIP	21572407
MIRT539861	hsa-miR-548e-3p	PAR-CLIP	21572407
MIRT539860	hsa-miR-548f-3p	PAR-CLIP	21572407
MIRT539859	hsa-miR-5582-3p	PAR-CLIP	21572407
MIRT539858	hsa-miR-8485	PAR-CLIP	21572407
MIRT539857	hsa-miR-329-3p	PAR-CLIP	21572407
MIRT539856	hsa-miR-362-3p	PAR-CLIP	21572407
MIRT539855	hsa-miR-603	PAR-CLIP	21572407
MIRT539854	hsa-miR-4789-3p	PAR-CLIP	21572407
MIRT539853	hsa-miR-3941	PAR-CLIP	21572407
MIRT526781	hsa-miR-3617-5p	PAR-CLIP	22012620
MIRT526780	hsa-miR-641	PAR-CLIP	22012620
MIRT526779	hsa-miR-4729	PAR-CLIP	22012620
MIRT526778	hsa-miR-371b-5p	PAR-CLIP	22012620
MIRT526777	hsa-miR-373-5p	PAR-CLIP	22012620
MIRT526776	hsa-miR-616-5p	PAR-CLIP	22012620
MIRT526775	hsa-miR-371a-5p	PAR-CLIP	22012620
MIRT526774	hsa-miR-372-5p	PAR-CLIP	22012620
MIRT526773	hsa-miR-513c-5p	PAR-CLIP	22012620
MIRT526772	hsa-miR-514b-5p	PAR-CLIP	22012620
MIRT526771	hsa-miR-7156-3p	PAR-CLIP	22012620
MIRT526770	hsa-miR-491-3p	PAR-CLIP	22012620
MIRT515003	hsa-miR-3609	PAR-CLIP	23446348
MIRT515002	hsa-miR-548ah-5p	PAR-CLIP	23446348
MIRT515001	hsa-miR-106a-5p	PAR-CLIP	23446348
MIRT515000	hsa-miR-106b-5p	PAR-CLIP	23446348
MIRT514999	hsa-miR-17-5p	PAR-CLIP	23446348
MIRT514998	hsa-miR-20a-5p	PAR-CLIP	23446348
MIRT514997	hsa-miR-20b-5p	PAR-CLIP	23446348
MIRT514996	hsa-miR-519d-3p	PAR-CLIP	23446348
MIRT514995	hsa-miR-526b-3p	PAR-CLIP	23446348
MIRT514994	hsa-miR-93-5p	PAR-CLIP	23446348
MIRT514993	hsa-miR-4796-3p	PAR-CLIP	23446348
MIRT514991	hsa-miR-3121-3p	PAR-CLIP	23446348
MIRT514992	hsa-miR-4803	PAR-CLIP	23446348
MIRT514990	hsa-miR-802	PAR-CLIP	23446348
MIRT514989	hsa-miR-4728-3p	PAR-CLIP	23446348
MIRT514988	hsa-miR-875-3p	PAR-CLIP	23446348
MIRT514987	hsa-miR-3148	PAR-CLIP	23446348
MIRT514986	hsa-miR-6124	PAR-CLIP	23446348
MIRT514985	hsa-miR-5585-3p	PAR-CLIP	23446348
MIRT498830	hsa-miR-4302	PAR-CLIP	23446348
MIRT498829	hsa-miR-4289	PAR-CLIP	23446348
MIRT498828	hsa-miR-145-3p	PAR-CLIP	23446348
MIRT498827	hsa-miR-7-5p	PAR-CLIP	23446348
MIRT498826	hsa-miR-6077	PAR-CLIP	23446348
MIRT498825	hsa-miR-3190-3p	PAR-CLIP	23446348
MIRT498824	hsa-miR-6833-5p	PAR-CLIP	23446348
MIRT498823	hsa-miR-4752	PAR-CLIP	23446348
MIRT498830	hsa-miR-4302	PAR-CLIP	24398324
MIRT498829	hsa-miR-4289	PAR-CLIP	24398324
MIRT498828	hsa-miR-145-3p	PAR-CLIP	24398324
MIRT498827	hsa-miR-7-5p	PAR-CLIP	24398324
MIRT498826	hsa-miR-6077	PAR-CLIP	24398324
MIRT498825	hsa-miR-3190-3p	PAR-CLIP	24398324
MIRT498824	hsa-miR-6833-5p	PAR-CLIP	24398324
MIRT498823	hsa-miR-4752	PAR-CLIP	24398324
MIRT2448466	hsa-miR-3662	CLIP-seq
MIRT2448467	hsa-miR-522	CLIP-seq
MIRT2448468	hsa-miR-935	CLIP-seq

Gene ontology (GO) Show/Hide all (11)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005694	Component	Chromosome	IDA
GO:0005730	Component	Nucleolus	IBA
GO:0005730	Component	Nucleolus	IDA
GO:0005730	Component	Nucleolus	IEA
GO:0006396	Process	RNA processing	IBA
GO:0032040	Component	Small-subunit processome	IDA	34516797
GO:0042274	Process	Ribosomal small subunit biogenesis	IDA	34516797

Other IDs

• MIM: 611199
• HGNC: 24013
• e!Ensembl: ENSG00000067334

Protein

• UniProt ID: Q5QJE6
• Protein name: Deoxynucleotidyltransferase terminal-interacting protein 2 (Estrogen receptor-binding protein) (LPTS-interacting protein 2) (LPTS-RP2) (Terminal deoxynucleotidyltransferase-interacting factor 2) (TdIF2) (TdT-interacting factor 2)
• Protein function: Regulates the transcriptional activity of DNTT and ESR1. May function as a chromatin remodeling protein (PubMed:12786946, PubMed:15047147). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. Du
• PDB: 7MQ8 , 7MQ9 , 7MQA
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF08698	Fcf2	637 → 731	Fcf2 pre-rRNA processing	Family

• Tissue specificity: TISSUE SPECIFICITY: Widely expressed with higher levels in testis. {ECO:0000269|PubMed:12786946, ECO:0000269|PubMed:15047147}.
• Sequence:

  MVVTRSARAKASIQAASAESSGQKSFAANGIQAHPESSTGSDARTTAESQTTGKQSLIPR
  TPKARKRKSRTTGSLPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVS
  SVRKKPKVTPTKESYTEEIVSEAESHVSGISRIVLPTEKTTGARRSKAKSLTDPSQESHT
  EAISDAETSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSD
  TRQTSHLQARSLSEINKPNFYNNDFDDDFSHRSSENILTVHEQANVESLKETKQNCKDLD
  EDANGITDEGKEINEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSEAVM
  KSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGNVDF
  ECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSENSENEEDTLCFVENSGQRESLSGDTG
  SLSCDNALFVIDTTPGMSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENED
  EFSDEEDFLNSTKAKLLKLTSSSIDPGLSIKQLGGLYINFNADKLQSNKRTLTQIKEKKK
  NELLQKAVITPDFEKNHCVPPYSESKYQLQKKRRKERQKTAGDGWFGMKAPEMTNELKND
  LKALKMRASMDPKRFYKKNDRDGFPKYFQIGTIVDNPADFYHSRIPKKQRKRTIVEELLA
  DSEFRRYNRRKYSEIMAEKAANAAGKKFRKKKKFRN

• Sequence length: 756

Related Genes

No strongly related genes found yet for DNTTIP2.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to DNTTIP2.