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Gene Gene information from NCBI Gene database.
Entrez ID 22826
Gene name DnaJ heat shock protein family (Hsp40) member C8
Gene symbol DNAJC8
Synonyms (NCBI Gene)
HSPC331SPF31
Chromosome 1
Chromosome location 1p35.3
miRNA miRNA information provided by mirtarbase database.
421 Show/Hide all (421)
miRTarBase ID miRNA Experiments Reference
MIRT019673 hsa-miR-375 Microarray 20215506
MIRT052102 hsa-let-7b-5p CLASH 23622248
MIRT045874 hsa-miR-128-3p CLASH 23622248
MIRT045369 hsa-miR-185-5p CLASH 23622248
MIRT038453 hsa-miR-296-3p CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
9 Show/Hide all (9)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 17332742, 28298427, 35271311
GO:0005634 Component Nucleus IBA
GO:0005634 Component Nucleus IDA 27133716
GO:0005634 Component Nucleus IEA
GO:0005654 Component Nucleoplasm IDA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O75937
Protein name DnaJ homolog subfamily C member 8 (Splicing protein spf31)
Protein function Suppresses polyglutamine (polyQ) aggregation of ATXN3 in neuronal cells (PubMed:27133716).
PDB 7VPX
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00226 DnaJ 57 → 121 DnaJ domain Domain
Tissue specificity TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:27133716}.
Sequence
MAASGESGTSGGGGSTEEAFMTFYSEVKQIEKRDSVLTSKNQIERLTRPGSSYFNLNPFE
VLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRAL
D
VIQAGKEYVEHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRKER
EAKEMHERKRQREEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGKKEKKNRT
FLRPPKVKMEQRE
Sequence length 253
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Reactome Pathway
mRNA Splicing - Major Pathway