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Gene Gene information from NCBI Gene database.
Entrez ID 85406
Gene name DnaJ heat shock protein family (Hsp40) member C14
Gene symbol DNAJC14
Synonyms (NCBI Gene)
DNAJDRIP78HDJ3LIP6
Chromosome 12
Chromosome location 12q13.2
miRNA miRNA information provided by mirtarbase database.
315 Show/Hide all (315)
miRTarBase ID miRNA Experiments Reference
MIRT044561 hsa-miR-320a CLASH 23622248
MIRT043994 hsa-miR-378a-5p CLASH 23622248
MIRT940637 hsa-miR-1207-3p CLIP-seq
MIRT940638 hsa-miR-1228 CLIP-seq
MIRT940639 hsa-miR-1273e CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
9 Show/Hide all (9)
GO ID Ontology Definition Evidence Reference
GO:0001664 Function G protein-coupled receptor binding IEA
GO:0005515 Function Protein binding IPI 28514442, 33961781
GO:0005783 Component Endoplasmic reticulum IEA
GO:0005789 Component Endoplasmic reticulum membrane IEA
GO:0015031 Process Protein transport IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
606092 24581 ENSG00000135392
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q6Y2X3
Protein name DnaJ homolog subfamily C member 14 (DnaJ protein homolog 3) (Dopamine receptor-interacting protein of 78 kDa) (DRIP78) (Human DnaJ protein 3) (hDj-3)
Protein function Regulates the export of target proteins, such as DRD1, from the endoplasmic reticulum to the cell surface.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00226 DnaJ 443 → 504 DnaJ domain Domain
PF14901 Jiv90 531 → 620 Cleavage inducing molecular chaperone Domain
Tissue specificity TISSUE SPECIFICITY: Highly expressed in pancreas and selectively expressed in brain, lung, liver, skeletal muscle and kidney. {ECO:0000269|PubMed:12768437}.
Sequence
MAQKHPGERGLYGAHHSGGASLRTLGPSVDPEIPSFSGLRDSAGTAPNGTRCLTEHSGPK
HTQHPNPAHWLDPSHGPPGGPGPPRDAEDPDQSETSSEEESGVDQELSKENETGNQKDGN
SFLSIPSACNCQGTPGIPEGPYSEGGNGSSSNFCHHCTSPALGEDELEEEYDDEESLKFP
SDFSRVSSGKKPPSRRQRHRFPTKEDTREGGRRDPRSPGRHRLGRKRSQADKRKGLGLWG
AEELCQLGQAGFWWLIELLVLVGEYVETCGHLIYACRQLKSSDLDLFRVWMGVWTGRLGG
WAQVMFQFLSQGFYCGVGLFTRFLKLLGALLLLALALFLGFLQLGWRFLVGLGDRLGWRD
KATWLFSWLDSPALQRCLTLLRDSRPWQRLVRIVQWGWLELPWVKQNINRQGNAPVASGR
YCQPEEEVARLLTMAGVPEDELNPFHVLGVEATASDVELKKAYRQLAVMVHPDKNHHPRA
EEAFKVLRAAWDIVSNAEKRKEYE
MKRMAENELSRSVNEFLSKLQDDLKEAMNTMMCSRC
QGKHRRFEMDREPKSARYCAECNRLHPAEEGDFWAESSMLGLKITYFALMDGKVYDITEW
AGCQRVGISPDTHRVPYHIS
FGSRIPGTRGRQRATPDAPPADLQDFLSRIFQVPPGQMPN
GNFFAAPQPAPGAAAASKPNSTVPKGEAKPKRRKKVRRPFQR
Sequence length 702
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Reference Evidence Score
EBV-positive nodal T- and NK-cell lymphoma Likely benign ClinVar —
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Show/Hide Text Mining Associations (13)
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Asthma Asthma Pubtator 37649101 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Fibrolamellar Hepatocellular Carcinoma Hepatocellular Carcinoma BEFREE 31063128
★★★★★
★☆☆☆☆
Found in Text Mining only
Huntington Disease Huntington Disease BEFREE 22396390
★★★★★
★☆☆☆☆
Found in Text Mining only
Malignant neoplasm of stomach Stomach Neoplasms BEFREE 28481734
★★★★★
★☆☆☆☆
Found in Text Mining only
Neoplasms Neoplasms BEFREE 15601829, 21106534, 24578576, 28481734
★★★★★
★☆☆☆☆
Found in Text Mining only
Neurodegenerative Diseases Neurodegenerative disorder Pubtator 27261198 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Neurodegenerative Disorders Neurodegenerative Disorders BEFREE 29203718
★★★★★
★☆☆☆☆
Found in Text Mining only
Parkinson Disease Parkinson disease BEFREE 16344956
★★★★★
★☆☆☆☆
Found in Text Mining only
Parkinson Disease Parkinson disease Pubtator 16344956, 25118025 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Parkinsonian Disorders Parkinson Disease BEFREE 31082451
★★★★★
★☆☆☆☆
Found in Text Mining only