DNAJB12 (DnaJ heat shock protein family (Hsp40) member B12)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 54788 |
| Gene name | DnaJ heat shock protein family (Hsp40) member B12 |
| Gene symbol | DNAJB12 |
| Synonyms (NCBI Gene) |
DJ10
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| Chromosome | 10 |
| Chromosome location | 10q22.1 |
| Summary | DNAJB12 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the |
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miRNA
miRNA information provided by mirtarbase database.
519
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9NXW2 | |||||||||||||||
| Protein name | DnaJ homolog subfamily B member 12 | |||||||||||||||
| Protein function | Acts as a co-chaperone with HSPA8/Hsc70; required to promote protein folding and trafficking, prevent aggregation of client proteins, and promote unfolded proteins to endoplasmic reticulum-associated degradation (ERAD) pathway (PubMed:21148293, | |||||||||||||||
| PDB | 2CTP | |||||||||||||||
| Family and domains |
Pfam
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| Sequence |
MESNKDEAERCISIALKAIQSNQPDRALRFLEKAQRLYPTPRVRALIESLNQKPQTAGDQ |
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| Sequence length | 375 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Related Genes
Genes most often co-reported with DNAJB12 across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to DNAJB12 (see Related Genes above), that are NOT already directly curated for DNAJB12 itself -- a lead worth checking, not a confirmed association.
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