DENND11 (DENN domain containing 11)

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Gene Gene information from NCBI Gene database.
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Entrez ID 57189
Gene name DENN domain containing 11
Gene symbol DENND11
Synonyms (NCBI Gene)
KIAA1147LCHNPRO2561
Chromosome 7
Chromosome location 7q34
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
2
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GO ID Ontology Definition Evidence Reference
GO:0005085 Function Guanyl-nucleotide exchange factor activity IEA
GO:0005737 Component Cytoplasm IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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MIM HGNC e!Ensembl
620122 29472 ENSG00000257093
Protein Protein information from UniProt database.
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UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
A4D1U4
Protein name DENN domain-containing protein 11 (DENND11) (Protein LCHN)
Protein function Probable guanine nucleotide exchange factor (GEF). May promote the exchange of GDP to GTP, converting inactive GDP-bound small GTPases into their active GTP-bound form (Probable). May play a role in neuritogenesis, as well as in neuronal recover
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF09804 DENND11 80 → 347 DENN domain-containing protein 11 Family
Sequence 
MVEQGDAAPLLRWAEGPAVSLPQAPQPQAGGWGRGGGGGARPAAEPPRRREPEEPAAPEV
LLQPGRLELGDVEEDQVVAVFVVTFDPRSGNMVEWCLPQDIDLEGVEFKSMASGSHKIQS
DFIYFRKGPFFGLACFANMPVESELERGARMKSVGILSPSYTLLYRYMHFLENQVRHQLE
MPGHYSHLAAFYEDKKGVLHAGPGRGSSLPPVYWLPSIHRYMYPEMKITHPAGCMSQFIK
FFGEQILILWKFALLRKRILIFSPPPVGVVCYRVYCCCCLANVSLPGIGGTIPESKPFFY
VNVADIESLEVEVSYVACTTEKIFEEKRELYDVYVDNQNVKTHHDHLQPLLKINSADREK
YRRLNEQRQMLLYSQEVEEDYNPCEEDLFVLFFLEQNNRIFQTLLEVSASQDKTLTAEHA
RGMGLDPQGDRSFLLDLLEAYGIDVMLVIDNPCCP
Sequence length 455
Interactions View interactions

No strongly related genes found yet for DENND11.

No additional diseases found yet through genes similar to DENND11.