DCAF15 (DDB1 and CUL4 associated factor 15)

Download as csv Download as pdf

Log in to bookmark this gene

Bookmark This Gene

Title Project / Tag (optional) Note (optional)

Cancel Save

On this page

Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 90379
• Gene name: DDB1 and CUL4 associated factor 15
• Gene symbol: DCAF15
• Synonyms (NCBI Gene): C19orf72
• Chromosome: 19
• Chromosome location: 19p13.12

miRNA Show/Hide all (210)

miRTarBase ID	miRNA	Experiments	Reference
MIRT461631	hsa-miR-6504-3p	HITS-CLIP	23313552
MIRT461630	hsa-miR-8060	HITS-CLIP	23313552
MIRT696323	hsa-miR-4729	HITS-CLIP	23313552
MIRT461629	hsa-miR-3185	HITS-CLIP	23313552
MIRT696322	hsa-miR-655-5p	HITS-CLIP	23313552
MIRT696321	hsa-miR-377-5p	HITS-CLIP	23313552
MIRT696320	hsa-miR-6086	HITS-CLIP	23313552
MIRT461627	hsa-miR-4666a-5p	HITS-CLIP	23313552
MIRT461626	hsa-miR-556-3p	HITS-CLIP	23313552
MIRT461632	hsa-miR-191-5p	PAR-CLIP	23592263
MIRT461631	hsa-miR-6504-3p	PAR-CLIP	23592263
MIRT461630	hsa-miR-8060	PAR-CLIP	23592263
MIRT461629	hsa-miR-3185	PAR-CLIP	23592263
MIRT461628	hsa-miR-4450	PAR-CLIP	23592263
MIRT461627	hsa-miR-4666a-5p	PAR-CLIP	23592263
MIRT461626	hsa-miR-556-3p	PAR-CLIP	23592263
MIRT461625	hsa-miR-4435	PAR-CLIP	23592263
MIRT461624	hsa-miR-6857-5p	PAR-CLIP	23592263
MIRT461631	hsa-miR-6504-3p	HITS-CLIP	23313552
MIRT461630	hsa-miR-8060	HITS-CLIP	23313552
MIRT696323	hsa-miR-4729	HITS-CLIP	23313552
MIRT461629	hsa-miR-3185	HITS-CLIP	23313552
MIRT696322	hsa-miR-655-5p	HITS-CLIP	23313552
MIRT696321	hsa-miR-377-5p	HITS-CLIP	23313552
MIRT696320	hsa-miR-6086	HITS-CLIP	23313552
MIRT461627	hsa-miR-4666a-5p	HITS-CLIP	23313552
MIRT461626	hsa-miR-556-3p	HITS-CLIP	23313552
MIRT461632	hsa-miR-191-5p	PAR-CLIP	23592263
MIRT461631	hsa-miR-6504-3p	PAR-CLIP	23592263
MIRT461630	hsa-miR-8060	PAR-CLIP	23592263
MIRT461629	hsa-miR-3185	PAR-CLIP	23592263
MIRT461628	hsa-miR-4450	PAR-CLIP	23592263
MIRT461627	hsa-miR-4666a-5p	PAR-CLIP	23592263
MIRT461626	hsa-miR-556-3p	PAR-CLIP	23592263
MIRT461625	hsa-miR-4435	PAR-CLIP	23592263
MIRT461624	hsa-miR-6857-5p	PAR-CLIP	23592263
MIRT924666	hsa-let-7a	CLIP-seq
MIRT924667	hsa-let-7b	CLIP-seq
MIRT924668	hsa-let-7c	CLIP-seq
MIRT924669	hsa-let-7d	CLIP-seq
MIRT924670	hsa-let-7e	CLIP-seq
MIRT924671	hsa-let-7f	CLIP-seq
MIRT924672	hsa-let-7g	CLIP-seq
MIRT924673	hsa-let-7i	CLIP-seq
MIRT924674	hsa-miR-1207-5p	CLIP-seq
MIRT924675	hsa-miR-1289	CLIP-seq
MIRT924676	hsa-miR-138	CLIP-seq
MIRT924677	hsa-miR-141	CLIP-seq
MIRT924678	hsa-miR-1908	CLIP-seq
MIRT924679	hsa-miR-1909	CLIP-seq
MIRT924680	hsa-miR-1915	CLIP-seq
MIRT924681	hsa-miR-196a	CLIP-seq
MIRT924682	hsa-miR-196b	CLIP-seq
MIRT924683	hsa-miR-1972	CLIP-seq
MIRT924684	hsa-miR-200a	CLIP-seq
MIRT924685	hsa-miR-3151	CLIP-seq
MIRT924686	hsa-miR-3155	CLIP-seq
MIRT924687	hsa-miR-3155b	CLIP-seq
MIRT924688	hsa-miR-3179	CLIP-seq
MIRT924689	hsa-miR-3180	CLIP-seq
MIRT924690	hsa-miR-3180-3p	CLIP-seq
MIRT924691	hsa-miR-3196	CLIP-seq
MIRT924692	hsa-miR-3198	CLIP-seq
MIRT924693	hsa-miR-3202	CLIP-seq
MIRT924694	hsa-miR-371-3p	CLIP-seq
MIRT924695	hsa-miR-371b-3p	CLIP-seq
MIRT924696	hsa-miR-4259	CLIP-seq
MIRT924697	hsa-miR-4267	CLIP-seq
MIRT924698	hsa-miR-4294	CLIP-seq
MIRT924699	hsa-miR-4302	CLIP-seq
MIRT924700	hsa-miR-4309	CLIP-seq
MIRT924701	hsa-miR-4456	CLIP-seq
MIRT924702	hsa-miR-4458	CLIP-seq
MIRT924703	hsa-miR-4476	CLIP-seq
MIRT924704	hsa-miR-4488	CLIP-seq
MIRT924705	hsa-miR-4493	CLIP-seq
MIRT924706	hsa-miR-4500	CLIP-seq
MIRT924707	hsa-miR-4669	CLIP-seq
MIRT924708	hsa-miR-4697-3p	CLIP-seq
MIRT924709	hsa-miR-4697-5p	CLIP-seq
MIRT924710	hsa-miR-4703-3p	CLIP-seq
MIRT924711	hsa-miR-4704-5p	CLIP-seq
MIRT924712	hsa-miR-4715-5p	CLIP-seq
MIRT924713	hsa-miR-4717-5p	CLIP-seq
MIRT924714	hsa-miR-4726-3p	CLIP-seq
MIRT924715	hsa-miR-4746-5p	CLIP-seq
MIRT924716	hsa-miR-4763-3p	CLIP-seq
MIRT924717	hsa-miR-484	CLIP-seq
MIRT924718	hsa-miR-486-3p	CLIP-seq
MIRT924719	hsa-miR-510	CLIP-seq
MIRT924720	hsa-miR-515-3p	CLIP-seq
MIRT924721	hsa-miR-519e	CLIP-seq
MIRT924722	hsa-miR-541	CLIP-seq
MIRT924723	hsa-miR-654-5p	CLIP-seq
MIRT924724	hsa-miR-663	CLIP-seq
MIRT924725	hsa-miR-744	CLIP-seq
MIRT924726	hsa-miR-98	CLIP-seq
MIRT924683	hsa-miR-1972	CLIP-seq
MIRT1973940	hsa-miR-3616-3p	CLIP-seq
MIRT924722	hsa-miR-541	CLIP-seq
MIRT924723	hsa-miR-654-5p	CLIP-seq
MIRT924666	hsa-let-7a	CLIP-seq
MIRT924667	hsa-let-7b	CLIP-seq
MIRT924668	hsa-let-7c	CLIP-seq
MIRT924669	hsa-let-7d	CLIP-seq
MIRT924670	hsa-let-7e	CLIP-seq
MIRT924671	hsa-let-7f	CLIP-seq
MIRT924672	hsa-let-7g	CLIP-seq
MIRT924673	hsa-let-7i	CLIP-seq
MIRT924674	hsa-miR-1207-5p	CLIP-seq
MIRT2209523	hsa-miR-1234	CLIP-seq
MIRT924675	hsa-miR-1289	CLIP-seq
MIRT2209524	hsa-miR-1293	CLIP-seq
MIRT924676	hsa-miR-138	CLIP-seq
MIRT924677	hsa-miR-141	CLIP-seq
MIRT2209525	hsa-miR-146b-3p	CLIP-seq
MIRT924678	hsa-miR-1908	CLIP-seq
MIRT924679	hsa-miR-1909	CLIP-seq
MIRT2209526	hsa-miR-191	CLIP-seq
MIRT924680	hsa-miR-1915	CLIP-seq
MIRT924681	hsa-miR-196a	CLIP-seq
MIRT924682	hsa-miR-196b	CLIP-seq
MIRT924683	hsa-miR-1972	CLIP-seq
MIRT924684	hsa-miR-200a	CLIP-seq
MIRT2209527	hsa-miR-3150a-3p	CLIP-seq
MIRT924685	hsa-miR-3151	CLIP-seq
MIRT924686	hsa-miR-3155	CLIP-seq
MIRT924687	hsa-miR-3155b	CLIP-seq
MIRT2209528	hsa-miR-3173-5p	CLIP-seq
MIRT2209529	hsa-miR-3175	CLIP-seq
MIRT924688	hsa-miR-3179	CLIP-seq
MIRT924692	hsa-miR-3198	CLIP-seq
MIRT924693	hsa-miR-3202	CLIP-seq
MIRT924694	hsa-miR-371-3p	CLIP-seq
MIRT924695	hsa-miR-371b-3p	CLIP-seq
MIRT924696	hsa-miR-4259	CLIP-seq
MIRT924697	hsa-miR-4267	CLIP-seq
MIRT924698	hsa-miR-4294	CLIP-seq
MIRT924699	hsa-miR-4302	CLIP-seq
MIRT924700	hsa-miR-4309	CLIP-seq
MIRT924701	hsa-miR-4456	CLIP-seq
MIRT924702	hsa-miR-4458	CLIP-seq
MIRT924703	hsa-miR-4476	CLIP-seq
MIRT2209530	hsa-miR-4483	CLIP-seq
MIRT924704	hsa-miR-4488	CLIP-seq
MIRT924705	hsa-miR-4493	CLIP-seq
MIRT924706	hsa-miR-4500	CLIP-seq
MIRT2209531	hsa-miR-4505	CLIP-seq
MIRT2209532	hsa-miR-4666-5p	CLIP-seq
MIRT924708	hsa-miR-4697-3p	CLIP-seq
MIRT924709	hsa-miR-4697-5p	CLIP-seq
MIRT924710	hsa-miR-4703-3p	CLIP-seq
MIRT924711	hsa-miR-4704-5p	CLIP-seq
MIRT924712	hsa-miR-4715-5p	CLIP-seq
MIRT924713	hsa-miR-4717-5p	CLIP-seq
MIRT924714	hsa-miR-4726-3p	CLIP-seq
MIRT2209533	hsa-miR-4731-5p	CLIP-seq
MIRT924715	hsa-miR-4746-5p	CLIP-seq
MIRT924716	hsa-miR-4763-3p	CLIP-seq
MIRT924717	hsa-miR-484	CLIP-seq
MIRT2209534	hsa-miR-485-5p	CLIP-seq
MIRT924718	hsa-miR-486-3p	CLIP-seq
MIRT2209535	hsa-miR-491-5p	CLIP-seq
MIRT924719	hsa-miR-510	CLIP-seq
MIRT924720	hsa-miR-515-3p	CLIP-seq
MIRT924721	hsa-miR-519e	CLIP-seq
MIRT924722	hsa-miR-541	CLIP-seq
MIRT2209536	hsa-miR-637	CLIP-seq
MIRT924723	hsa-miR-654-5p	CLIP-seq
MIRT2209537	hsa-miR-661	CLIP-seq
MIRT924724	hsa-miR-663	CLIP-seq
MIRT924725	hsa-miR-744	CLIP-seq
MIRT2209538	hsa-miR-874	CLIP-seq
MIRT2209539	hsa-miR-939	CLIP-seq
MIRT924726	hsa-miR-98	CLIP-seq
MIRT924666	hsa-let-7a	CLIP-seq
MIRT924667	hsa-let-7b	CLIP-seq
MIRT924668	hsa-let-7c	CLIP-seq
MIRT924669	hsa-let-7d	CLIP-seq
MIRT924670	hsa-let-7e	CLIP-seq
MIRT924671	hsa-let-7f	CLIP-seq
MIRT924672	hsa-let-7g	CLIP-seq
MIRT924673	hsa-let-7i	CLIP-seq
MIRT2386756	hsa-miR-105	CLIP-seq
MIRT924675	hsa-miR-1289	CLIP-seq
MIRT924680	hsa-miR-1915	CLIP-seq
MIRT924681	hsa-miR-196a	CLIP-seq
MIRT924682	hsa-miR-196b	CLIP-seq
MIRT924683	hsa-miR-1972	CLIP-seq
MIRT2386757	hsa-miR-3137	CLIP-seq
MIRT924688	hsa-miR-3179	CLIP-seq
MIRT924692	hsa-miR-3198	CLIP-seq
MIRT924693	hsa-miR-3202	CLIP-seq
MIRT924696	hsa-miR-4259	CLIP-seq
MIRT924698	hsa-miR-4294	CLIP-seq
MIRT924699	hsa-miR-4302	CLIP-seq
MIRT924700	hsa-miR-4309	CLIP-seq
MIRT924702	hsa-miR-4458	CLIP-seq
MIRT924703	hsa-miR-4476	CLIP-seq
MIRT924706	hsa-miR-4500	CLIP-seq
MIRT2386758	hsa-miR-4640-5p	CLIP-seq
MIRT924707	hsa-miR-4669	CLIP-seq
MIRT924708	hsa-miR-4697-3p	CLIP-seq
MIRT924710	hsa-miR-4703-3p	CLIP-seq
MIRT924712	hsa-miR-4715-5p	CLIP-seq
MIRT924713	hsa-miR-4717-5p	CLIP-seq
MIRT924714	hsa-miR-4726-3p	CLIP-seq
MIRT2386759	hsa-miR-4726-5p	CLIP-seq
MIRT924715	hsa-miR-4746-5p	CLIP-seq
MIRT924726	hsa-miR-98	CLIP-seq

Gene ontology (GO) Show/Hide all (10)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000209	Process	Protein polyubiquitination	IDA	28302793, 28437394, 31452512, 31686031
GO:0002376	Process	Immune system process	IEA
GO:0005515	Function	Protein binding	IPI	16949367, 28437394, 32296183
GO:0016567	Process	Protein ubiquitination	IBA
GO:0016567	Process	Protein ubiquitination	IEA
GO:0032814	Process	Regulation of natural killer cell activation	IMP	31452512
GO:0036094	Function	Small molecule binding	IPI	28302793, 28437394, 31686031
GO:0046872	Function	Metal ion binding	IEA
GO:0080008	Component	Cul4-RING E3 ubiquitin ligase complex	IBA
GO:0080008	Component	Cul4-RING E3 ubiquitin ligase complex	IDA	16949367, 28302793, 28437394, 31452512, 31686031

Other IDs

• MIM: 620109
• HGNC: 25095
• e!Ensembl: ENSG00000132017

Protein

• UniProt ID: Q66K64
• Protein name: DDB1- and CUL4-associated factor 15
• Protein function: Substrate-recognition component of the DCX(DCAF15) complex, a cullin-4-RING E3 ubiquitin-protein ligase complex that mediates ubiquitination and degradation of target proteins (PubMed:16949367, PubMed:31452512). The DCX(DCAF15) complex acts as a
• PDB: 6PAI , 6Q0R , 6Q0V , 6Q0W , 6SJ7 , 6UD7 , 6UE5 , 8ROX , 8ROY
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF14939	DCAF15_WD40	48 → 259	DDB1-and CUL4-substrate receptor 15, WD repeat	Repeat

• Sequence:

  MAPSSKSERNSGAGSGGGGPGGAGGKRAAGRRREHVLKQLERVKISGQLSPRLFRKLPPR
  VCVSLKNIVDEDFLYAGHIFLGFSKCGRYVLSYTSSSGDDDFSFYIYHLYWWEFNVHSKL
  KLVRQVRLFQDEEIYSDLYLTVCEWPSDASKVIVFGFNTRSANGMLMNMMMMSDENHRDI
  YVSTVAVPPPGRCAACQDASRAHPGDPNAQCLRHGFMLHTKYQVVYPFPTFQPAFQLKKD
  QVVLLNTSYSLVACAVSVHSAGDRSFCQILYDHSTCPLAPASPPEPQSPELPPALPSFCP
  EAAPARSSGSPEPSPAIAKAKEFVADIFRRAKEAKGGVPEEARPALCPGPSGSRCRAHSE
  PLALCGETAPRDSPPASEAPASEPGYVNYTKLYYVLESGEGTEPEDELEDDKISLPFVVT
  DLRGRNLRPMRERTAVQGQYLTVEQLTLDFEYVINEVIRHDATWGHQFCSFSDYDIVILE
  VCPETNQVLINIGLLLLAFPSPTEEGQLRPKTYHTSLKVAWDLNTGIFETVSVGDLTEVK
  GQTSGSVWSSYRKSCVDMVMKWLVPESSGRYVNRMTNEALHKGCSLKVLADSERYTWIVL
  

• Sequence length: 600

Related Genes

No strongly related genes found yet for DCAF15.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to DCAF15.