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Gene Gene information from NCBI Gene database.
Entrez ID 9802
Gene name DAZ associated protein 2
Gene symbol DAZAP2
Synonyms (NCBI Gene)
PRTB
Chromosome 12
Chromosome location 12q13.13
Summary This gene encodes a proline-rich protein which interacts with the deleted in azoospermia (DAZ) and the deleted in azoospermia-like gene through the DAZ-like repeats. This protein also interacts with the transforming growth factor-beta signaling molecule S
miRNA miRNA information provided by mirtarbase database.
1522 Show/Hide all (1522)
miRTarBase ID miRNA Experiments Reference
MIRT006201 hsa-miR-302a-3p Luciferase reporter assay 22012620
MIRT006201 hsa-miR-302a-3p Luciferase reporter assay 22012620
MIRT006201 hsa-miR-302a-3p Luciferase reporter assay 22012620
MIRT006201 hsa-miR-302a-3p Luciferase reporter assay 22012620
MIRT006201 hsa-miR-302a-3p Luciferase reporter assay 22012620
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
25 Show/Hide all (25)
GO ID Ontology Definition Evidence Reference
GO:0002039 Function P53 binding IPI 33591310
GO:0003713 Function Transcription coactivator activity ISS
GO:0005515 Function Protein binding IPI 10857750, 15231748, 16169070, 16189514, 16713569, 17984221, 19060904, 20211142, 21516116, 21750715, 21900206, 22070932, 24722188, 25416956, 27107012, 28514442, 31515488, 32296183, 32814053, 33961781
GO:0005634 Component Nucleus IDA 17984221, 19304756, 21274613, 33591310
GO:0005634 Component Nucleus IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
607431 2684 ENSG00000183283
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q15038
Protein name DAZ-associated protein 2 (Deleted in azoospermia-associated protein 2) (Proline-rich transcript in brain protein)
Protein function In unstressed cells, promotes SIAH1-mediated polyubiquitination and degradation of the serine/threonine-protein kinase HIPK2, probably by acting as a loading factor that potentiates complex formation between HIPK2 and ubiquitin ligase SIAH1 (Pub
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF11029 DAZAP2 35 → 168 DAZ associated protein 2 (DAZAP2) Family
Tissue specificity TISSUE SPECIFICITY: Widely expressed. Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes. Down-regulated in multiple myeloma. {ECO:0000269|PubMed:10857750}.
Sequence
Sequence length 168
Interactions View interactions