CWF19L2 (CWF19 like cell cycle control factor 2)

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Gene miRNA Gene ontology Other IDs Protein Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 143884
• Gene name: CWF19 like cell cycle control factor 2
• Gene symbol: CWF19L2
• Synonyms (NCBI Gene): -
• Chromosome: 11
• Chromosome location: 11q22.3

miRNA Show/Hide all (31)

miRTarBase ID	miRNA	Experiments	Reference
MIRT917493	hsa-miR-125a-3p	CLIP-seq
MIRT917494	hsa-miR-188-5p	CLIP-seq
MIRT917495	hsa-miR-3140-3p	CLIP-seq
MIRT917496	hsa-miR-3185	CLIP-seq
MIRT917497	hsa-miR-337-3p	CLIP-seq
MIRT917498	hsa-miR-3665	CLIP-seq
MIRT917499	hsa-miR-4760-5p	CLIP-seq
MIRT917500	hsa-miR-570	CLIP-seq
MIRT2511032	hsa-miR-134	CLIP-seq
MIRT2511033	hsa-miR-1912	CLIP-seq
MIRT2511034	hsa-miR-200b	CLIP-seq
MIRT2511035	hsa-miR-200c	CLIP-seq
MIRT2511036	hsa-miR-2110	CLIP-seq
MIRT2511037	hsa-miR-223	CLIP-seq
MIRT2511038	hsa-miR-2278	CLIP-seq
MIRT2511039	hsa-miR-3118	CLIP-seq
MIRT2511040	hsa-miR-3144-5p	CLIP-seq
MIRT2511041	hsa-miR-3150a-3p	CLIP-seq
MIRT2511042	hsa-miR-3164	CLIP-seq
MIRT2511043	hsa-miR-3191	CLIP-seq
MIRT2511044	hsa-miR-3661	CLIP-seq
MIRT2511045	hsa-miR-374c	CLIP-seq
MIRT2511046	hsa-miR-4260	CLIP-seq
MIRT2511047	hsa-miR-4274	CLIP-seq
MIRT2511048	hsa-miR-429	CLIP-seq
MIRT2511049	hsa-miR-4522	CLIP-seq
MIRT2511050	hsa-miR-4652-5p	CLIP-seq
MIRT2511051	hsa-miR-544b	CLIP-seq
MIRT2511052	hsa-miR-622	CLIP-seq
MIRT2511053	hsa-miR-631	CLIP-seq
MIRT2511054	hsa-miR-655	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000398	Process	MRNA splicing, via spliceosome	IBA
GO:0005515	Function	Protein binding	IPI	25416956, 32296183, 32814053, 33961781
GO:0005654	Component	Nucleoplasm	TAS
GO:0071014	Component	Post-mRNA release spliceosomal complex	IBA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q2TBE0
• Protein name: CWF19-like protein 2
• PDB: 6ID0 , 6ID1 , 8RO2
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF04676	CwfJ_C_2	795 → 889	Protein similar to CwfJ C-terminus 2	Family
  PF04677	CwfJ_C_1	662 → 786	Protein similar to CwfJ C-terminus 1	Family

• Sequence:

  MATSMAAASGRFESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWML
  PDVNERIEQFSQEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWV
  EAVPSQTPDKEKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKI
  EQEKNQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRM
  KEQAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKAQNCQ
  ESRESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRESNPRQNQEFS
  FGNLRAKFLRPSDDEELSFHSKGRKFEPLSSSSALVAQGSLCSGFRKPTKNSEERLTSWS
  RSDGRGDKKHSNQKPSETSTDEHQHVPEDPREKSQDEVLRDDPPKKEHLRDTKSTFAGSP
  ERESIHILSVDEKNKLGAKIIKAEMMGNMELAEQLKVQLEKANKFKETITQIPKKSGVEN
  EDQQEVILVRTDQSGRVWPVNTPGKSLESQGGRRKRQMVSTHEERERVRYFHDDDNLSLN
  DLVKNEKMGTAENQNKLFMRMASKFMGKTDGDYYTLDDMFVSKAAERERLGEEEENQRKK
  AIAEHRSLAAQMEKCLYCFDSSQFPKHLIVAIGVKVYLCLPNVRSLTEGHCLIVPLQHHR
  AATLLDEDIWEEIQMFRKSLVKMFEDKGLDCIFLETNMSMKKQYHMVYECIPLPKEVGDM
  APIYFKKAIMESDEEWSMNKKLIDLSSKDIRKSVPRGLPYFSVDFGLHGGFAHVIEDQHK
  FPHYFGKEIIGGMLDIEPRLWRKGIRESFEDQRKKALQFAQWWKPYDFTKSKNY

• Sequence length: 894

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
CARDIOVASCULAR DISEASE	—	GWAS catalog	30595370	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CORONARY ARTERY DISEASE	—	GWAS catalog	29212778, 35915156, 41022758	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERTENSION	—	GWAS catalog	37947095, 39789286	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LARGE ARTERY STROKE	—	GWAS catalog	24262325	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Coronary Artery Disease	Coronary artery disease	GWASCAT_DG	29212778		★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Related Genes

No strongly related genes found yet for CWF19L2.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to CWF19L2.