CSMD3 (CUB and Sushi multiple domains 3)

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Gene miRNA Gene ontology Other IDs Protein Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 114788
• Gene name: CUB and Sushi multiple domains 3
• Gene symbol: CSMD3
• Synonyms (NCBI Gene): -
• Chromosome: 8
• Chromosome location: 8q23.3

miRNA Show/Hide all (31)

miRTarBase ID	miRNA	Experiments	Reference
MIRT912005	hsa-miR-1	CLIP-seq
MIRT912006	hsa-miR-1183	CLIP-seq
MIRT912007	hsa-miR-1256	CLIP-seq
MIRT912008	hsa-miR-206	CLIP-seq
MIRT912009	hsa-miR-2114	CLIP-seq
MIRT912010	hsa-miR-3121-3p	CLIP-seq
MIRT912011	hsa-miR-3130-5p	CLIP-seq
MIRT912012	hsa-miR-3143	CLIP-seq
MIRT912013	hsa-miR-3613-5p	CLIP-seq
MIRT912014	hsa-miR-3614-3p	CLIP-seq
MIRT912015	hsa-miR-3671	CLIP-seq
MIRT912016	hsa-miR-3673	CLIP-seq
MIRT912017	hsa-miR-3674	CLIP-seq
MIRT912018	hsa-miR-409-3p	CLIP-seq
MIRT912019	hsa-miR-4482	CLIP-seq
MIRT912020	hsa-miR-4693-5p	CLIP-seq
MIRT912021	hsa-miR-4720-5p	CLIP-seq
MIRT912022	hsa-miR-4732-5p	CLIP-seq
MIRT912023	hsa-miR-4760-3p	CLIP-seq
MIRT912024	hsa-miR-4799-3p	CLIP-seq
MIRT912025	hsa-miR-543	CLIP-seq
MIRT912026	hsa-miR-607	CLIP-seq
MIRT912027	hsa-miR-613	CLIP-seq
MIRT912028	hsa-miR-664	CLIP-seq
MIRT1970335	hsa-miR-1208	CLIP-seq
MIRT1970336	hsa-miR-147	CLIP-seq
MIRT1970337	hsa-miR-2052	CLIP-seq
MIRT1970338	hsa-miR-2113	CLIP-seq
MIRT1970339	hsa-miR-452	CLIP-seq
MIRT1970340	hsa-miR-4676-3p	CLIP-seq
MIRT1970341	hsa-miR-599	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	ISS
GO:0016020	Component	Membrane	IEA
GO:0050773	Process	Regulation of dendrite development	IEA
GO:0050773	Process	Regulation of dendrite development	ISS

Other IDs

• MIM: 608399
• HGNC: 19291
• e!Ensembl: ENSG00000164796

Protein

• UniProt ID: Q7Z407
• Protein name: CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3)
• Protein function: Involved in dendrite development.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00084	Sushi	2817 → 2870	Sushi repeat (SCR repeat)	Domain
  PF00084	Sushi	3233 → 3286	Sushi repeat (SCR repeat)	Domain
  PF00084	Sushi	2933 → 2990	Sushi repeat (SCR repeat)	Domain
  PF00084	Sushi	2632 → 2689	Sushi repeat (SCR repeat)	Domain
  PF00084	Sushi	3173 → 3228	Sushi repeat (SCR repeat)	Domain
  PF00084	Sushi	3056 → 3109	Sushi repeat (SCR repeat)	Domain
  PF00084	Sushi	3352 → 3406	Sushi repeat (SCR repeat)	Domain
  PF00084	Sushi	3114 → 3168	Sushi repeat (SCR repeat)	Domain
  PF00084	Sushi	2395 → 2452	Sushi repeat (SCR repeat)	Domain
  PF00084	Sushi	2995 → 3048	Sushi repeat (SCR repeat)	Domain
  PF00084	Sushi	2224 → 2279	Sushi repeat (SCR repeat)	Domain
  PF00084	Sushi	2875 → 2928	Sushi repeat (SCR repeat)	Domain
  PF00084	Sushi	2052 → 2107	Sushi repeat (SCR repeat)	Domain
  PF00084	Sushi	1528 → 1584	Sushi repeat (SCR repeat)	Domain
  PF00084	Sushi	3291 → 3344	Sushi repeat (SCR repeat)	Domain
  PF00084	Sushi	2759 → 2812	Sushi repeat (SCR repeat)	Domain
  PF00084	Sushi	486 → 543	Sushi repeat (SCR repeat)	Domain
  PF00084	Sushi	2694 → 2754	Sushi repeat (SCR repeat)	Domain
  PF00084	Sushi	1010 → 1063	Sushi repeat (SCR repeat)	Domain
  PF00084	Sushi	1182 → 1237	Sushi repeat (SCR repeat)	Domain
  PF00084	Sushi	3411 → 3466	Sushi repeat (SCR repeat)	Domain
  PF00084	Sushi	664 → 717	Sushi repeat (SCR repeat)	Domain
  PF00084	Sushi	2569 → 2627	Sushi repeat (SCR repeat)	Domain
  PF00084	Sushi	1701 → 1758	Sushi repeat (SCR repeat)	Domain
  PF00084	Sushi	178 → 235	Sushi repeat (SCR repeat)	Domain
  PF00084	Sushi	1878 → 1935	Sushi repeat (SCR repeat)	Domain
  PF00084	Sushi	1354 → 1410	Sushi repeat (SCR repeat)	Domain
  PF00084	Sushi	834 → 891	Sushi repeat (SCR repeat)	Domain
  PF00431	CUB	1588 → 1693	CUB domain	Domain
  PF00431	CUB	895 → 1000	CUB domain	Domain
  PF00431	CUB	1939 → 2044	CUB domain	Domain
  PF00431	CUB	721 → 826	CUB domain	Domain
  PF00431	CUB	2111 → 2216	CUB domain	Domain
  PF00431	CUB	1241 → 1346	CUB domain	Domain
  PF00431	CUB	2283 → 2387	CUB domain	Domain
  PF00431	CUB	1414 → 1520	CUB domain	Domain
  PF00431	CUB	241 → 342	CUB domain	Domain
  PF00431	CUB	548 → 656	CUB domain	Domain
  PF00431	CUB	65 → 170	CUB domain	Domain
  PF00431	CUB	2456 → 2564	CUB domain	Domain
  PF00431	CUB	1067 → 1174	CUB domain	Domain
  PF00431	CUB	1762 → 1867	CUB domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Weakly expressed in most tissues, except in brain. Expressed at intermediate level in brain, including cerebellum, substantia nigra, thalamus, spinal cord, hippocampus and fetal brain. Also expressed in testis. {ECO:0000269|PubMed:1157
• Sequence:

  MKGIRKGESRAKESKPWEPGKRRCAKCGRLDFILMKKMGIKSGFTFWNLVFLLTVSCVKG
  FIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLS
  LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN
  PGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDA
  CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGS
  EPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHTTSTGELEEH
  NRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQRVQVTSLRNSGLDPNTSKDGLSPHPA
  DTQSTRRRPRHAEQIERTKELAVVTHRVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIK
  TASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHR
  PVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGY
  DTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIE
  KESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFP
  CLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDG
  DSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIP
  INARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFS
  APSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSP
  LLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGR
  RYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILS
  PGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSD
  LPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGI
  GDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLN
  YENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTL
  SSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYG
  CNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLR
  CMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNI
  VTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYEL
  QGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITV
  NADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRS
  DGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLT
  CIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVV
  FGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITA
  KGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCET
  VPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQ
  VVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGF
  HLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRW
  NYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET
  IHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQ
  LQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCE
  ALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVW
  DGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPP
  VPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANE
  LRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNI
  QSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYI
  ISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTN
  GGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSF
  ILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCG
  ELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIP
  ELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGS
  PIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPA
  NSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGV
  PPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPG
  TPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTT
  ANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPA
  NGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQIS
  NGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQG
  KREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRH
  GSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHA
  NVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRPA
  LGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSFNASTGRVNATLSNSNMELL
  LSGVYKSQEARLMLRIYLIKVPAHASVKKMKEENWAMDGFVSAEPDGATYVFQGFIQGKD
  YGQFGLQRLGLNMSEGSNSSNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKT
  QYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLNTVCTMV

• Sequence length: 3707

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations Show/Hide Unknown Diseases (32)
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
Acute myeloid leukemia	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Adrenocortical carcinoma, hereditary	Likely benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ALZHEIMER DISEASE	—	GWAS catalog	26830138	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ASTHMA	—	GWAS catalog	27611488	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTISTIC DISORDER	—	CTD, Disgenet CTD, Disgenet	18270536	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BRONCHOPULMONARY DYSPLASIA	—	GWAS catalog	23897914	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CARCINOMA, RENAL CELL	—	CTD	22138691, 23797736	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cervical cancer	Likely benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cholangiocarcinoma	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COMPLEX NEURODEVELOPMENTAL DISORDER	—	GenCC	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CSMD3-associated Hirschsprung disease	Uncertain significance	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CSMD3-related disorder	Uncertain significance; Likely benign; Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial meningioma	Uncertain significance; Likely benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Gastric cancer	Uncertain significance	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hepatocellular carcinoma	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hereditary breast ovarian cancer syndrome	Uncertain significance	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INSOMNIA	—	GWAS catalog	30804565, 35835914	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LUNG ADENOCARCINOMA	—	GWAS catalog	40341939	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lung cancer	Likely benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MAJOR DEPRESSIVE DISORDER	—	GWAS catalog	34586374	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Meningioma	-	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NON-SPECIFIC SYNDROMIC INTELLECTUAL DISABILITY	—	Disgenet	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Nonpapillary renal cell carcinoma	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OSTEOARTHRITIS	—	GWAS catalog	36411363	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PERIPHERAL ARTERIAL DISEASE	—	GWAS catalog	26488411	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	GWAS catalog	35396580	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCOLIOSIS	—	GWAS catalog	30019117	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thymoma	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TOURETTE SYNDROME	—	GWAS catalog	30818990	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 1 DIABETES MELLITUS	—	GWAS catalog	39024449	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine carcinosarcoma	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining Show/Hide Text Mining Associations (30)
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Autistic Disorder	Autism	BEFREE	18270536		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Autistic Disorder	Autism	CTD_human_DG	18270536		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Benign adult familial myoclonic epilepsy	Benign Myoclonic Epilepsy	BEFREE	12943675		★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	22510280		★☆☆☆☆ Found in Text Mining only
Chromophobe Renal Cell Carcinoma	Chromophobe Carcinoma	CTD_human_DG	22138691, 23797736		★☆☆☆☆ Found in Text Mining only
Collecting Duct Carcinoma of the Kidney	Renal Carcinoma	CTD_human_DG	22138691, 23797736		★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	24408017		★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	UNIPROT_DG			★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	24408017, 24475022, 35975176	Associate	★☆☆☆☆ Found in Text Mining only
Conventional (Clear Cell) Renal Cell Carcinoma	Renal Carcinoma	CTD_human_DG	22138691, 23797736		★☆☆☆☆ Found in Text Mining only
Gilles de la Tourette syndrome	Tourette Syndrome	GWASCAT_DG	30818990		★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	Pubtator	34015961	Associate	★☆☆☆☆ Found in Text Mining only
Hemangiosarcoma	Hemangiosarcoma	Pubtator	37106027	Associate	★☆☆☆☆ Found in Text Mining only
Hemorrhage	Hemorrhage	Pubtator	36264285	Associate	★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Mental retardation	LHGDN	15523607		★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	33200540	Associate	★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	22510280		★☆☆☆☆ Found in Text Mining only
Narcolepsy	Narcolepsy	GWASDB_DG	19629137		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	27207013		★☆☆☆☆ Found in Text Mining only
Neurofibrosarcoma	Neurofibrosarcoma	Pubtator	33707600	Associate	★☆☆☆☆ Found in Text Mining only
Obesity Morbid	Obesity	Pubtator	31852448	Associate	★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	35735060	Associate	★☆☆☆☆ Found in Text Mining only
Papillary Renal Cell Carcinoma	Papillary Renal Carcinoma	CTD_human_DG	22138691, 23797736		★☆☆☆☆ Found in Text Mining only
Renal Cell Carcinoma	Renal Carcinoma	CTD_human_DG	22138691, 23797736		★☆☆☆☆ Found in Text Mining only
Rheumatoid Arthritis	Rheumatoid arthritis	GWASCAT_DG	30166627		★☆☆☆☆ Found in Text Mining only
Sarcoma	Sarcoma	Pubtator	36153483	Associate	★☆☆☆☆ Found in Text Mining only
Sarcoma Synovial	Synovial sarcoma	Pubtator	26415226	Associate	★☆☆☆☆ Found in Text Mining only
Sarcomatoid Renal Cell Carcinoma	Renal Carcinoma	CTD_human_DG	22138691, 23797736		★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Squamous cell carcinoma	Pubtator	37340028	Associate	★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	32034058	Associate	★☆☆☆☆ Found in Text Mining only

Related Genes

Sort by: Blended Diseases Pathways Evidence source

KCNH3 2 shared diseasesRenal cell carcinoma, Tourette syndrome 2 shared evidence sourcesGenCC (Neurodevelopmental disorder), GWAS catalog (Tourette syndrome) Related via 2 shared diseases including Renal cell carcinoma, Tourette syndrome — evidence mostly GenCC. ZNF536 3 shared diseasesRenal cell carcinoma, Tourette syndrome, Peripheral arterial disease 3 shared evidence sourcesCTD (Renal cell carcinoma), GWAS catalog (Peripheral arterial disease), GWAS catalog (Tourette syndrome) Related via 3 shared diseases including Renal cell carcinoma, Tourette syndrome — evidence mostly GWAS catalog. LMAN2L 2 shared diseasesRenal cell carcinoma, Tourette syndrome 3 shared evidence sourcesCTD (Renal cell carcinoma), GenCC (Neurodevelopmental disorder), GWAS catalog (Tourette syndrome) Related via 2 shared diseases including Renal cell carcinoma, Tourette syndrome — evidence mostly CTD. CCDC7 2 shared diseasesTourette syndrome, Peripheral arterial disease 1 shared evidence sourceGWAS catalog (Peripheral arterial disease) Related via 2 shared diseases including Tourette syndrome, Peripheral arterial disease — evidence mostly GWAS catalog. MAPK10 2 shared diseasesTourette syndrome, Peripheral arterial disease 2 shared evidence sourcesGWAS catalog (Peripheral arterial disease), GWAS catalog (Tourette syndrome) Related via 2 shared diseases including Tourette syndrome, Peripheral arterial disease — evidence mostly GWAS catalog.

Related Gene	Shared Diseases	Shared Disease Names	Shared Pathways	Shared Pathway Names	Shared Evidence Sources	Shared Evidence Names
KCNH3	2	["Renal cell carcinoma","Tourette syndrome"]	0	[]	2	["GenCC (Neurodevelopmental disorder)","GWAS catalog (Tourette syndrome)"]
ZNF536	3	["Renal cell carcinoma","Tourette syndrome","Peripheral arterial disease"]	0	[]	3	["CTD (Renal cell carcinoma)","GWAS catalog (Peripheral arterial disease)","GWAS catalog (Tourette syndrome)"]
LMAN2L	2	["Renal cell carcinoma","Tourette syndrome"]	0	[]	3	["CTD (Renal cell carcinoma)","GenCC (Neurodevelopmental disorder)","GWAS catalog (Tourette syndrome)"]
CCDC7	2	["Tourette syndrome","Peripheral arterial disease"]	0	[]	1	["GWAS catalog (Peripheral arterial disease)"]
MAPK10	2	["Tourette syndrome","Peripheral arterial disease"]	0	[]	2	["GWAS catalog (Peripheral arterial disease)","GWAS catalog (Tourette syndrome)"]

Diseases Linked via Similar Genes

Attention deficit hyperactivity disorder Linked via 3 of 5 related genesKCNH3, ZNF536, LMAN2L Color vision deficiency Linked via 3 of 5 related genesZNF536, CCDC7, MAPK10 Bipolar disorder Linked via 2 of 5 related genesZNF536, LMAN2L Androgenetic alopecia Linked via 1 of 5 related genesZNF536 Hypertension Linked via 1 of 5 related genesZNF536

Disease	Linked Via (Gene Count)	Linked Via (Gene Names)
Attention deficit hyperactivity disorder	3	["KCNH3","ZNF536","LMAN2L"]
Color vision deficiency	3	["ZNF536","CCDC7","MAPK10"]
Bipolar disorder	2	["ZNF536","LMAN2L"]
Androgenetic alopecia	1	["ZNF536"]
Hypertension	1	["ZNF536"]