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Gene Gene information from NCBI Gene database.
Entrez ID 58487
Gene name CREB/ATF bZIP transcription factor
Gene symbol CREBZF
Synonyms (NCBI Gene)
SMILEZF
Chromosome 11
Chromosome location 11q14.1
miRNA miRNA information provided by mirtarbase database.
896 Show/Hide all (896)
miRTarBase ID miRNA Experiments Reference
MIRT016120 hsa-miR-421 Sequencing 20371350
MIRT019586 hsa-miR-340-5p Sequencing 20371350
MIRT003363 hsa-miR-221-3p Reporter assay;Microarray 20018759
MIRT024367 hsa-miR-215-5p Microarray 19074876
MIRT026395 hsa-miR-192-5p Microarray 19074876
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
22 Show/Hide all (22)
GO ID Ontology Definition Evidence Reference
GO:0000785 Component Chromatin ISA
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific ISA
GO:0003677 Function DNA binding NAS 10871379
GO:0003700 Function DNA-binding transcription factor activity IEA
GO:0005515 Function Protein binding IPI 10871379, 15705566, 16343488, 17483474, 18391022, 19690166, 20102225, 23661758, 25416956, 28514442, 32296183, 32911434, 33961781
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
606444 24905 ENSG00000137504
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9NS37
Protein name CREB/ATF bZIP transcription factor (Host cell factor-binding transcription factor Zhangfei) (HCF-binding transcription factor Zhangfei)
Protein function Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00170 bZIP_1 204 → 265 bZIP transcription factor Coiled-coil
Tissue specificity TISSUE SPECIFICITY: In adults, expressed most abundantly in heart, liver and skeletal muscle, moderately abundant in kidney and pancreas, and barely detectable in lung. In fetal tissues, expressed most abundantly in kidney and very low amounts in heart, l
Sequence
MRHSLTKLLAASGSNSPTRSESPEPAATCSLPSDLTRAAAGEEETAAAGSPGRKQQFGDE
GELEAGRGSRGGVAVRAPSPEEMEEEAIASLPGEETEDMDFLSGLELADLLDPRQPDWHL
DPGLSSPGPLSSSGGGSDSGGLWRGDDDDEAAAAEMQRFSDLLQRLLNGIGGCSSSSDSG
SAEKRRRKSPGGGGGGGSGNDNNQAATKSPRKAAAAAARLNRLKKKEYVMGLESRVRGLA
AENQELRAENRELGKRVQALQEESR
YLRAVLANETGLARLLSRLSGVGLRLTTSLFRDSP
AGDHDYALPVGKQKQDLLEEDDSAGGVCLHVDKDKVSVEFCSACARKASSSLKM
Sequence length 354
Interactions View interactions