CPNE2 (copine 2)

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Gene miRNA Gene ontology Other IDs Protein Diseases linked via similar genes

Gene

• Entrez ID: 221184
• Gene name: Copine 2
• Gene symbol: CPNE2
• Synonyms (NCBI Gene): COPN2, CPN2
• Chromosome: 16
• Chromosome location: 16q13
• Summary: Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an in

miRNA Show/Hide all (96)

miRTarBase ID	miRNA	Experiments	Reference
MIRT025805	hsa-miR-7-5p	Microarray	17612493
MIRT025805	hsa-miR-7-5p	Microarray	19073608
MIRT570068	hsa-miR-3125	PAR-CLIP	20371350
MIRT570069	hsa-miR-3916	PAR-CLIP	20371350
MIRT570067	hsa-miR-6859-5p	PAR-CLIP	20371350
MIRT570066	hsa-miR-3150b-3p	PAR-CLIP	20371350
MIRT570065	hsa-miR-4784	PAR-CLIP	20371350
MIRT570064	hsa-miR-671-5p	PAR-CLIP	20371350
MIRT570063	hsa-miR-765	PAR-CLIP	20371350
MIRT570062	hsa-miR-6731-5p	PAR-CLIP	20371350
MIRT570061	hsa-miR-8085	PAR-CLIP	20371350
MIRT570060	hsa-miR-3175	PAR-CLIP	20371350
MIRT570059	hsa-miR-1343-5p	PAR-CLIP	20371350
MIRT570058	hsa-miR-939-5p	PAR-CLIP	20371350
MIRT570056	hsa-miR-6825-5p	PAR-CLIP	20371350
MIRT570057	hsa-miR-92a-2-5p	PAR-CLIP	20371350
MIRT570055	hsa-miR-491-5p	PAR-CLIP	20371350
MIRT570054	hsa-miR-3150a-3p	PAR-CLIP	20371350
MIRT570053	hsa-miR-6763-5p	PAR-CLIP	20371350
MIRT570068	hsa-miR-3125	PAR-CLIP	20371350
MIRT570069	hsa-miR-3916	PAR-CLIP	20371350
MIRT570067	hsa-miR-6859-5p	PAR-CLIP	20371350
MIRT570066	hsa-miR-3150b-3p	PAR-CLIP	20371350
MIRT570065	hsa-miR-4784	PAR-CLIP	20371350
MIRT570064	hsa-miR-671-5p	PAR-CLIP	20371350
MIRT570063	hsa-miR-765	PAR-CLIP	20371350
MIRT570062	hsa-miR-6731-5p	PAR-CLIP	20371350
MIRT570061	hsa-miR-8085	PAR-CLIP	20371350
MIRT570060	hsa-miR-3175	PAR-CLIP	20371350
MIRT570059	hsa-miR-1343-5p	PAR-CLIP	20371350
MIRT570058	hsa-miR-939-5p	PAR-CLIP	20371350
MIRT570056	hsa-miR-6825-5p	PAR-CLIP	20371350
MIRT570057	hsa-miR-92a-2-5p	PAR-CLIP	20371350
MIRT570055	hsa-miR-491-5p	PAR-CLIP	20371350
MIRT570054	hsa-miR-3150a-3p	PAR-CLIP	20371350
MIRT570053	hsa-miR-6763-5p	PAR-CLIP	20371350
MIRT906552	hsa-miR-1207-3p	CLIP-seq
MIRT906553	hsa-miR-1254	CLIP-seq
MIRT906554	hsa-miR-1275	CLIP-seq
MIRT906555	hsa-miR-1285	CLIP-seq
MIRT906556	hsa-miR-1587	CLIP-seq
MIRT906557	hsa-miR-181a	CLIP-seq
MIRT906558	hsa-miR-181b	CLIP-seq
MIRT906559	hsa-miR-181c	CLIP-seq
MIRT906560	hsa-miR-181d	CLIP-seq
MIRT906561	hsa-miR-300	CLIP-seq
MIRT906562	hsa-miR-3065-5p	CLIP-seq
MIRT906563	hsa-miR-3116	CLIP-seq
MIRT906564	hsa-miR-3135b	CLIP-seq
MIRT906565	hsa-miR-3145-5p	CLIP-seq
MIRT906566	hsa-miR-3187-5p	CLIP-seq
MIRT906567	hsa-miR-3652	CLIP-seq
MIRT906568	hsa-miR-3653	CLIP-seq
MIRT906569	hsa-miR-3658	CLIP-seq
MIRT906570	hsa-miR-3689d	CLIP-seq
MIRT906571	hsa-miR-378g	CLIP-seq
MIRT906572	hsa-miR-381	CLIP-seq
MIRT906573	hsa-miR-3973	CLIP-seq
MIRT906574	hsa-miR-421	CLIP-seq
MIRT906575	hsa-miR-4259	CLIP-seq
MIRT906576	hsa-miR-4262	CLIP-seq
MIRT906577	hsa-miR-4282	CLIP-seq
MIRT906578	hsa-miR-4430	CLIP-seq
MIRT906579	hsa-miR-4436b-5p	CLIP-seq
MIRT906580	hsa-miR-4457	CLIP-seq
MIRT906581	hsa-miR-4470	CLIP-seq
MIRT906582	hsa-miR-4492	CLIP-seq
MIRT906583	hsa-miR-4498	CLIP-seq
MIRT906584	hsa-miR-4651	CLIP-seq
MIRT906585	hsa-miR-4656	CLIP-seq
MIRT906586	hsa-miR-4665-5p	CLIP-seq
MIRT906587	hsa-miR-4666-3p	CLIP-seq
MIRT906588	hsa-miR-4675	CLIP-seq
MIRT906589	hsa-miR-4676-5p	CLIP-seq
MIRT906590	hsa-miR-4709-5p	CLIP-seq
MIRT906591	hsa-miR-4717-5p	CLIP-seq
MIRT906592	hsa-miR-4731-5p	CLIP-seq
MIRT906593	hsa-miR-4741	CLIP-seq
MIRT906594	hsa-miR-4753-5p	CLIP-seq
MIRT906595	hsa-miR-4786-3p	CLIP-seq
MIRT906596	hsa-miR-4789-5p	CLIP-seq
MIRT906597	hsa-miR-513c	CLIP-seq
MIRT906598	hsa-miR-514b-5p	CLIP-seq
MIRT906599	hsa-miR-520d-5p	CLIP-seq
MIRT906600	hsa-miR-524-5p	CLIP-seq
MIRT906601	hsa-miR-548k	CLIP-seq
MIRT906602	hsa-miR-575	CLIP-seq
MIRT906603	hsa-miR-608	CLIP-seq
MIRT906604	hsa-miR-612	CLIP-seq
MIRT906605	hsa-miR-671-3p	CLIP-seq
MIRT906606	hsa-miR-762	CLIP-seq
MIRT906607	hsa-miR-939	CLIP-seq
MIRT906562	hsa-miR-3065-5p	CLIP-seq
MIRT906565	hsa-miR-3145-5p	CLIP-seq
MIRT906574	hsa-miR-421	CLIP-seq
MIRT906590	hsa-miR-4709-5p	CLIP-seq

Gene ontology (GO) Show/Hide all (12)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	21044950, 25416956, 32296183, 33961781
GO:0005544	Function	Calcium-dependent phospholipid binding	IBA
GO:0005544	Function	Calcium-dependent phospholipid binding	IEA
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0016020	Component	Membrane	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0070062	Component	Extracellular exosome	HDA	23533145
GO:0071277	Process	Cellular response to calcium ion	IBA
GO:0071277	Process	Cellular response to calcium ion	IEA

Other IDs

• MIM: 604206
• HGNC: 2315
• e!Ensembl: ENSG00000140848

Protein

• UniProt ID: Q96FN4
• Protein name: Copine-2 (Copine II)
• Protein function: Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes. Exhibits calcium-dependent cell membrane binding properties.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00168	C2	25 → 133	C2 domain	Domain
  PF00168	C2	156 → 263	C2 domain	Domain
  PF07002	Copine	326 → 543	Copine	Family

• Tissue specificity: TISSUE SPECIFICITY: Expressed in the brain. Expressed in neutrophil precursors from the bone marrow and peripheral blood (PubMed:12949241).
• Sequence:

  MAHIPSGGAPAAGAAPMGPQYCVCKVELSVSGQNLLDRDVTSKSDPFCVLFTENNGRWIE
  YDRTETAINNLNPAFSKKFVLDYHFEEVQKLKFALFDQDKSSMRLDEHDFLGQFSCSLGT
  IVSSKKITRPLLLLNDKPAGKGLITIAAQELSDNRVITLSLAGRRLDKKDLFGKSDPFLE
  FYKPGDDGKWMLVHRTEVIKYTLDPVWKPFTVPLVSLCDGDMEKPIQVMCYDYDNDGGHD
  FIGEFQTSVSQMCEARDSVPLEFECINPKKQRKKKNYKNSGIIILRSCKINRDYSFLDYI
  LGGCQLMFTVGIDFTASNGNPLDPSSLHYINPMGTNEYLSAIWAVGQIIQDYDSDKMFPA
  LGFGAQLPPDWKVSHEFAINFNPTNPFCSGVDGIAQAYSACLPHIRFYGPTNFSPIVNHV
  ARFAAQATQQRTATQYFILLIITDGVISDMEETRHAVVQASKLPMSIIIVGVGNADFAAM
  EFLDGDSRMLRSHTGEEAARDIVQFVPFREFRNAAKETLAKAVLAELPQQVVQYFKHKNL
  PPTNSEPA

• Sequence length: 548

Related Genes

No strongly related genes found yet for CPNE2.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to CPNE2.