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Gene Gene information from NCBI Gene database.
Entrez ID 8161
Gene name Coilin
Gene symbol COIL
Synonyms (NCBI Gene)
CLN80p80-coilin
Chromosome 17
Chromosome location 17q22
Summary The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and
miRNA miRNA information provided by mirtarbase database.
1083 Show/Hide all (1083)
miRTarBase ID miRNA Experiments Reference
MIRT001376 hsa-miR-1-3p pSILAC 18668040
MIRT001376 hsa-miR-1-3p Proteomics;Other 18668040
MIRT027424 hsa-miR-98-5p Microarray 19088304
MIRT001578 hsa-let-7b-5p Proteomics 18668040
MIRT046608 hsa-miR-222-3p CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
16 Show/Hide all (16)
GO ID Ontology Definition Evidence Reference
GO:0000387 Process Spliceosomal snRNP assembly IBA
GO:0001650 Component Fibrillar center IDA
GO:0005515 Function Protein binding IPI 12757932, 15862129, 16079131, 16713569, 21070772, 21072240, 21920476, 23685356, 25416956, 27107012, 29934401, 31515488, 32296183, 32814053, 33961781, 35271311
GO:0005634 Component Nucleus IDA 19734146
GO:0005634 Component Nucleus IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
600272 2184 ENSG00000121058
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P38432
Protein name Coilin (p80-coilin)
Protein function Component of nuclear coiled bodies, also known as Cajal bodies or CBs, which are involved in the modification and assembly of nucleoplasmic snRNPs.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15862 Coilin_N 7 → 218 Coilin N-terminus Family
Tissue specificity TISSUE SPECIFICITY: Found in all the cell types examined.
Sequence
MAASETVRLRLQFDYPPPATPHCTAFWLLVDLNRCRVVTDLISLIRQRFGFSSGAFLGLY
LEGGLLPPAESARLVRDNDCLRVKLEERGVAENSVVISNGDINLSLRKAKKRAFQLEEGE
ETEPDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNKRKNKATCGTVGDDNEEA
KRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSS
PKGSARNSLVKAKRKGSVSVCS
KESPSSSSESESCDESISDGPSKVTLEARNSSEKLPTELSKEEPSTKNTTADKLAIKLGF
SLTPSKGKTSGTTSSSSDSSAESDDQCLMSSSTPECAAGFLKTVGLFAGRGRPGPGLSSQ
TAGAAGWRRSGSNGGGQAPGASPSVSLPASLGRGWGREENLFSWKGAKGRGMRGRGRGRG
HPVSCVVNRSTDNQRQQQLNDVVKNSSTIIQNPVETPKKDYSLLPLLAAAPQVGEKIAFK
LLELTSSYSPDVSDYKEGRILSHNPETQQVDIEILSSLPALREPGKFDLVYHNENGAEVV
EYAVTQESKITVFWKELIDPRLIIESPSNTSSTEPA
Sequence length 576
Interactions View interactions