CNTD1 (cyclin N-terminal domain containing 1)

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Gene miRNA Gene ontology Other IDs Protein Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 124817
• Gene name: Cyclin N-terminal domain containing 1
• Gene symbol: CNTD1
• Synonyms (NCBI Gene): CNTD, COSA1
• Chromosome: 17
• Chromosome location: 17q21.2-q21.31

miRNA Show/Hide all (220)

miRTarBase ID	miRNA	Experiments	Reference
MIRT901498	hsa-miR-125a-5p	CLIP-seq
MIRT901499	hsa-miR-125b	CLIP-seq
MIRT901500	hsa-miR-129-3p	CLIP-seq
MIRT901501	hsa-miR-3134	CLIP-seq
MIRT901502	hsa-miR-3189-3p	CLIP-seq
MIRT901503	hsa-miR-3198	CLIP-seq
MIRT901504	hsa-miR-3607-5p	CLIP-seq
MIRT901505	hsa-miR-409-3p	CLIP-seq
MIRT901506	hsa-miR-4309	CLIP-seq
MIRT901507	hsa-miR-4319	CLIP-seq
MIRT901508	hsa-miR-432	CLIP-seq
MIRT901509	hsa-miR-4446-5p	CLIP-seq
MIRT901510	hsa-miR-4534	CLIP-seq
MIRT901511	hsa-miR-4540	CLIP-seq
MIRT901512	hsa-miR-4661-3p	CLIP-seq
MIRT901513	hsa-miR-4732-3p	CLIP-seq
MIRT901514	hsa-miR-4755-5p	CLIP-seq
MIRT901515	hsa-miR-4786-3p	CLIP-seq
MIRT901516	hsa-miR-554	CLIP-seq
MIRT901517	hsa-miR-619	CLIP-seq
MIRT901518	hsa-miR-670	CLIP-seq
MIRT1967423	hsa-miR-1267	CLIP-seq
MIRT1967424	hsa-miR-1278	CLIP-seq
MIRT1967425	hsa-miR-1303	CLIP-seq
MIRT1967426	hsa-miR-3149	CLIP-seq
MIRT1967427	hsa-miR-3192	CLIP-seq
MIRT1967428	hsa-miR-3662	CLIP-seq
MIRT1967429	hsa-miR-4314	CLIP-seq
MIRT1967430	hsa-miR-4646-5p	CLIP-seq
MIRT1967431	hsa-miR-4652-3p	CLIP-seq
MIRT1967432	hsa-miR-4738-3p	CLIP-seq
MIRT1967433	hsa-miR-4778-5p	CLIP-seq
MIRT1967434	hsa-miR-630	CLIP-seq
MIRT1967435	hsa-miR-653	CLIP-seq
MIRT1967425	hsa-miR-1303	CLIP-seq
MIRT2203097	hsa-miR-3152-3p	CLIP-seq
MIRT2203098	hsa-miR-3194-3p	CLIP-seq
MIRT2203099	hsa-miR-4431	CLIP-seq
MIRT2203100	hsa-miR-4522	CLIP-seq
MIRT2203101	hsa-miR-767-3p	CLIP-seq
MIRT1967426	hsa-miR-3149	CLIP-seq
MIRT1967427	hsa-miR-3192	CLIP-seq
MIRT1967429	hsa-miR-4314	CLIP-seq
MIRT1967430	hsa-miR-4646-5p	CLIP-seq
MIRT1967433	hsa-miR-4778-5p	CLIP-seq
MIRT1967434	hsa-miR-630	CLIP-seq
MIRT1967423	hsa-miR-1267	CLIP-seq
MIRT1967425	hsa-miR-1303	CLIP-seq
MIRT1967431	hsa-miR-4652-3p	CLIP-seq
MIRT1967432	hsa-miR-4738-3p	CLIP-seq
MIRT1967433	hsa-miR-4778-5p	CLIP-seq
MIRT1967435	hsa-miR-653	CLIP-seq
MIRT2447373	hsa-miR-1185	CLIP-seq
MIRT2447374	hsa-miR-1202	CLIP-seq
MIRT2447375	hsa-miR-1261	CLIP-seq
MIRT2447376	hsa-miR-1273f	CLIP-seq
MIRT2447377	hsa-miR-143	CLIP-seq
MIRT2447378	hsa-miR-190	CLIP-seq
MIRT2447379	hsa-miR-190b	CLIP-seq
MIRT2447380	hsa-miR-204	CLIP-seq
MIRT2447381	hsa-miR-2052	CLIP-seq
MIRT2447382	hsa-miR-211	CLIP-seq
MIRT2447383	hsa-miR-223	CLIP-seq
MIRT2447384	hsa-miR-299-3p	CLIP-seq
MIRT2447385	hsa-miR-3153	CLIP-seq
MIRT2447386	hsa-miR-3180-5p	CLIP-seq
MIRT2447387	hsa-miR-3194-5p	CLIP-seq
MIRT2447388	hsa-miR-3201	CLIP-seq
MIRT2447389	hsa-miR-3605-5p	CLIP-seq
MIRT2447390	hsa-miR-3679-5p	CLIP-seq
MIRT2447391	hsa-miR-3972	CLIP-seq
MIRT2447392	hsa-miR-4307	CLIP-seq
MIRT2447393	hsa-miR-4328	CLIP-seq
MIRT901509	hsa-miR-4446-5p	CLIP-seq
MIRT2447394	hsa-miR-4648	CLIP-seq
MIRT2447395	hsa-miR-4654	CLIP-seq
MIRT2447396	hsa-miR-4668-5p	CLIP-seq
MIRT2447397	hsa-miR-4708-5p	CLIP-seq
MIRT901514	hsa-miR-4755-5p	CLIP-seq
MIRT2447398	hsa-miR-4769-5p	CLIP-seq
MIRT2447399	hsa-miR-4770	CLIP-seq
MIRT2447400	hsa-miR-4791	CLIP-seq
MIRT2447401	hsa-miR-520a-5p	CLIP-seq
MIRT2447402	hsa-miR-525-5p	CLIP-seq
MIRT2447403	hsa-miR-623	CLIP-seq
MIRT2447373	hsa-miR-1185	CLIP-seq
MIRT2447374	hsa-miR-1202	CLIP-seq
MIRT2447376	hsa-miR-1273f	CLIP-seq
MIRT2447377	hsa-miR-143	CLIP-seq
MIRT2447378	hsa-miR-190	CLIP-seq
MIRT2447379	hsa-miR-190b	CLIP-seq
MIRT2447380	hsa-miR-204	CLIP-seq
MIRT2447381	hsa-miR-2052	CLIP-seq
MIRT2447382	hsa-miR-211	CLIP-seq
MIRT2447383	hsa-miR-223	CLIP-seq
MIRT2447386	hsa-miR-3180-5p	CLIP-seq
MIRT2447387	hsa-miR-3194-5p	CLIP-seq
MIRT2447388	hsa-miR-3201	CLIP-seq
MIRT2447389	hsa-miR-3605-5p	CLIP-seq
MIRT2447390	hsa-miR-3679-5p	CLIP-seq
MIRT2447391	hsa-miR-3972	CLIP-seq
MIRT2447392	hsa-miR-4307	CLIP-seq
MIRT2447393	hsa-miR-4328	CLIP-seq
MIRT901509	hsa-miR-4446-5p	CLIP-seq
MIRT2447397	hsa-miR-4708-5p	CLIP-seq
MIRT901514	hsa-miR-4755-5p	CLIP-seq
MIRT2447399	hsa-miR-4770	CLIP-seq
MIRT2447400	hsa-miR-4791	CLIP-seq
MIRT2447401	hsa-miR-520a-5p	CLIP-seq
MIRT2447402	hsa-miR-525-5p	CLIP-seq
MIRT2447403	hsa-miR-623	CLIP-seq
MIRT2447373	hsa-miR-1185	CLIP-seq
MIRT2447374	hsa-miR-1202	CLIP-seq
MIRT2506117	hsa-miR-1245b-3p	CLIP-seq
MIRT2447375	hsa-miR-1261	CLIP-seq
MIRT2506118	hsa-miR-1273e	CLIP-seq
MIRT2447376	hsa-miR-1273f	CLIP-seq
MIRT2506119	hsa-miR-141	CLIP-seq
MIRT2447377	hsa-miR-143	CLIP-seq
MIRT2447378	hsa-miR-190	CLIP-seq
MIRT2447379	hsa-miR-190b	CLIP-seq
MIRT2506120	hsa-miR-200a	CLIP-seq
MIRT2506121	hsa-miR-203	CLIP-seq
MIRT2447380	hsa-miR-204	CLIP-seq
MIRT2447381	hsa-miR-2052	CLIP-seq
MIRT2447382	hsa-miR-211	CLIP-seq
MIRT2447383	hsa-miR-223	CLIP-seq
MIRT2447384	hsa-miR-299-3p	CLIP-seq
MIRT2506122	hsa-miR-3129-3p	CLIP-seq
MIRT2506123	hsa-miR-3140-3p	CLIP-seq
MIRT2447385	hsa-miR-3153	CLIP-seq
MIRT2447386	hsa-miR-3180-5p	CLIP-seq
MIRT2447387	hsa-miR-3194-5p	CLIP-seq
MIRT2447388	hsa-miR-3201	CLIP-seq
MIRT2447389	hsa-miR-3605-5p	CLIP-seq
MIRT901504	hsa-miR-3607-5p	CLIP-seq
MIRT2447390	hsa-miR-3679-5p	CLIP-seq
MIRT2506124	hsa-miR-383	CLIP-seq
MIRT2506125	hsa-miR-3913-3p	CLIP-seq
MIRT2506126	hsa-miR-3921	CLIP-seq
MIRT2447391	hsa-miR-3972	CLIP-seq
MIRT2447392	hsa-miR-4307	CLIP-seq
MIRT2447393	hsa-miR-4328	CLIP-seq
MIRT901509	hsa-miR-4446-5p	CLIP-seq
MIRT2447394	hsa-miR-4648	CLIP-seq
MIRT2506127	hsa-miR-4653-5p	CLIP-seq
MIRT2447395	hsa-miR-4654	CLIP-seq
MIRT2506128	hsa-miR-4659a-3p	CLIP-seq
MIRT2506129	hsa-miR-4659b-3p	CLIP-seq
MIRT2447396	hsa-miR-4668-5p	CLIP-seq
MIRT2447397	hsa-miR-4708-5p	CLIP-seq
MIRT2506130	hsa-miR-4735-5p	CLIP-seq
MIRT901514	hsa-miR-4755-5p	CLIP-seq
MIRT2506131	hsa-miR-4766-5p	CLIP-seq
MIRT2447398	hsa-miR-4769-5p	CLIP-seq
MIRT2447399	hsa-miR-4770	CLIP-seq
MIRT2506132	hsa-miR-4772-5p	CLIP-seq
MIRT2447400	hsa-miR-4791	CLIP-seq
MIRT2506133	hsa-miR-489	CLIP-seq
MIRT2506134	hsa-miR-513a-3p	CLIP-seq
MIRT2447401	hsa-miR-520a-5p	CLIP-seq
MIRT2447402	hsa-miR-525-5p	CLIP-seq
MIRT2506135	hsa-miR-548ae	CLIP-seq
MIRT2506136	hsa-miR-548aj	CLIP-seq
MIRT2506137	hsa-miR-548am	CLIP-seq
MIRT2506138	hsa-miR-548x	CLIP-seq
MIRT901517	hsa-miR-619	CLIP-seq
MIRT2447403	hsa-miR-623	CLIP-seq
MIRT2506139	hsa-miR-942	CLIP-seq
MIRT2447373	hsa-miR-1185	CLIP-seq
MIRT2447374	hsa-miR-1202	CLIP-seq
MIRT2506117	hsa-miR-1245b-3p	CLIP-seq
MIRT2447375	hsa-miR-1261	CLIP-seq
MIRT2506118	hsa-miR-1273e	CLIP-seq
MIRT2447376	hsa-miR-1273f	CLIP-seq
MIRT2447377	hsa-miR-143	CLIP-seq
MIRT2447378	hsa-miR-190	CLIP-seq
MIRT2447379	hsa-miR-190b	CLIP-seq
MIRT2506121	hsa-miR-203	CLIP-seq
MIRT2447380	hsa-miR-204	CLIP-seq
MIRT2447381	hsa-miR-2052	CLIP-seq
MIRT2447382	hsa-miR-211	CLIP-seq
MIRT2447383	hsa-miR-223	CLIP-seq
MIRT2447384	hsa-miR-299-3p	CLIP-seq
MIRT2506122	hsa-miR-3129-3p	CLIP-seq
MIRT2506123	hsa-miR-3140-3p	CLIP-seq
MIRT2447386	hsa-miR-3180-5p	CLIP-seq
MIRT2447387	hsa-miR-3194-5p	CLIP-seq
MIRT2447388	hsa-miR-3201	CLIP-seq
MIRT2447389	hsa-miR-3605-5p	CLIP-seq
MIRT901504	hsa-miR-3607-5p	CLIP-seq
MIRT2447390	hsa-miR-3679-5p	CLIP-seq
MIRT2506124	hsa-miR-383	CLIP-seq
MIRT2506125	hsa-miR-3913-3p	CLIP-seq
MIRT2506126	hsa-miR-3921	CLIP-seq
MIRT2447391	hsa-miR-3972	CLIP-seq
MIRT2447392	hsa-miR-4307	CLIP-seq
MIRT2447393	hsa-miR-4328	CLIP-seq
MIRT901509	hsa-miR-4446-5p	CLIP-seq
MIRT2506127	hsa-miR-4653-5p	CLIP-seq
MIRT2506128	hsa-miR-4659a-3p	CLIP-seq
MIRT2506129	hsa-miR-4659b-3p	CLIP-seq
MIRT2447397	hsa-miR-4708-5p	CLIP-seq
MIRT2506130	hsa-miR-4735-5p	CLIP-seq
MIRT901514	hsa-miR-4755-5p	CLIP-seq
MIRT2506131	hsa-miR-4766-5p	CLIP-seq
MIRT2447399	hsa-miR-4770	CLIP-seq
MIRT2506132	hsa-miR-4772-5p	CLIP-seq
MIRT2447400	hsa-miR-4791	CLIP-seq
MIRT2506133	hsa-miR-489	CLIP-seq
MIRT2506134	hsa-miR-513a-3p	CLIP-seq
MIRT2447401	hsa-miR-520a-5p	CLIP-seq
MIRT2447402	hsa-miR-525-5p	CLIP-seq
MIRT2506135	hsa-miR-548ae	CLIP-seq
MIRT2506136	hsa-miR-548aj	CLIP-seq
MIRT2506137	hsa-miR-548am	CLIP-seq
MIRT2506138	hsa-miR-548x	CLIP-seq
MIRT901517	hsa-miR-619	CLIP-seq
MIRT2447403	hsa-miR-623	CLIP-seq
MIRT2506139	hsa-miR-942	CLIP-seq

Gene ontology (GO) Show/Hide all (11)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005634	Component	Nucleus	IEA
GO:0005694	Component	Chromosome	IEA
GO:0005694	Component	Chromosome	ISS
GO:0005737	Component	Cytoplasm	IEA
GO:0007131	Process	Reciprocal meiotic recombination	IBA
GO:0007131	Process	Reciprocal meiotic recombination	IEA
GO:0007283	Process	Spermatogenesis	IEA
GO:0035861	Component	Site of double-strand break	IBA
GO:0051321	Process	Meiotic cell cycle	IEA
GO:0051445	Process	Regulation of meiotic cell cycle	IEA
GO:0051445	Process	Regulation of meiotic cell cycle	ISS

Other IDs

• MIM: 618166
• HGNC: 26847
• e!Ensembl: ENSG00000176563

Protein

• UniProt ID: Q8N815
• Protein name: Cyclin N-terminal domain-containing protein 1
• Protein function: Plays a role in the different steps of crossover formation during meiotic recombination. Participates in the crossover differentiation step of crossover-specific recombination intermediates through its interaction with PRR19. In addition, stimul
• Sequence:

  MDGPMRPRSASLVDFQFGVVATETIEDALLHLAQQNEQAVREASGRLGRFREPQIVEFVF
  LLSEQWCLEKSVSYQAVEILERFMVKQAENICRQATIQPRDNKRESQNWRALKQQLVNKF
  TLRLVSCVQLASKLSFRNKIISNITVLNFLQALGYLHTKEELLESELDVLKSLNFRINLP
  TPLAYVETLLEVLGYNGCLVPAMRLHATCLTLLDLVYLLHEPIYESLLRASIENSTPSQL
  QGEKFTSVKEDFMLLAVGIIAASAFIQNHECWSQVVGHLQSITGIALASIAEFSYAILTH
  GVGANTPGRQQSIPPHLAARALKTVASSNT

• Sequence length: 330

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
BREAST CANCER	—	GWAS catalog	29059683	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BREAST CARCINOMA	—	GWAS catalog	29059683	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Breast Carcinoma	Breast Carcinoma	GWASCAT_DG	29059683		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Vasculitis	Vasculitis	Pubtator	34961976	Associate	★☆☆☆☆ Found in Text Mining only

Related Genes

No strongly related genes found yet for CNTD1.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to CNTD1.