CLECL1 (C-type lectin like 1)

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Gene Gene information from NCBI Gene database.
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Entrez ID 160365
Gene name C-type lectin like 1
Gene symbol CLECL1
Synonyms (NCBI Gene)
CLECL1PDCAL-1DCAL1
Chromosome 12
Chromosome location 12p13.31
Summary This gene encodes a type II transmembrane, C-type lectin-like protein that is highly expressed on dendritic and B cells. This protein may act as a T-cell costimulatory molecule that enhances interleukin-4 production, and maybe involved in the regulation o
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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GO ID Ontology Definition Evidence Reference
GO:0005886 Component Plasma membrane IDA 12421943
GO:0005886 Component Plasma membrane IEA
GO:0016020 Component Membrane IEA
GO:0030246 Function Carbohydrate binding IEA
GO:0032753 Process Positive regulation of interleukin-4 production IDA 12421943
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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MIM HGNC e!Ensembl
607467 24462 HGNC
Protein Protein information from UniProt database.
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UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8IZS7
Protein name Putative C-type lectin-like domain family 1 (C-type lectin-like domain family 1 pseudogene) (Dendritic cell-associated lectin 1) (DC-associated lectin-1) (DCAL-1)
Protein function May function in mediating immune cell-cell interactions. May act as a T-cell costimulatory molecule, enhancing anti-CD3-induced proliferation. May play a role in the interaction of dendritic cells with T-cells and the cells of the adaptive immun
Family and domains
Tissue specificity TISSUE SPECIFICITY: Expressed in spleen, lymph node, and tonsil. Lower expression in peripheral blood, bone marrow, and colon. No expression detected in thymus. Highly expressed in dendritic and B-cells. {ECO:0000269|PubMed:12421943}.
Sequence 
MVSNFFHVIQVFEKSATLISKTEHIGFVIYSWRKSTTHLGSRRKFAISIYLSEVSLQKYD
CPFSGTSFVVFSLFLICAMAGDVVYADIKTVRTSPLELAFPLQRSVSFNFSTVHKSCPAK
DWKVHKGKCYWIAETKKSWNKSQNDCAINNSYLMVIQDITAMVRFNI
Sequence length 167
Interactions View interactions

No strongly related genes found yet for CLECL1.

No additional diseases found yet through genes similar to CLECL1.