CKAP2 (cytoskeleton associated protein 2)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 26586
• Gene name: Cytoskeleton associated protein 2
• Gene symbol: CKAP2
• Synonyms (NCBI Gene): LB1, TMAP, se20-10
• Chromosome: 13
• Chromosome location: 13q14.3
• Summary: This gene encodes a cytoskeleton-associated protein that stabalizes microtubules and plays a role in the regulation of cell division. The encoded protein is itself regulated through phosphorylation at multiple serine and threonine residues. There is a pse

miRNA Show/Hide all (267)

miRTarBase ID	miRNA	Experiments	Reference
MIRT019751	hsa-miR-375	Microarray	20215506
MIRT052226	hsa-let-7b-5p	CLASH	23622248
MIRT048321	hsa-miR-106a-5p	CLASH	23622248
MIRT046745	hsa-miR-222-3p	CLASH	23622248
MIRT571023	hsa-miR-3609	PAR-CLIP	20371350
MIRT571022	hsa-miR-548ah-5p	PAR-CLIP	20371350
MIRT048321	hsa-miR-106a-5p	PAR-CLIP	20371350
MIRT571021	hsa-miR-106b-5p	PAR-CLIP	20371350
MIRT571020	hsa-miR-17-5p	PAR-CLIP	20371350
MIRT571019	hsa-miR-20a-5p	PAR-CLIP	20371350
MIRT571018	hsa-miR-20b-5p	PAR-CLIP	20371350
MIRT571017	hsa-miR-519d-3p	PAR-CLIP	20371350
MIRT571016	hsa-miR-526b-3p	PAR-CLIP	20371350
MIRT571015	hsa-miR-93-5p	PAR-CLIP	20371350
MIRT571014	hsa-miR-4796-3p	PAR-CLIP	20371350
MIRT571013	hsa-miR-490-3p	PAR-CLIP	20371350
MIRT571012	hsa-miR-649	PAR-CLIP	20371350
MIRT571011	hsa-miR-6755-5p	PAR-CLIP	20371350
MIRT571023	hsa-miR-3609	PAR-CLIP	20371350
MIRT571022	hsa-miR-548ah-5p	PAR-CLIP	20371350
MIRT048321	hsa-miR-106a-5p	PAR-CLIP	20371350
MIRT571021	hsa-miR-106b-5p	PAR-CLIP	20371350
MIRT571020	hsa-miR-17-5p	PAR-CLIP	20371350
MIRT571019	hsa-miR-20a-5p	PAR-CLIP	20371350
MIRT571018	hsa-miR-20b-5p	PAR-CLIP	20371350
MIRT571017	hsa-miR-519d-3p	PAR-CLIP	20371350
MIRT571016	hsa-miR-526b-3p	PAR-CLIP	20371350
MIRT571015	hsa-miR-93-5p	PAR-CLIP	20371350
MIRT571014	hsa-miR-4796-3p	PAR-CLIP	20371350
MIRT571013	hsa-miR-490-3p	PAR-CLIP	20371350
MIRT571012	hsa-miR-649	PAR-CLIP	20371350
MIRT571011	hsa-miR-6755-5p	PAR-CLIP	20371350
MIRT894074	hsa-miR-1251	CLIP-seq
MIRT894075	hsa-miR-1253	CLIP-seq
MIRT894076	hsa-miR-28-5p	CLIP-seq
MIRT894077	hsa-miR-3074-3p	CLIP-seq
MIRT894078	hsa-miR-3125	CLIP-seq
MIRT894079	hsa-miR-3139	CLIP-seq
MIRT894080	hsa-miR-3613-3p	CLIP-seq
MIRT894081	hsa-miR-3647-3p	CLIP-seq
MIRT894082	hsa-miR-3668	CLIP-seq
MIRT894083	hsa-miR-3669	CLIP-seq
MIRT894084	hsa-miR-3670	CLIP-seq
MIRT894085	hsa-miR-3916	CLIP-seq
MIRT894086	hsa-miR-3925-5p	CLIP-seq
MIRT894087	hsa-miR-4272	CLIP-seq
MIRT894088	hsa-miR-4475	CLIP-seq
MIRT894089	hsa-miR-4502	CLIP-seq
MIRT894090	hsa-miR-4503	CLIP-seq
MIRT894091	hsa-miR-4659a-5p	CLIP-seq
MIRT894092	hsa-miR-4659b-5p	CLIP-seq
MIRT894093	hsa-miR-4690-5p	CLIP-seq
MIRT894094	hsa-miR-4731-3p	CLIP-seq
MIRT894095	hsa-miR-4732-5p	CLIP-seq
MIRT894096	hsa-miR-4762-5p	CLIP-seq
MIRT894097	hsa-miR-4773	CLIP-seq
MIRT894098	hsa-miR-4776-3p	CLIP-seq
MIRT894099	hsa-miR-4801	CLIP-seq
MIRT894100	hsa-miR-548ac	CLIP-seq
MIRT894101	hsa-miR-548d-3p	CLIP-seq
MIRT894102	hsa-miR-548n	CLIP-seq
MIRT894103	hsa-miR-548t	CLIP-seq
MIRT894104	hsa-miR-548z	CLIP-seq
MIRT894105	hsa-miR-549	CLIP-seq
MIRT894106	hsa-miR-555	CLIP-seq
MIRT894107	hsa-miR-595	CLIP-seq
MIRT894108	hsa-miR-600	CLIP-seq
MIRT894109	hsa-miR-602	CLIP-seq
MIRT894110	hsa-miR-607	CLIP-seq
MIRT894111	hsa-miR-708	CLIP-seq
MIRT894112	hsa-miR-877	CLIP-seq
MIRT894113	hsa-miR-3973	CLIP-seq
MIRT894114	hsa-miR-4753-3p	CLIP-seq
MIRT894115	hsa-miR-548l	CLIP-seq
MIRT894116	hsa-miR-935	CLIP-seq
MIRT894117	hsa-miR-942	CLIP-seq
MIRT1965056	hsa-miR-1207-5p	CLIP-seq
MIRT1965057	hsa-miR-1208	CLIP-seq
MIRT894074	hsa-miR-1251	CLIP-seq
MIRT894075	hsa-miR-1253	CLIP-seq
MIRT1965058	hsa-miR-1305	CLIP-seq
MIRT1965059	hsa-miR-1321	CLIP-seq
MIRT1965060	hsa-miR-181a	CLIP-seq
MIRT1965061	hsa-miR-181b	CLIP-seq
MIRT1965062	hsa-miR-181c	CLIP-seq
MIRT1965063	hsa-miR-181d	CLIP-seq
MIRT1965064	hsa-miR-217	CLIP-seq
MIRT1965065	hsa-miR-2682	CLIP-seq
MIRT894077	hsa-miR-3074-3p	CLIP-seq
MIRT1965066	hsa-miR-3129-3p	CLIP-seq
MIRT1965067	hsa-miR-3166	CLIP-seq
MIRT894083	hsa-miR-3669	CLIP-seq
MIRT1965068	hsa-miR-3714	CLIP-seq
MIRT894086	hsa-miR-3925-5p	CLIP-seq
MIRT894113	hsa-miR-3973	CLIP-seq
MIRT1965069	hsa-miR-421	CLIP-seq
MIRT1965070	hsa-miR-4262	CLIP-seq
MIRT1965071	hsa-miR-4270	CLIP-seq
MIRT1965072	hsa-miR-4328	CLIP-seq
MIRT1965073	hsa-miR-4420	CLIP-seq
MIRT1965074	hsa-miR-4441	CLIP-seq
MIRT894088	hsa-miR-4475	CLIP-seq
MIRT1965075	hsa-miR-4484	CLIP-seq
MIRT1965076	hsa-miR-449c	CLIP-seq
MIRT1965077	hsa-miR-4514	CLIP-seq
MIRT1965078	hsa-miR-455-3p	CLIP-seq
MIRT1965079	hsa-miR-4652-3p	CLIP-seq
MIRT894091	hsa-miR-4659a-5p	CLIP-seq
MIRT894092	hsa-miR-4659b-5p	CLIP-seq
MIRT1965080	hsa-miR-4692	CLIP-seq
MIRT1965081	hsa-miR-4705	CLIP-seq
MIRT1965082	hsa-miR-4709-5p	CLIP-seq
MIRT894094	hsa-miR-4731-3p	CLIP-seq
MIRT1965083	hsa-miR-4739	CLIP-seq
MIRT894114	hsa-miR-4753-3p	CLIP-seq
MIRT1965084	hsa-miR-4756-5p	CLIP-seq
MIRT1965085	hsa-miR-4763-3p	CLIP-seq
MIRT894097	hsa-miR-4773	CLIP-seq
MIRT894098	hsa-miR-4776-3p	CLIP-seq
MIRT1965086	hsa-miR-4778-5p	CLIP-seq
MIRT894099	hsa-miR-4801	CLIP-seq
MIRT1965087	hsa-miR-485-3p	CLIP-seq
MIRT1965088	hsa-miR-499-3p	CLIP-seq
MIRT1965089	hsa-miR-499a-3p	CLIP-seq
MIRT894100	hsa-miR-548ac	CLIP-seq
MIRT1965090	hsa-miR-548ae	CLIP-seq
MIRT1965091	hsa-miR-548aj	CLIP-seq
MIRT1965092	hsa-miR-548am	CLIP-seq
MIRT1965093	hsa-miR-548an	CLIP-seq
MIRT894101	hsa-miR-548d-3p	CLIP-seq
MIRT1965094	hsa-miR-548g	CLIP-seq
MIRT894115	hsa-miR-548l	CLIP-seq
MIRT894102	hsa-miR-548n	CLIP-seq
MIRT894103	hsa-miR-548t	CLIP-seq
MIRT1965095	hsa-miR-548x	CLIP-seq
MIRT894104	hsa-miR-548z	CLIP-seq
MIRT1965096	hsa-miR-568	CLIP-seq
MIRT1965097	hsa-miR-582-5p	CLIP-seq
MIRT1965098	hsa-miR-587	CLIP-seq
MIRT894109	hsa-miR-602	CLIP-seq
MIRT894110	hsa-miR-607	CLIP-seq
MIRT1965099	hsa-miR-940	CLIP-seq
MIRT894117	hsa-miR-942	CLIP-seq
MIRT2201092	hsa-miR-1257	CLIP-seq
MIRT2201093	hsa-miR-374a	CLIP-seq
MIRT2201094	hsa-miR-374b	CLIP-seq
MIRT2201095	hsa-miR-376c	CLIP-seq
MIRT2201096	hsa-miR-3926	CLIP-seq
MIRT894091	hsa-miR-4659a-5p	CLIP-seq
MIRT894092	hsa-miR-4659b-5p	CLIP-seq
MIRT894098	hsa-miR-4776-3p	CLIP-seq
MIRT2201097	hsa-miR-4802-3p	CLIP-seq
MIRT2201098	hsa-miR-508-5p	CLIP-seq
MIRT2201099	hsa-miR-548s	CLIP-seq
MIRT2201100	hsa-miR-651	CLIP-seq
MIRT2503832	hsa-miR-1183	CLIP-seq
MIRT2503833	hsa-miR-1248	CLIP-seq
MIRT2201092	hsa-miR-1257	CLIP-seq
MIRT2503834	hsa-miR-136	CLIP-seq
MIRT2503835	hsa-miR-140-5p	CLIP-seq
MIRT2503836	hsa-miR-142-5p	CLIP-seq
MIRT2503837	hsa-miR-147	CLIP-seq
MIRT2503838	hsa-miR-190	CLIP-seq
MIRT2503839	hsa-miR-190b	CLIP-seq
MIRT2503840	hsa-miR-2116	CLIP-seq
MIRT2503841	hsa-miR-219-1-3p	CLIP-seq
MIRT894076	hsa-miR-28-5p	CLIP-seq
MIRT2503842	hsa-miR-302f	CLIP-seq
MIRT2503843	hsa-miR-3124-3p	CLIP-seq
MIRT894078	hsa-miR-3125	CLIP-seq
MIRT894079	hsa-miR-3139	CLIP-seq
MIRT2503844	hsa-miR-3159	CLIP-seq
MIRT2503845	hsa-miR-320a	CLIP-seq
MIRT2503846	hsa-miR-320b	CLIP-seq
MIRT2503847	hsa-miR-320c	CLIP-seq
MIRT2503848	hsa-miR-320d	CLIP-seq
MIRT2503849	hsa-miR-340	CLIP-seq
MIRT2503850	hsa-miR-3545-5p	CLIP-seq
MIRT2503851	hsa-miR-3591-5p	CLIP-seq
MIRT894082	hsa-miR-3668	CLIP-seq
MIRT894084	hsa-miR-3670	CLIP-seq
MIRT2201093	hsa-miR-374a	CLIP-seq
MIRT2201094	hsa-miR-374b	CLIP-seq
MIRT2201095	hsa-miR-376c	CLIP-seq
MIRT2503852	hsa-miR-3911	CLIP-seq
MIRT894085	hsa-miR-3916	CLIP-seq
MIRT2201096	hsa-miR-3926	CLIP-seq
MIRT2503853	hsa-miR-3941	CLIP-seq
MIRT2503854	hsa-miR-3942-5p	CLIP-seq
MIRT894113	hsa-miR-3973	CLIP-seq
MIRT2503855	hsa-miR-4429	CLIP-seq
MIRT2503856	hsa-miR-4446-5p	CLIP-seq
MIRT2503857	hsa-miR-4460	CLIP-seq
MIRT894091	hsa-miR-4659a-5p	CLIP-seq
MIRT894092	hsa-miR-4659b-5p	CLIP-seq
MIRT2503858	hsa-miR-466	CLIP-seq
MIRT2503859	hsa-miR-4670-3p	CLIP-seq
MIRT2503860	hsa-miR-4672	CLIP-seq
MIRT2503861	hsa-miR-4677-5p	CLIP-seq
MIRT2503862	hsa-miR-4694-5p	CLIP-seq
MIRT2503863	hsa-miR-4703-5p	CLIP-seq
MIRT2503864	hsa-miR-4717-5p	CLIP-seq
MIRT2503865	hsa-miR-4720-3p	CLIP-seq
MIRT2503866	hsa-miR-4727-3p	CLIP-seq
MIRT894094	hsa-miR-4731-3p	CLIP-seq
MIRT894095	hsa-miR-4732-5p	CLIP-seq
MIRT2503867	hsa-miR-4735-5p	CLIP-seq
MIRT2503868	hsa-miR-4738-3p	CLIP-seq
MIRT894114	hsa-miR-4753-3p	CLIP-seq
MIRT2503869	hsa-miR-4755-5p	CLIP-seq
MIRT2503870	hsa-miR-4764-3p	CLIP-seq
MIRT894098	hsa-miR-4776-3p	CLIP-seq
MIRT894099	hsa-miR-4801	CLIP-seq
MIRT2201097	hsa-miR-4802-3p	CLIP-seq
MIRT2503871	hsa-miR-4804-3p	CLIP-seq
MIRT2201098	hsa-miR-508-5p	CLIP-seq
MIRT2503872	hsa-miR-520d-5p	CLIP-seq
MIRT2503873	hsa-miR-524-5p	CLIP-seq
MIRT894100	hsa-miR-548ac	CLIP-seq
MIRT1965090	hsa-miR-548ae	CLIP-seq
MIRT1965091	hsa-miR-548aj	CLIP-seq
MIRT1965092	hsa-miR-548am	CLIP-seq
MIRT894101	hsa-miR-548d-3p	CLIP-seq
MIRT1965094	hsa-miR-548g	CLIP-seq
MIRT894115	hsa-miR-548l	CLIP-seq
MIRT2201099	hsa-miR-548s	CLIP-seq
MIRT1965095	hsa-miR-548x	CLIP-seq
MIRT894104	hsa-miR-548z	CLIP-seq
MIRT894105	hsa-miR-549	CLIP-seq
MIRT2503874	hsa-miR-576-5p	CLIP-seq
MIRT2503875	hsa-miR-583	CLIP-seq
MIRT2503876	hsa-miR-624	CLIP-seq
MIRT2503877	hsa-miR-644	CLIP-seq
MIRT2201100	hsa-miR-651	CLIP-seq
MIRT894111	hsa-miR-708	CLIP-seq
MIRT894112	hsa-miR-877	CLIP-seq
MIRT894117	hsa-miR-942	CLIP-seq
MIRT2503833	hsa-miR-1248	CLIP-seq
MIRT2201092	hsa-miR-1257	CLIP-seq
MIRT894076	hsa-miR-28-5p	CLIP-seq
MIRT894078	hsa-miR-3125	CLIP-seq
MIRT894079	hsa-miR-3139	CLIP-seq
MIRT2503844	hsa-miR-3159	CLIP-seq
MIRT894082	hsa-miR-3668	CLIP-seq
MIRT894084	hsa-miR-3670	CLIP-seq
MIRT2201093	hsa-miR-374a	CLIP-seq
MIRT2201094	hsa-miR-374b	CLIP-seq
MIRT2201095	hsa-miR-376c	CLIP-seq
MIRT894085	hsa-miR-3916	CLIP-seq
MIRT2503853	hsa-miR-3941	CLIP-seq
MIRT894113	hsa-miR-3973	CLIP-seq
MIRT894091	hsa-miR-4659a-5p	CLIP-seq
MIRT894092	hsa-miR-4659b-5p	CLIP-seq
MIRT2503858	hsa-miR-466	CLIP-seq
MIRT2503860	hsa-miR-4672	CLIP-seq
MIRT894094	hsa-miR-4731-3p	CLIP-seq
MIRT894095	hsa-miR-4732-5p	CLIP-seq
MIRT894114	hsa-miR-4753-3p	CLIP-seq
MIRT894098	hsa-miR-4776-3p	CLIP-seq
MIRT894099	hsa-miR-4801	CLIP-seq
MIRT894115	hsa-miR-548l	CLIP-seq
MIRT894105	hsa-miR-549	CLIP-seq
MIRT2503876	hsa-miR-624	CLIP-seq
MIRT2201100	hsa-miR-651	CLIP-seq
MIRT894111	hsa-miR-708	CLIP-seq
MIRT894112	hsa-miR-877	CLIP-seq
MIRT894117	hsa-miR-942	CLIP-seq

Gene ontology (GO) Show/Hide all (18)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000281	Process	Mitotic cytokinesis	IGI	16061649
GO:0000922	Component	Spindle pole	IEA
GO:0005730	Component	Nucleolus	IDA
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IDA	21399614
GO:0005819	Component	Spindle	IEA
GO:0005856	Component	Cytoskeleton	IEA
GO:0005874	Component	Microtubule	IEA
GO:0005929	Component	Cilium	IDA
GO:0006915	Process	Apoptotic process	IEA
GO:0007026	Process	Negative regulation of microtubule depolymerization	IBA
GO:0007026	Process	Negative regulation of microtubule depolymerization	IEA
GO:0015630	Component	Microtubule cytoskeleton	IBA
GO:0015630	Component	Microtubule cytoskeleton	IDA	16061649
GO:0015630	Component	Microtubule cytoskeleton	IEA
GO:0036064	Component	Ciliary basal body	IDA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IGI	16061649
GO:0072686	Component	Mitotic spindle	IDA

Other IDs

• MIM: 611569
• HGNC: 1990
• e!Ensembl: ENSG00000136108

Protein

• UniProt ID: Q8WWK9
• Protein name: Cytoskeleton-associated protein 2 (CTCL tumor antigen se20-10) (Tumor- and microtubule-associated protein)
• Protein function: Possesses microtubule stabilizing properties. Involved in regulating aneuploidy, cell cycling, and cell death in a p53/TP53-dependent manner (By similarity).
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF15297	CKAP2_C	325 → 673	Cytoskeleton-associated protein 2 C-terminus	Family

• Tissue specificity: TISSUE SPECIFICITY: Abundant in testis, thymus, and in tumor derived cell lines, while barely detectable in liver, prostate, and kidney. {ECO:0000269|PubMed:9771967}.
• Sequence:

  MSTPAVPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSSRDQRVVT
  SEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHK
  PKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYR
  GQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATT
  KFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSV
  KTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQP
  KETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDEQRLFT
  EKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEPITSPIENI
  IAIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVKEVSIEDTGV
  DVDPEKLEMESKLHRNLLFQDCEKEQDNKTKDPTHDVKTPNTETRTSCLIKYNVSTTPYL
  QSVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCVSSLEQLTELGR
  ETDAFVCRPNAALCRVYYEADTT

• Sequence length: 683

Related Genes

No strongly related genes found yet for CKAP2.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to CKAP2.