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Gene Gene information from NCBI Gene database.
Entrez ID 57019
Gene name Cytokine induced apoptosis inhibitor 1
Gene symbol CIAPIN1
Synonyms (NCBI Gene)
AnamorsinCIAE2DRE2PRO0915
Chromosome 16
Chromosome location 16q21
Summary CIAPIN1 is a cytokine-induced inhibitor of apoptosis with no relation to apoptosis regulatory molecules of the BCL2 (MIM 151430) or CASP (see MIM 147678) families. Expression of CIAPIN1 is dependent on growth factor stimulation (Shibayama et al., 2004 [Pu
miRNA miRNA information provided by mirtarbase database.
454 Show/Hide all (454)
miRTarBase ID miRNA Experiments Reference
MIRT020778 hsa-miR-155-5p Reporter assay;Other 20584899
MIRT041489 hsa-miR-193b-3p CLASH 23622248
MIRT038271 hsa-miR-361-3p CLASH 23622248
MIRT451574 hsa-miR-6847-5p PAR-CLIP 23592263
MIRT451573 hsa-miR-6134 PAR-CLIP 23592263
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
27 Show/Hide all (27)
GO ID Ontology Definition Evidence Reference
GO:0005506 Function Iron ion binding EXP 21700214
GO:0005515 Function Protein binding IPI 16189514, 21516116, 25416956, 26302480, 27519415, 29892012, 31515488, 32296183, 33961781
GO:0005634 Component Nucleus IEA
GO:0005654 Component Nucleoplasm IDA
GO:0005730 Component Nucleolus IDA 16957168
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
608943 28050 ENSG00000005194
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q6FI81
Protein name Anamorsin (Cytokine-induced apoptosis inhibitor 1) (Fe-S cluster assembly protein DRE2 homolog)
Protein function Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilit
PDB 2LD4 , 2YUI , 4M7R
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05093 CIAPIN1 265 → 304 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Family
PF05093 CIAPIN1 230 → 271 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Family
PF08241 Methyltransf_11 2 → 95 Methyltransferase domain Domain
Tissue specificity TISSUE SPECIFICITY: Ubiquitously expressed. Highly expressed in heart, liver and pancreas. {ECO:0000269|PubMed:14970183}.
Sequence
MADFGISAGQFVAVVWDKSSPVEALKGLVDKLQALTGNEGRVSVENIKQLLQSAHKESSF
DIILSGLVPGSTTLHSAEILAEIARILRPGGCLFL
KEPVETAVDNNSKVKTASKLCSALT
LSGLVEVKELQREPLTPEEVQSVREHLGHESDNLLFVQITGKKPNFEVGSSRQLKLSITK
KSSPSVKPAVDPAAAKLWTLSANDMEDDSMDLIDSDELLDPEDLKKPDPASLRAASCGEG
KKRKACKNCTCGLAEELEKEKSRE
QMSSQPKSACGNCYLGDAFRCASCPYLGMPAFKPGE
KVLL
SDSNLHDA
Sequence length 312
Interactions View interactions