CHIC1 (cysteine rich hydrophobic domain 1)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 53344 |
| Gene name | Cysteine rich hydrophobic domain 1 |
| Gene symbol | CHIC1 |
| Synonyms (NCBI Gene) |
BRX
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| Chromosome | X |
| Chromosome location | Xq13.2 |
| Summary | This gene encodes a cysteine-rich hydrophobic (CHIC) domain-containing protein, and is one of the few protein-coding genes found near the X-inactivation center. Studies in mouse indicate that the mouse ortholog of this gene is subject to X-inactivation in |
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miRNA
miRNA information provided by mirtarbase database.
580
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q5VXU3 | ||||||||||
| Protein name | Cysteine-rich hydrophobic domain-containing protein 1 (Brain X-linked protein) | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Equally expressed in various parts of the brain. {ECO:0000269|PubMed:9321471}. | ||||||||||
| Sequence |
MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE |
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| Sequence length | 224 | ||||||||||
| Interactions | View interactions | ||||||||||
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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Related Genes
Genes most often co-reported with CHIC1 across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to CHIC1 (see Related Genes above), that are NOT already directly curated for CHIC1 itself -- a lead worth checking, not a confirmed association.
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