Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	129881
Gene name	Cilia and flagella associated protein 210
Gene symbol	CFAP210
Synonyms (NCBI Gene)	C2orf77CCDC173
Chromosome	2
Chromosome location	2q31.1

16 Show/Hide all (16)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005737	Component	Cytoplasm	IEA
GO:0005856	Component	Cytoskeleton	IEA
GO:0005879	Component	Axonemal microtubule	IBA
GO:0005879	Component	Axonemal microtubule	IDA	36191189
GO:0005879	Component	Axonemal microtubule	ISS
GO:0005929	Component	Cilium	IEA
GO:0005930	Component	Axoneme	IDA	28282151
GO:0030317	Process	Flagellated sperm motility	IEA
GO:0030317	Process	Flagellated sperm motility	ISS
GO:0031514	Component	Motile cilium	IEA
GO:0036126	Component	Sperm flagellum	IEA
GO:0036126	Component	Sperm flagellum	ISS
GO:0042995	Component	Cell projection	IEA
GO:0099513	Component	Polymeric cytoskeletal fiber	IEA
GO:0160112	Component	Axonemal B tubule inner sheath	IEA
GO:0160112	Component	Axonemal B tubule inner sheath	ISS

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Q0VFZ6

Protein name

Cilia- and flagella- associated protein 210 (Coiled-coil domain-containing protein 173)

Protein function

Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.

PDB

7UNG , 8J07

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF13868	TPH	145 → 491	Trichohyalin-plectin-homology domain	Coiled-coil

Tissue specificity

TISSUE SPECIFICITY: Expressed in airway epithelial cells. {ECO:0000269|PubMed:36191189}.

Sequence

MDTSSEMLVRFGRRCGRAKESTEIRNSEEDQVLYLPLLPSKVDLQQVTIIPHDEWKRIQD
SLDRLTREAACLRAERKAKKEMHLRSQEVVKHWTNTYAGMKEQKLEAKKKRDEEIEAERQ
ILDLEEEIYKQGKRKKAIENAKQYQFYQTERVKNFHSGLLLSRVMKERDAQIEFRKSKIK
SDKKWEEQLKLNIEKAFKEEQEKAEKRHRERVALAKDHLKQIKEHEEEEERRKKYEEKDA
EEIKRQNALYEIEMRKKLEKKREEMHESRRRFLEHMQDKHIIKAVEQQQQEEEDEKMRKF
IKAKKRLIQMGKEKEAETHRLMEKRRERIHNFLSELLKEKLDNEDMIIARDIAEAEAEWE
KREREKDEKNKAELKTIAEYRAIVMKNKEEEERQRKIEAKEQLLAVMKADQIFWEHEKEK
KCKADKEHQEVQDAHIQQMAKNKFNAKQAKQAELDYCRLTEALVAEKEKEFQDYAREVIE
LESETTNKYIYPLVKAVQEGPGGGRGPVFVDRGGLRPSYQANDVTGVQLPFYNSQGPKYN
FQKSKRRLGFTW

Sequence length

552

Interactions

View interactions

Related Genes Genes most often co-reported with CFAP210 across shared curated disease and pathway associations. 0 Download as csv Download as pdf
No strongly related genes found yet for CFAP210.

Diseases Linked via Similar Genes Diseases curated for genes most similar to CFAP210 (see Related Genes above), that are NOT already directly curated for CFAP210 itself -- a lead worth checking, not a confirmed association. 0 Download as csv Download as pdf
No additional diseases found yet through genes similar to CFAP210.

CFAP210 (cilia and flagella associated protein 210)

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