Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	286207
Gene name	Cilia and flagella associated protein 157
Gene symbol	CFAP157
Synonyms (NCBI Gene)	C9orf117
Chromosome	9
Chromosome location	9q34.11

15 Show/Hide all (15)

GO ID	Ontology	Definition	Evidence
GO:0005737	Component	Cytoplasm	IEA
GO:0005856	Component	Cytoskeleton	IEA
GO:0005929	Component	Cilium	IEA
GO:0007283	Process	Spermatogenesis	IEA
GO:0007288	Process	Sperm axoneme assembly	IBA
GO:0007288	Process	Sperm axoneme assembly	IEA
GO:0007288	Process	Sperm axoneme assembly	ISS
GO:0008017	Function	Microtubule binding	IBA
GO:0008017	Function	Microtubule binding	IEA
GO:0008017	Function	Microtubule binding	ISS
GO:0030154	Process	Cell differentiation	IEA
GO:0036064	Component	Ciliary basal body	IBA
GO:0036064	Component	Ciliary basal body	IEA
GO:0036064	Component	Ciliary basal body	ISS
GO:0042995	Component	Cell projection	IEA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Q5JU67

Protein name

Cilia- and flagella-associated protein 157

Protein function

Specifically required during spermatogenesis for flagellum morphogenesis and sperm motility. May be required to suppress the formation of supernumerary axonemes and ensure a correct ultrastructure.

Family and domains

Sequence

MAPKKSVSKAGKELEVKKKGGKKEPVVAVEPPLAKEMKEFYHIQIRDLEDRLARYQRKWD
ELAVQEKMFRQEFEQLANNKKEIVAFLKRTLNQQVDEITDLNEQLQNLQLAKEMEKDAFE
AQLAQVRHEFQETKDQLTTENIILGGKLAALEEFRLQKEEVTDKFTLLEEQVRKQENEFR
DYAYNLEKKSVLDKDRLRKEIIQRVNLVANEFHKVTTNRMWETTKRAIKENNGITLQMAR
VSQQGMKLLQENEQLKGRQNNLCKQLELLENTQKVMARHKRGHQKIILMLTKKCQEQQQD
TKEAEELRLLLSQLEQRSLQLQVDNQALKSQRDQLSLQLEQQQVDLQRLQQELANEQKVR
ASLEAALVQATSFLQNILQMHRDEEDSDVDVTFQPWHKEMLQQLLVMLSSTVATRPQKAA
CPHQESQSHGPPKESRPSIQLPRTGSLLPQLSDITPYQPGDLGLVPRQVHIPPNPQDLRL
LSYITRVGTFRAHSSPEMRAPGSLKRLEKFSLPEVPLRPK

Sequence length

520

Interactions

View interactions

Related Genes Genes most often co-reported with CFAP157 across shared curated disease and pathway associations. 0 Download as csv Download as pdf
No strongly related genes found yet for CFAP157.

Diseases Linked via Similar Genes Diseases curated for genes most similar to CFAP157 (see Related Genes above), that are NOT already directly curated for CFAP157 itself -- a lead worth checking, not a confirmed association. 0 Download as csv Download as pdf
No additional diseases found yet through genes similar to CFAP157.

CFAP157 (cilia and flagella associated protein 157)

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