CES4A (carboxylesterase 4A)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 283848
• Gene name: Carboxylesterase 4A
• Gene symbol: CES4A
• Synonyms (NCBI Gene): CES6, CES8
• Chromosome: 16
• Chromosome location: 16q22.1
• Summary: This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bon

miRNA Show/Hide all (36)

miRTarBase ID	miRNA	Experiments	Reference
MIRT715964	hsa-miR-8066	HITS-CLIP	19536157
MIRT715963	hsa-miR-4524b-3p	HITS-CLIP	19536157
MIRT715962	hsa-miR-1324	HITS-CLIP	19536157
MIRT715961	hsa-miR-4269	HITS-CLIP	19536157
MIRT715960	hsa-miR-6715b-5p	HITS-CLIP	19536157
MIRT715959	hsa-miR-1972	HITS-CLIP	19536157
MIRT715958	hsa-miR-4645-5p	HITS-CLIP	19536157
MIRT715957	hsa-miR-4673	HITS-CLIP	19536157
MIRT661415	hsa-miR-6870-3p	HITS-CLIP	23824327
MIRT715964	hsa-miR-8066	HITS-CLIP	19536157
MIRT715963	hsa-miR-4524b-3p	HITS-CLIP	19536157
MIRT715962	hsa-miR-1324	HITS-CLIP	19536157
MIRT715961	hsa-miR-4269	HITS-CLIP	19536157
MIRT715960	hsa-miR-6715b-5p	HITS-CLIP	19536157
MIRT715959	hsa-miR-1972	HITS-CLIP	19536157
MIRT715958	hsa-miR-4645-5p	HITS-CLIP	19536157
MIRT715957	hsa-miR-4673	HITS-CLIP	19536157
MIRT661415	hsa-miR-6870-3p	HITS-CLIP	23824327
MIRT887297	hsa-miR-148a	CLIP-seq
MIRT887298	hsa-miR-148b	CLIP-seq
MIRT887299	hsa-miR-152	CLIP-seq
MIRT887300	hsa-miR-34a	CLIP-seq
MIRT887301	hsa-miR-34c-5p	CLIP-seq
MIRT887302	hsa-miR-3652	CLIP-seq
MIRT887303	hsa-miR-3665	CLIP-seq
MIRT887304	hsa-miR-3978	CLIP-seq
MIRT887305	hsa-miR-4430	CLIP-seq
MIRT887306	hsa-miR-4436b-3p	CLIP-seq
MIRT887307	hsa-miR-449a	CLIP-seq
MIRT887308	hsa-miR-449b	CLIP-seq
MIRT887309	hsa-miR-657	CLIP-seq
MIRT887310	hsa-miR-875-3p	CLIP-seq
MIRT887300	hsa-miR-34a	CLIP-seq
MIRT887301	hsa-miR-34c-5p	CLIP-seq
MIRT887307	hsa-miR-449a	CLIP-seq
MIRT887308	hsa-miR-449b	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005576	Component	Extracellular region	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0052689	Function	Carboxylic ester hydrolase activity	IEA

Other IDs

• MIM: 621153
• HGNC: 26741
• e!Ensembl: ENSG00000172824

Protein

• UniProt ID: Q5XG92
• Protein name: Carboxylesterase 4A (EC 3.1.1.-)
• Protein function: Probable carboxylesterase.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00135	COesterase	25 → 546	Carboxylesterase family	Domain

• Sequence:

  MRWILCWSLTLCLMAQTALGALHTKRPQVVTKYGTLQGKQMHVGKTPIQVFLGVPFSRPP
  LGILRFAPPEPPEPWKGIRDATTYPPGCLQESWGQLASMYVSTRERYKWLRFSEDCLYLN
  VYAPARAPGDPQLPVMVWFPGGAFIVGAASSYEGSDLAAREKVVLVFLQHRLGIFGFLST
  DDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLF
  HRAISQSGTALFRLFITSNPLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKM
  RFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLPY
  IMKFPLNRQAMRKETITKMLWSTRTLLNITKEQVPLVVEEYLDNVNEHDWKMLRNRMMDI
  VQDATFVYATLQTAHYHRDAGLPVYLYEFEHHARGIIVKPRTDGADHGDEMYFLFGGPFA
  TGLSMGKEKALSLQMMKYWANFARTGNPNDGNLPCWPRYNKDEKYLQLDFTTRVGMKLKE
  KKMAFWMSLYQSQRPEKQRQF

• Sequence length: 561

Related Genes

No strongly related genes found yet for CES4A.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to CES4A.