CEACAM7 (CEA cell adhesion molecule 7)

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Gene miRNA Gene ontology Other IDs Protein Pathways Diseases linked via similar genes

Gene

• Entrez ID: 1087
• Gene name: CEA cell adhesion molecule 7
• Gene symbol: CEACAM7
• Synonyms (NCBI Gene): CGM2
• Chromosome: 19
• Chromosome location: 19q13.2
• Summary: This gene encodes a cell surface glycoprotein and member of the carcinoembryonic antigen (CEA) family of proteins. Expression of this gene may be downregulated in colon and rectal cancer. Additionally, lower expression levels of this gene may be predictiv

miRNA Show/Hide all (79)

miRTarBase ID	miRNA	Experiments	Reference
MIRT883079	hsa-miR-1245	CLIP-seq
MIRT883080	hsa-miR-2276	CLIP-seq
MIRT883081	hsa-miR-2682	CLIP-seq
MIRT883082	hsa-miR-3064-3p	CLIP-seq
MIRT883083	hsa-miR-3120-3p	CLIP-seq
MIRT883084	hsa-miR-3127-5p	CLIP-seq
MIRT883085	hsa-miR-3136-3p	CLIP-seq
MIRT883086	hsa-miR-325	CLIP-seq
MIRT883087	hsa-miR-345	CLIP-seq
MIRT883088	hsa-miR-3606	CLIP-seq
MIRT883089	hsa-miR-3646	CLIP-seq
MIRT883090	hsa-miR-3662	CLIP-seq
MIRT883091	hsa-miR-3677-5p	CLIP-seq
MIRT883092	hsa-miR-3918	CLIP-seq
MIRT883093	hsa-miR-3921	CLIP-seq
MIRT883094	hsa-miR-4263	CLIP-seq
MIRT883095	hsa-miR-4310	CLIP-seq
MIRT883096	hsa-miR-4318	CLIP-seq
MIRT883097	hsa-miR-4422	CLIP-seq
MIRT883098	hsa-miR-4424	CLIP-seq
MIRT883099	hsa-miR-4436b-3p	CLIP-seq
MIRT883100	hsa-miR-4481	CLIP-seq
MIRT883101	hsa-miR-449c	CLIP-seq
MIRT883102	hsa-miR-4652-3p	CLIP-seq
MIRT883103	hsa-miR-4653-5p	CLIP-seq
MIRT883104	hsa-miR-4682	CLIP-seq
MIRT883105	hsa-miR-4693-3p	CLIP-seq
MIRT883106	hsa-miR-4693-5p	CLIP-seq
MIRT883107	hsa-miR-4712-3p	CLIP-seq
MIRT883108	hsa-miR-4745-5p	CLIP-seq
MIRT883109	hsa-miR-4758-5p	CLIP-seq
MIRT883110	hsa-miR-4768-3p	CLIP-seq
MIRT883111	hsa-miR-4772-3p	CLIP-seq
MIRT883112	hsa-miR-4778-5p	CLIP-seq
MIRT883113	hsa-miR-544	CLIP-seq
MIRT883114	hsa-miR-550b	CLIP-seq
MIRT883115	hsa-miR-576-5p	CLIP-seq
MIRT883116	hsa-miR-587	CLIP-seq
MIRT883117	hsa-miR-628-5p	CLIP-seq
MIRT883118	hsa-miR-629	CLIP-seq
MIRT883119	hsa-miR-659	CLIP-seq
MIRT883120	hsa-miR-663b	CLIP-seq
MIRT883121	hsa-miR-892a	CLIP-seq
MIRT883122	hsa-miR-921	CLIP-seq
MIRT883123	hsa-miR-940	CLIP-seq
MIRT1961866	hsa-miR-203	CLIP-seq
MIRT1961867	hsa-miR-502-5p	CLIP-seq
MIRT2198404	hsa-miR-1269	CLIP-seq
MIRT2198405	hsa-miR-1269b	CLIP-seq
MIRT2198406	hsa-miR-1272	CLIP-seq
MIRT2198407	hsa-miR-1322	CLIP-seq
MIRT2198408	hsa-miR-141	CLIP-seq
MIRT2198409	hsa-miR-182	CLIP-seq
MIRT2198410	hsa-miR-200a	CLIP-seq
MIRT2198411	hsa-miR-223	CLIP-seq
MIRT2198412	hsa-miR-2355-3p	CLIP-seq
MIRT883081	hsa-miR-2682	CLIP-seq
MIRT2198413	hsa-miR-2964a-5p	CLIP-seq
MIRT883089	hsa-miR-3646	CLIP-seq
MIRT2198414	hsa-miR-3655	CLIP-seq
MIRT2198415	hsa-miR-3909	CLIP-seq
MIRT883101	hsa-miR-449c	CLIP-seq
MIRT2198416	hsa-miR-4520b-3p	CLIP-seq
MIRT2198417	hsa-miR-4529-3p	CLIP-seq
MIRT883105	hsa-miR-4693-3p	CLIP-seq
MIRT2198418	hsa-miR-4697-3p	CLIP-seq
MIRT883107	hsa-miR-4712-3p	CLIP-seq
MIRT2198419	hsa-miR-487a	CLIP-seq
MIRT2198420	hsa-miR-578	CLIP-seq
MIRT2198421	hsa-miR-617	CLIP-seq
MIRT2198422	hsa-miR-676	CLIP-seq
MIRT2198423	hsa-miR-935	CLIP-seq
MIRT883123	hsa-miR-940	CLIP-seq
MIRT2198408	hsa-miR-141	CLIP-seq
MIRT2198410	hsa-miR-200a	CLIP-seq
MIRT2385905	hsa-miR-2053	CLIP-seq
MIRT2198411	hsa-miR-223	CLIP-seq
MIRT2198418	hsa-miR-4697-3p	CLIP-seq
MIRT2198423	hsa-miR-935	CLIP-seq

Gene ontology (GO) Show/Hide all (14)

GO ID	Ontology	Definition	Evidence	Reference
GO:0002682	Process	Regulation of immune system process	IBA
GO:0005576	Component	Extracellular region	TAS
GO:0005829	Component	Cytosol	IDA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IDA
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0007165	Process	Signal transduction	IBA
GO:0009986	Component	Cell surface	IBA
GO:0016020	Component	Membrane	IEA
GO:0016324	Component	Apical plasma membrane	IDA	10436421
GO:0016324	Component	Apical plasma membrane	IEA
GO:0098552	Component	Side of membrane	IEA
GO:1990782	Function	Protein tyrosine kinase binding	IBA

Other IDs

• MIM: 619160
• HGNC: 1819
• e!Ensembl: ENSG00000007306

Protein

• UniProt ID: Q14002
• Protein name: Cell adhesion molecule CEACAM7 (Carcinoembryonic antigen CGM2) (Carcinoembryonic antigen-related cell adhesion molecule 7) (CEA cell adhesion molecule 7)
• PDB: 4Y89
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF07686	V-set	41 → 142	Immunoglobulin V-set domain	Domain
  PF13927	Ig_3	147 → 220		Domain

• Tissue specificity: TISSUE SPECIFICITY: Expressed in columnar epithelial cells of the colon (at protein level) (PubMed:10436421). Strongly down-regulated in colonic adenocarcinomas. {ECO:0000269|PubMed:10436421}.
• Sequence:

  MGSPSACPYRVCIPWQGLLLTASLLTFWNLPNSAQTNIDVVPFNVAEGKEVLLVVHNESQ
  NLYGYNWYKGERVHANYRIIGYVKNISQENAPGPAHNGRETIYPNGTLLIQNVTHNDAGF
  YTLHVIKENLVNEEVTRQFYVFSEPPKPSITSNNFNPVENKDIVVLTCQPETQNTTYLWW
  VNNQSLLVSPRLLLSTDNRTLVLLSATKNDIGPYECEIQNPVGASRSDPVTLNVRYESVQ
  ASSPDLSAGTAVSIMIGVLAGMALI

• Sequence length: 265

Pathways

Reactome Pathway:

Post-translational modification: synthesis of GPI-anchored proteins

Related Genes

No strongly related genes found yet for CEACAM7.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to CEACAM7.