CDC42EP4 (CDC42 effector protein 4)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 23580 |
| Gene name | CDC42 effector protein 4 |
| Gene symbol | CDC42EP4 |
| Synonyms (NCBI Gene) |
BORG4CEP4KAIA1777
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| Chromosome | 17 |
| Chromosome location | 17q25.1 |
| Summary | The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9H3Q1 | |||||||||||||||
| Protein name | Cdc42 effector protein 4 (Binder of Rho GTPases 4) | |||||||||||||||
| Protein function | Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation, when overexpressed in fibroblasts. | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Not detected in any of the adult tissues tested. May be expressed only in fetal or embryonic tissues. | |||||||||||||||
| Sequence |
MPILKQLVSSSVHSKRRSRADLTAEMISAPLGDFRHTMHVGRAGDAFGDTSFLNSKAGEP |
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| Sequence length | 356 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Related Genes
Genes most often co-reported with CDC42EP4 across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to CDC42EP4 (see Related Genes above), that are NOT already directly curated for CDC42EP4 itself -- a lead worth checking, not a confirmed association.
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