CCNI (cyclin I)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 10983
• Gene name: Cyclin I
• Gene symbol: CCNI
• Synonyms (NCBI Gene): CCNI1, CYC1, CYI
• Chromosome: 4
• Chromosome location: 4q21.1
• Summary: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit

miRNA Show/Hide all (90)

miRTarBase ID	miRNA	Experiments	Reference
MIRT016039	hsa-miR-374b-5p	Sequencing	20371350
MIRT028976	hsa-miR-26b-5p	Microarray	19088304
MIRT049008	hsa-miR-92a-3p	CLASH	23622248
MIRT048043	hsa-miR-148a-3p	CLASH	23622248
MIRT044457	hsa-miR-320a	CLASH	23622248
MIRT038027	hsa-miR-423-5p	CLASH	23622248
MIRT641672	hsa-miR-455-5p	HITS-CLIP	23824327
MIRT641671	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT641670	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT641669	hsa-miR-133a-3p	HITS-CLIP	23824327
MIRT641668	hsa-miR-133b	HITS-CLIP	23824327
MIRT641667	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT641672	hsa-miR-455-5p	HITS-CLIP	23824327
MIRT641671	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT641670	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT641669	hsa-miR-133a-3p	HITS-CLIP	23824327
MIRT641668	hsa-miR-133b	HITS-CLIP	23824327
MIRT641667	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT872222	hsa-miR-1200	CLIP-seq
MIRT872223	hsa-miR-1237	CLIP-seq
MIRT872224	hsa-miR-1248	CLIP-seq
MIRT872225	hsa-miR-139-5p	CLIP-seq
MIRT872226	hsa-miR-149	CLIP-seq
MIRT872227	hsa-miR-218	CLIP-seq
MIRT872228	hsa-miR-24	CLIP-seq
MIRT872229	hsa-miR-3064-5p	CLIP-seq
MIRT872230	hsa-miR-3074-5p	CLIP-seq
MIRT872231	hsa-miR-3124-3p	CLIP-seq
MIRT872232	hsa-miR-3145-5p	CLIP-seq
MIRT872233	hsa-miR-374a	CLIP-seq
MIRT872234	hsa-miR-374b	CLIP-seq
MIRT872235	hsa-miR-4284	CLIP-seq
MIRT872236	hsa-miR-450b-5p	CLIP-seq
MIRT872237	hsa-miR-4662a-5p	CLIP-seq
MIRT872238	hsa-miR-4680-3p	CLIP-seq
MIRT872239	hsa-miR-4693-3p	CLIP-seq
MIRT872240	hsa-miR-4712-3p	CLIP-seq
MIRT872241	hsa-miR-4719	CLIP-seq
MIRT872242	hsa-miR-4720-3p	CLIP-seq
MIRT872243	hsa-miR-4794	CLIP-seq
MIRT872244	hsa-miR-4804-3p	CLIP-seq
MIRT872245	hsa-miR-483-3p	CLIP-seq
MIRT872246	hsa-miR-507	CLIP-seq
MIRT872247	hsa-miR-548ag	CLIP-seq
MIRT872248	hsa-miR-548ai	CLIP-seq
MIRT872249	hsa-miR-557	CLIP-seq
MIRT872250	hsa-miR-636	CLIP-seq
MIRT872222	hsa-miR-1200	CLIP-seq
MIRT872223	hsa-miR-1237	CLIP-seq
MIRT872224	hsa-miR-1248	CLIP-seq
MIRT872225	hsa-miR-139-5p	CLIP-seq
MIRT1958874	hsa-miR-2117	CLIP-seq
MIRT872230	hsa-miR-3074-5p	CLIP-seq
MIRT872231	hsa-miR-3124-3p	CLIP-seq
MIRT1958875	hsa-miR-3973	CLIP-seq
MIRT1958876	hsa-miR-4273	CLIP-seq
MIRT872236	hsa-miR-450b-5p	CLIP-seq
MIRT872246	hsa-miR-507	CLIP-seq
MIRT872247	hsa-miR-548ag	CLIP-seq
MIRT872248	hsa-miR-548ai	CLIP-seq
MIRT872249	hsa-miR-557	CLIP-seq
MIRT872222	hsa-miR-1200	CLIP-seq
MIRT872223	hsa-miR-1237	CLIP-seq
MIRT872224	hsa-miR-1248	CLIP-seq
MIRT872225	hsa-miR-139-5p	CLIP-seq
MIRT872226	hsa-miR-149	CLIP-seq
MIRT1958874	hsa-miR-2117	CLIP-seq
MIRT872228	hsa-miR-24	CLIP-seq
MIRT872229	hsa-miR-3064-5p	CLIP-seq
MIRT872230	hsa-miR-3074-5p	CLIP-seq
MIRT872231	hsa-miR-3124-3p	CLIP-seq
MIRT872232	hsa-miR-3145-5p	CLIP-seq
MIRT872233	hsa-miR-374a	CLIP-seq
MIRT872234	hsa-miR-374b	CLIP-seq
MIRT1958875	hsa-miR-3973	CLIP-seq
MIRT1958876	hsa-miR-4273	CLIP-seq
MIRT872235	hsa-miR-4284	CLIP-seq
MIRT872236	hsa-miR-450b-5p	CLIP-seq
MIRT872237	hsa-miR-4662a-5p	CLIP-seq
MIRT872238	hsa-miR-4680-3p	CLIP-seq
MIRT872239	hsa-miR-4693-3p	CLIP-seq
MIRT872240	hsa-miR-4712-3p	CLIP-seq
MIRT872241	hsa-miR-4719	CLIP-seq
MIRT872243	hsa-miR-4794	CLIP-seq
MIRT872245	hsa-miR-483-3p	CLIP-seq
MIRT872246	hsa-miR-507	CLIP-seq
MIRT872247	hsa-miR-548ag	CLIP-seq
MIRT872248	hsa-miR-548ai	CLIP-seq
MIRT872249	hsa-miR-557	CLIP-seq
MIRT2195735	hsa-miR-888	CLIP-seq

Gene ontology (GO) Show/Hide all (10)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000082	Process	G1/S transition of mitotic cell cycle	IBA
GO:0000307	Component	Cyclin-dependent protein kinase holoenzyme complex	IBA
GO:0005515	Function	Protein binding	IPI	25852190, 32296183, 33961781
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0007283	Process	Spermatogenesis	NAS	9705831
GO:0016020	Component	Membrane	IEA
GO:0016538	Function	Cyclin-dependent protein serine/threonine kinase regulator activity	IBA
GO:0031965	Component	Nuclear membrane	IEA

Other IDs

• MIM: 618783
• HGNC: 1595
• e!Ensembl: ENSG00000118816

Protein

• UniProt ID: Q14094
• Protein name: Cyclin-I
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00134	Cyclin_N	15 → 143	Cyclin, N-terminal domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Highest levels in adult heart, brain and skeletal muscle. Lower levels in adult placenta, lung, kidney and pancreas. Also high levels in fetal brain and lower levels in fetal lung, liver and kidney. Also abundant in testis and thyroid.
• Sequence:

  MKFPGPLENQRLSFLLEKAITREAQMWKVNVRKMPSNQNVSPSQRDEVIQWLAKLKYQFN
  LYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFLAAKTVEEDERIPVLKVLARDSFC
  GCSSSEILRMERIILDKLNWDLHTATPLDFLHIFHAIAVSTRPQLLFSLPKLSPSQHLAV
  LTKQLLHCMACNQLLQFRGSMLALAMVSLEMEKLIPDWLSLTIELLQKAQMDSSQLIHCR
  ELVAHHLSTLQSSLPLNSVYVYRPLKHTLVTCDKGVFRLHPSSVPGPDFSKDNSKPEVPV
  RGTAAFYHHLPAASGCKQTSTKRKVEEMEVDDFYDGIKRLYNEDNVSENVGSVCGTDLSR
  QEGHASPCPPLQPVSVM

• Sequence length: 377

Related Genes

No strongly related genes found yet for CCNI.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to CCNI.