CCDC124 (coiled-coil domain containing 124)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 115098
• Gene name: Coiled-coil domain containing 124
• Gene symbol: CCDC124
• Synonyms (NCBI Gene): Lso2, oxs1
• Chromosome: 19
• Chromosome location: 19p13.11

miRNA Show/Hide all (66)

miRTarBase ID	miRNA	Experiments	Reference
MIRT023621	hsa-miR-1-3p	Proteomics;Microarray	18668037
MIRT045956	hsa-miR-125b-5p	CLASH	23622248
MIRT867854	hsa-miR-138	CLIP-seq
MIRT867855	hsa-miR-1908	CLIP-seq
MIRT867856	hsa-miR-3195	CLIP-seq
MIRT867857	hsa-miR-328	CLIP-seq
MIRT867858	hsa-miR-329	CLIP-seq
MIRT867859	hsa-miR-342-5p	CLIP-seq
MIRT867860	hsa-miR-362-3p	CLIP-seq
MIRT867861	hsa-miR-3652	CLIP-seq
MIRT867862	hsa-miR-3689a-3p	CLIP-seq
MIRT867863	hsa-miR-3689c	CLIP-seq
MIRT867864	hsa-miR-3941	CLIP-seq
MIRT867865	hsa-miR-4299	CLIP-seq
MIRT867866	hsa-miR-4430	CLIP-seq
MIRT867867	hsa-miR-4505	CLIP-seq
MIRT867868	hsa-miR-4525	CLIP-seq
MIRT867869	hsa-miR-4651	CLIP-seq
MIRT867870	hsa-miR-4664-5p	CLIP-seq
MIRT867871	hsa-miR-4728-5p	CLIP-seq
MIRT867872	hsa-miR-566	CLIP-seq
MIRT867873	hsa-miR-597	CLIP-seq
MIRT867874	hsa-miR-603	CLIP-seq
MIRT867875	hsa-miR-608	CLIP-seq
MIRT867876	hsa-miR-663	CLIP-seq
MIRT867877	hsa-miR-668	CLIP-seq
MIRT2436102	hsa-miR-125a-5p	CLIP-seq
MIRT2436103	hsa-miR-125b	CLIP-seq
MIRT2436104	hsa-miR-2467-5p	CLIP-seq
MIRT2436105	hsa-miR-3188	CLIP-seq
MIRT867858	hsa-miR-329	CLIP-seq
MIRT867860	hsa-miR-362-3p	CLIP-seq
MIRT867864	hsa-miR-3941	CLIP-seq
MIRT2436106	hsa-miR-3975	CLIP-seq
MIRT2436107	hsa-miR-4319	CLIP-seq
MIRT2436108	hsa-miR-4649-3p	CLIP-seq
MIRT2436109	hsa-miR-4690-3p	CLIP-seq
MIRT2436110	hsa-miR-485-5p	CLIP-seq
MIRT2436111	hsa-miR-512-5p	CLIP-seq
MIRT2436112	hsa-miR-544b	CLIP-seq
MIRT867874	hsa-miR-603	CLIP-seq
MIRT2436102	hsa-miR-125a-5p	CLIP-seq
MIRT2436103	hsa-miR-125b	CLIP-seq
MIRT2436104	hsa-miR-2467-5p	CLIP-seq
MIRT2436105	hsa-miR-3188	CLIP-seq
MIRT867858	hsa-miR-329	CLIP-seq
MIRT867860	hsa-miR-362-3p	CLIP-seq
MIRT867864	hsa-miR-3941	CLIP-seq
MIRT2436106	hsa-miR-3975	CLIP-seq
MIRT2436107	hsa-miR-4319	CLIP-seq
MIRT2436108	hsa-miR-4649-3p	CLIP-seq
MIRT2436109	hsa-miR-4690-3p	CLIP-seq
MIRT2436110	hsa-miR-485-5p	CLIP-seq
MIRT2436111	hsa-miR-512-5p	CLIP-seq
MIRT2436112	hsa-miR-544b	CLIP-seq
MIRT867874	hsa-miR-603	CLIP-seq
MIRT2497827	hsa-miR-1268	CLIP-seq
MIRT2497828	hsa-miR-1268b	CLIP-seq
MIRT2497829	hsa-miR-2467-3p	CLIP-seq
MIRT2497830	hsa-miR-3176	CLIP-seq
MIRT2497831	hsa-miR-3661	CLIP-seq
MIRT2497832	hsa-miR-3678-3p	CLIP-seq
MIRT2497833	hsa-miR-3922-3p	CLIP-seq
MIRT2497834	hsa-miR-4725-5p	CLIP-seq
MIRT2497835	hsa-miR-504	CLIP-seq
MIRT2497836	hsa-miR-631	CLIP-seq

Gene ontology (GO) Show/Hide all (13)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003713	Function	Transcription coactivator activity	IBA
GO:0003723	Function	RNA binding	HDA	22658674
GO:0005515	Function	Protein binding	IPI	35271311, 38029384
GO:0005634	Component	Nucleus	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005856	Component	Cytoskeleton	IEA
GO:0005886	Component	Plasma membrane	IDA
GO:0006366	Process	Transcription by RNA polymerase II	IBA
GO:0030496	Component	Midbody	IEA
GO:0045893	Process	Positive regulation of DNA-templated transcription	IEA
GO:0051301	Process	Cell division	IEA

Other IDs

• MIM: 621286
• HGNC: 25171
• e!Ensembl: ENSG00000007080

Protein

• UniProt ID: Q96CT7
• Protein name: Coiled-coil domain-containing protein 124
• Protein function: Ribosome-binding protein involved in ribosome hibernation: associates with translationally inactive ribosomes and stabilizes the nonrotated conformation of the 80S ribosome, thereby promoting ribosome preservation and storage (PubMed:32687489).
• PDB: 6Z6L , 6ZM7 , 6ZME , 8K2C , 8XSY
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF06244	Ccdc124	8 → 214	Coiled-coil domain-containing protein 124 /Oxs1	Family

• Tissue specificity: TISSUE SPECIFICITY: Ubiquitously expressed. {ECO:0000269|PubMed:23894443}.
• Sequence:

  MPKKFQGENTKSAAARARRAEAKAAADAKKQKELEDAYWKDDDKHVMRKEQRKEEKEKRR
  LDQLERKKETQRLLEEEDSKLKGGKAPRVATSSKVTRAQIEDTLRRDHQLREAPDTAEKA
  KSHLEVPLEENVNRRVLEEGSVEARTIEDAIAVLSVAEEAADRHPERRMRAAFTAFEEAQ
  LPRLKQENPNMRLSQLKQLLKKEWLRSPDNPMNQRAVPFNAPK

• Sequence length: 223

Related Genes

No strongly related genes found yet for CCDC124.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to CCDC124.