CASKIN2 (CASK interacting protein 2)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 57513
• Gene name: CASK interacting protein 2
• Gene symbol: CASKIN2
• Synonyms (NCBI Gene): ANKS5B
• Chromosome: 17
• Chromosome location: 17q25.1
• Summary: This gene encodes a large protein that contains six ankyrin repeats, as well as a Src homology 3 (SH3) domain and two sterile alpha motif (SAM) domains, which may be involved in protein-protein interactions. The C-terminal portion of this protein is proli

miRNA Show/Hide all (128)

miRTarBase ID	miRNA	Experiments	Reference
MIRT018329	hsa-miR-335-5p	Microarray	18185580
MIRT046713	hsa-miR-222-3p	CLASH	23622248
MIRT863565	hsa-miR-1193	CLIP-seq
MIRT863566	hsa-miR-1266	CLIP-seq
MIRT863567	hsa-miR-1281	CLIP-seq
MIRT863568	hsa-miR-1285	CLIP-seq
MIRT863569	hsa-miR-1538	CLIP-seq
MIRT863570	hsa-miR-1587	CLIP-seq
MIRT863571	hsa-miR-18a	CLIP-seq
MIRT863572	hsa-miR-18b	CLIP-seq
MIRT863573	hsa-miR-1913	CLIP-seq
MIRT863574	hsa-miR-3187-5p	CLIP-seq
MIRT863575	hsa-miR-3189-5p	CLIP-seq
MIRT863576	hsa-miR-324-3p	CLIP-seq
MIRT863577	hsa-miR-335	CLIP-seq
MIRT863578	hsa-miR-3648	CLIP-seq
MIRT863579	hsa-miR-4263	CLIP-seq
MIRT863580	hsa-miR-4417	CLIP-seq
MIRT863581	hsa-miR-4492	CLIP-seq
MIRT863582	hsa-miR-4498	CLIP-seq
MIRT863583	hsa-miR-4521	CLIP-seq
MIRT863584	hsa-miR-4655-3p	CLIP-seq
MIRT863585	hsa-miR-4656	CLIP-seq
MIRT863586	hsa-miR-4675	CLIP-seq
MIRT863587	hsa-miR-4691-5p	CLIP-seq
MIRT863588	hsa-miR-4735-3p	CLIP-seq
MIRT863589	hsa-miR-4741	CLIP-seq
MIRT863590	hsa-miR-4745-3p	CLIP-seq
MIRT863591	hsa-miR-4758-3p	CLIP-seq
MIRT863592	hsa-miR-541	CLIP-seq
MIRT863593	hsa-miR-612	CLIP-seq
MIRT863594	hsa-miR-661	CLIP-seq
MIRT863595	hsa-miR-762	CLIP-seq
MIRT863596	hsa-miR-766	CLIP-seq
MIRT863565	hsa-miR-1193	CLIP-seq
MIRT863597	hsa-miR-1275	CLIP-seq
MIRT863568	hsa-miR-1285	CLIP-seq
MIRT863598	hsa-miR-1291	CLIP-seq
MIRT863599	hsa-miR-129-3p	CLIP-seq
MIRT863569	hsa-miR-1538	CLIP-seq
MIRT863570	hsa-miR-1587	CLIP-seq
MIRT863571	hsa-miR-18a	CLIP-seq
MIRT863572	hsa-miR-18b	CLIP-seq
MIRT863573	hsa-miR-1913	CLIP-seq
MIRT863600	hsa-miR-31	CLIP-seq
MIRT863601	hsa-miR-3157-5p	CLIP-seq
MIRT863602	hsa-miR-3173-5p	CLIP-seq
MIRT863603	hsa-miR-3179	CLIP-seq
MIRT863604	hsa-miR-3184	CLIP-seq
MIRT863574	hsa-miR-3187-5p	CLIP-seq
MIRT863575	hsa-miR-3189-5p	CLIP-seq
MIRT863605	hsa-miR-3202	CLIP-seq
MIRT863576	hsa-miR-324-3p	CLIP-seq
MIRT863606	hsa-miR-328	CLIP-seq
MIRT863577	hsa-miR-335	CLIP-seq
MIRT863578	hsa-miR-3648	CLIP-seq
MIRT863607	hsa-miR-409-5p	CLIP-seq
MIRT863608	hsa-miR-423-5p	CLIP-seq
MIRT863609	hsa-miR-4259	CLIP-seq
MIRT863579	hsa-miR-4263	CLIP-seq
MIRT863610	hsa-miR-4266	CLIP-seq
MIRT863611	hsa-miR-4271	CLIP-seq
MIRT863612	hsa-miR-4293	CLIP-seq
MIRT863580	hsa-miR-4417	CLIP-seq
MIRT863613	hsa-miR-4481	CLIP-seq
MIRT863581	hsa-miR-4492	CLIP-seq
MIRT863582	hsa-miR-4498	CLIP-seq
MIRT863583	hsa-miR-4521	CLIP-seq
MIRT863614	hsa-miR-4525	CLIP-seq
MIRT863585	hsa-miR-4656	CLIP-seq
MIRT863615	hsa-miR-4665-5p	CLIP-seq
MIRT863586	hsa-miR-4675	CLIP-seq
MIRT863616	hsa-miR-4688	CLIP-seq
MIRT863617	hsa-miR-4695-5p	CLIP-seq
MIRT863618	hsa-miR-4715-5p	CLIP-seq
MIRT863619	hsa-miR-4723-5p	CLIP-seq
MIRT863620	hsa-miR-4725-3p	CLIP-seq
MIRT863588	hsa-miR-4735-3p	CLIP-seq
MIRT863589	hsa-miR-4741	CLIP-seq
MIRT863590	hsa-miR-4745-3p	CLIP-seq
MIRT863621	hsa-miR-4745-5p	CLIP-seq
MIRT863622	hsa-miR-4747-5p	CLIP-seq
MIRT863591	hsa-miR-4758-3p	CLIP-seq
MIRT863623	hsa-miR-4758-5p	CLIP-seq
MIRT863624	hsa-miR-4779	CLIP-seq
MIRT863625	hsa-miR-4797-5p	CLIP-seq
MIRT863592	hsa-miR-541	CLIP-seq
MIRT863626	hsa-miR-569	CLIP-seq
MIRT863593	hsa-miR-612	CLIP-seq
MIRT863627	hsa-miR-625	CLIP-seq
MIRT863594	hsa-miR-661	CLIP-seq
MIRT863595	hsa-miR-762	CLIP-seq
MIRT863566	hsa-miR-1266	CLIP-seq
MIRT1956056	hsa-miR-4671-5p	CLIP-seq
MIRT863566	hsa-miR-1266	CLIP-seq
MIRT1956057	hsa-miR-2682	CLIP-seq
MIRT1956058	hsa-miR-449c	CLIP-seq
MIRT2193663	hsa-miR-1254	CLIP-seq
MIRT863568	hsa-miR-1285	CLIP-seq
MIRT863570	hsa-miR-1587	CLIP-seq
MIRT863571	hsa-miR-18a	CLIP-seq
MIRT863572	hsa-miR-18b	CLIP-seq
MIRT863573	hsa-miR-1913	CLIP-seq
MIRT2193664	hsa-miR-22	CLIP-seq
MIRT2193665	hsa-miR-28-5p	CLIP-seq
MIRT2193666	hsa-miR-3116	CLIP-seq
MIRT2193667	hsa-miR-3139	CLIP-seq
MIRT863574	hsa-miR-3187-5p	CLIP-seq
MIRT863575	hsa-miR-3189-5p	CLIP-seq
MIRT863576	hsa-miR-324-3p	CLIP-seq
MIRT863577	hsa-miR-335	CLIP-seq
MIRT863579	hsa-miR-4263	CLIP-seq
MIRT863580	hsa-miR-4417	CLIP-seq
MIRT863581	hsa-miR-4492	CLIP-seq
MIRT863582	hsa-miR-4498	CLIP-seq
MIRT863583	hsa-miR-4521	CLIP-seq
MIRT863585	hsa-miR-4656	CLIP-seq
MIRT863586	hsa-miR-4675	CLIP-seq
MIRT2193668	hsa-miR-4722-5p	CLIP-seq
MIRT863588	hsa-miR-4735-3p	CLIP-seq
MIRT863589	hsa-miR-4741	CLIP-seq
MIRT863591	hsa-miR-4758-3p	CLIP-seq
MIRT863592	hsa-miR-541	CLIP-seq
MIRT2193669	hsa-miR-558	CLIP-seq
MIRT863593	hsa-miR-612	CLIP-seq
MIRT863594	hsa-miR-661	CLIP-seq
MIRT2193670	hsa-miR-708	CLIP-seq
MIRT863595	hsa-miR-762	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	ISS	12040031

Other IDs

• MIM: 612185
• HGNC: 18200
• e!Ensembl: ENSG00000177303

Protein

• UniProt ID: Q8WXE0
• Protein name: Caskin-2 (CASK-interacting protein 2)
• PDB: 2KE9 , 4IS7 , 5L1M , 7ZW4
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00536	SAM_1	556 → 620	SAM domain (Sterile alpha motif)	Domain
  PF00536	SAM_1	487 → 550	SAM domain (Sterile alpha motif)	Domain
  PF07653	SH3_2	285 → 345	Variant SH3 domain	Domain
  PF12796	Ank_2	169 → 251	Ankyrin repeats (3 copies)	Repeat
  PF12796	Ank_2	7 → 112	Ankyrin repeats (3 copies)	Repeat
  PF12796	Ank_2	98 → 175	Ankyrin repeats (3 copies)	Repeat
  PF13857	Ank_5	208 → 261		Repeat
  PF16600	Caskin1-CID	393 → 457	Caskin1 CASK-interaction domain	Family
  PF16632	Caskin-tail	1145 → 1202	C-terminal region of Caskin	Disordered
  PF16907	Caskin-Pro-rich	794 → 886		Family

• Sequence:

  MGREQDLILAVKNGDVTGVQKLVAKVKATKTKLLGSTKRLNVNYQDADGFSALHHAALGG
  SLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLH
  LAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGE
  AKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTGTALHEAALYGKTEVVRLL
  LEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREASGILKVRALKDFWNLHDPTA
  LNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRIGYFPPGIVEVVSKRVGIPAARLPSAP
  TPLRPGFSRTPQPPAEEPPHPLTYSQLPRVGLSPDSPAGDRNSVGSEGSVGSIRSAGSGQ
  SSEGTNGHGPGLLIENAQPLPSAGEDQVLPGLHPPSLADNLSHRPLANCRSGEQIFTQDV
  RPEQLLEGKDAQAIHNWLSEFQLEGYTAHFLQAGYDVPTISRMTPEDLTAIGVTKPGHRK
  KIASEIAQLSIAEWLPSYIPTDLLEWLCALGLPQYHKQLVSSGYDSMGLVADLTWEELQE
  IGVNKLGHQKKLMLGVKRLAELRRGLLQGEALSEGGRRLAKGPELMAIEGLENGEGPATA
  GPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQPAPQPS
  GGDPSPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSY
  LAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVR
  TSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGAT
  GPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTI
  KQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPAA
  PLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLESSAASRWN
  GETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAPRLGPRPVPPPRPESTGTVG
  PGQAQQRLEQTSSSLAAALRAAEKSIGTKEQEGTPSASTKHILDDISTMFDALADQLDAM
  LD

• Sequence length: 1202

Related Genes

No strongly related genes found yet for CASKIN2.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to CASKIN2.