CASC21 (cancer susceptibility 21)

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Gene Other IDs Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 103021164
• Gene name: Cancer susceptibility 21
• Gene symbol: CASC21
• Synonyms (NCBI Gene): CARLO2, CARLo-2, LINC01244
• Chromosome: 8
• Chromosome location: 8q24.21

Other IDs

• MIM: 617702
• HGNC: 49836
• e!Ensembl: HGNC

Interactions View interactions

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
Familial prostate cancer	association	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining Show/Hide Text Mining Associations (15)
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Breast Neoplasms	Breast neoplasm	Pubtator	18349290, 18437204, 20453838, 20484103, 20605201, 20699374, 21194473, 21596841, 21791674, 21814516, 22045194, 22087758, 22452962, 22532573, 22666420, 22726230, 22910930, 23577780, 23717390, 24171766, 24414391, 30078824	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Squamous Cell	Squamous cell carcinoma	Pubtator	20885788	Associate	★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	31731190		★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	25315430, 31731190, 31965704	Associate	★☆☆☆☆ Found in Text Mining only
Depressive disorder	Mental Depression	BEFREE	31731190		★☆☆☆☆ Found in Text Mining only
Hereditary Breast and Ovarian Cancer Syndrome	Hereditary breast and ovarian cancer syndrome	Pubtator	22666420	Associate	★☆☆☆☆ Found in Text Mining only
Liver Diseases	Liver disease	Pubtator	31772606	Associate	★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	31731190		★☆☆☆☆ Found in Text Mining only
Mental Depression	Mental Depression	BEFREE	31731190		★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Osteosarcoma	Pubtator	20530236	Associate	★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	28430593	Associate	★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	19767754, 19767755, 21814516, 25315430, 28399564	Associate	★☆☆☆☆ Found in Text Mining only
Pulmonary Disease Chronic Obstructive	Chronic obstructive pulmonary disease	Pubtator	30123065	Associate	★☆☆☆☆ Found in Text Mining only
Urinary Bladder Neoplasms	Urinary bladder neoplasms	Pubtator	21051319	Associate	★☆☆☆☆ Found in Text Mining only
Uterine Cervical Neoplasms	Uterine neoplasm	Pubtator	30018982	Associate	★☆☆☆☆ Found in Text Mining only

Related Genes

No strongly related genes found yet for CASC21.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to CASC21.