CABLES2 (Cdk5 and Abl enzyme substrate 2)

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Gene miRNA Gene ontology Other IDs Protein Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 81928
• Gene name: Cdk5 and Abl enzyme substrate 2
• Gene symbol: CABLES2
• Synonyms (NCBI Gene): C20orf150, dJ908M14.2, ik3-2
• Chromosome: 20
• Chromosome location: 20q13.33

miRNA Show/Hide all (270)

miRTarBase ID	miRNA	Experiments	Reference
MIRT038585	hsa-miR-106b-3p	CLASH	23622248
MIRT857119	hsa-miR-1258	CLIP-seq
MIRT857120	hsa-miR-1273e	CLIP-seq
MIRT857121	hsa-miR-128	CLIP-seq
MIRT857122	hsa-miR-1294	CLIP-seq
MIRT857123	hsa-miR-1297	CLIP-seq
MIRT857124	hsa-miR-1305	CLIP-seq
MIRT857125	hsa-miR-140-5p	CLIP-seq
MIRT857126	hsa-miR-196a	CLIP-seq
MIRT857127	hsa-miR-196b	CLIP-seq
MIRT857128	hsa-miR-216a	CLIP-seq
MIRT857129	hsa-miR-218	CLIP-seq
MIRT857130	hsa-miR-2355-3p	CLIP-seq
MIRT857131	hsa-miR-26a	CLIP-seq
MIRT857132	hsa-miR-26b	CLIP-seq
MIRT857133	hsa-miR-27a	CLIP-seq
MIRT857134	hsa-miR-27b	CLIP-seq
MIRT857135	hsa-miR-298	CLIP-seq
MIRT857136	hsa-miR-3133	CLIP-seq
MIRT857137	hsa-miR-3148	CLIP-seq
MIRT857138	hsa-miR-3157-5p	CLIP-seq
MIRT857139	hsa-miR-3159	CLIP-seq
MIRT857140	hsa-miR-3167	CLIP-seq
MIRT857141	hsa-miR-3173-3p	CLIP-seq
MIRT857142	hsa-miR-3176	CLIP-seq
MIRT857143	hsa-miR-3179	CLIP-seq
MIRT857144	hsa-miR-3185	CLIP-seq
MIRT857145	hsa-miR-3545-5p	CLIP-seq
MIRT857146	hsa-miR-361-5p	CLIP-seq
MIRT857147	hsa-miR-3619-3p	CLIP-seq
MIRT857148	hsa-miR-3654	CLIP-seq
MIRT857149	hsa-miR-377	CLIP-seq
MIRT857150	hsa-miR-3909	CLIP-seq
MIRT857151	hsa-miR-3922-3p	CLIP-seq
MIRT857152	hsa-miR-4318	CLIP-seq
MIRT857153	hsa-miR-4460	CLIP-seq
MIRT857154	hsa-miR-4462	CLIP-seq
MIRT857155	hsa-miR-4465	CLIP-seq
MIRT857156	hsa-miR-4496	CLIP-seq
MIRT857157	hsa-miR-450b-3p	CLIP-seq
MIRT857158	hsa-miR-4536	CLIP-seq
MIRT857159	hsa-miR-4635	CLIP-seq
MIRT857160	hsa-miR-4638-3p	CLIP-seq
MIRT857161	hsa-miR-4640-5p	CLIP-seq
MIRT857162	hsa-miR-4646-3p	CLIP-seq
MIRT857163	hsa-miR-4684-3p	CLIP-seq
MIRT857164	hsa-miR-4691-3p	CLIP-seq
MIRT857165	hsa-miR-4693-5p	CLIP-seq
MIRT857166	hsa-miR-4709-3p	CLIP-seq
MIRT857167	hsa-miR-4719	CLIP-seq
MIRT857168	hsa-miR-4726-5p	CLIP-seq
MIRT857169	hsa-miR-4736	CLIP-seq
MIRT857170	hsa-miR-4747-5p	CLIP-seq
MIRT857171	hsa-miR-4773	CLIP-seq
MIRT857172	hsa-miR-4776-5p	CLIP-seq
MIRT857173	hsa-miR-4779	CLIP-seq
MIRT857174	hsa-miR-498	CLIP-seq
MIRT857175	hsa-miR-499-3p	CLIP-seq
MIRT857176	hsa-miR-499a-3p	CLIP-seq
MIRT857177	hsa-miR-513a-5p	CLIP-seq
MIRT857178	hsa-miR-541	CLIP-seq
MIRT857179	hsa-miR-548ag	CLIP-seq
MIRT857180	hsa-miR-548ai	CLIP-seq
MIRT857181	hsa-miR-569	CLIP-seq
MIRT857182	hsa-miR-582-3p	CLIP-seq
MIRT857183	hsa-miR-591	CLIP-seq
MIRT857184	hsa-miR-595	CLIP-seq
MIRT857185	hsa-miR-636	CLIP-seq
MIRT857186	hsa-miR-651	CLIP-seq
MIRT857187	hsa-miR-654-5p	CLIP-seq
MIRT857188	hsa-miR-657	CLIP-seq
MIRT857189	hsa-miR-659	CLIP-seq
MIRT857190	hsa-miR-676	CLIP-seq
MIRT857191	hsa-miR-765	CLIP-seq
MIRT857192	hsa-miR-769-3p	CLIP-seq
MIRT857193	hsa-miR-876-5p	CLIP-seq
MIRT857194	hsa-miR-892a	CLIP-seq
MIRT857195	hsa-miR-9	CLIP-seq
MIRT857196	hsa-miR-940	CLIP-seq
MIRT1954540	hsa-miR-1197	CLIP-seq
MIRT1954541	hsa-miR-1207-5p	CLIP-seq
MIRT1954542	hsa-miR-125a-3p	CLIP-seq
MIRT1954543	hsa-miR-1265	CLIP-seq
MIRT1954544	hsa-miR-1267	CLIP-seq
MIRT857120	hsa-miR-1273e	CLIP-seq
MIRT857122	hsa-miR-1294	CLIP-seq
MIRT1954545	hsa-miR-1910	CLIP-seq
MIRT1954546	hsa-miR-1976	CLIP-seq
MIRT1954547	hsa-miR-214	CLIP-seq
MIRT857130	hsa-miR-2355-3p	CLIP-seq
MIRT1954548	hsa-miR-2392	CLIP-seq
MIRT1954549	hsa-miR-28-5p	CLIP-seq
MIRT1954550	hsa-miR-29a	CLIP-seq
MIRT1954551	hsa-miR-29b	CLIP-seq
MIRT1954552	hsa-miR-29c	CLIP-seq
MIRT1954553	hsa-miR-3120-5p	CLIP-seq
MIRT1954554	hsa-miR-3130-3p	CLIP-seq
MIRT857136	hsa-miR-3133	CLIP-seq
MIRT1954555	hsa-miR-3134	CLIP-seq
MIRT1954556	hsa-miR-3137	CLIP-seq
MIRT1954557	hsa-miR-3139	CLIP-seq
MIRT1954558	hsa-miR-3171	CLIP-seq
MIRT1954559	hsa-miR-3174	CLIP-seq
MIRT857142	hsa-miR-3176	CLIP-seq
MIRT857143	hsa-miR-3179	CLIP-seq
MIRT1954560	hsa-miR-3189-3p	CLIP-seq
MIRT1954561	hsa-miR-3191	CLIP-seq
MIRT1954562	hsa-miR-3202	CLIP-seq
MIRT1954563	hsa-miR-326	CLIP-seq
MIRT1954564	hsa-miR-330-5p	CLIP-seq
MIRT1954565	hsa-miR-342-5p	CLIP-seq
MIRT1954566	hsa-miR-3614-5p	CLIP-seq
MIRT1954567	hsa-miR-3616-3p	CLIP-seq
MIRT1954568	hsa-miR-3619-5p	CLIP-seq
MIRT1954569	hsa-miR-362-5p	CLIP-seq
MIRT1954570	hsa-miR-3665	CLIP-seq
MIRT1954571	hsa-miR-370	CLIP-seq
MIRT857150	hsa-miR-3909	CLIP-seq
MIRT857151	hsa-miR-3922-3p	CLIP-seq
MIRT1954572	hsa-miR-3934	CLIP-seq
MIRT1954573	hsa-miR-4270	CLIP-seq
MIRT1954574	hsa-miR-4274	CLIP-seq
MIRT1954575	hsa-miR-4276	CLIP-seq
MIRT1954576	hsa-miR-4291	CLIP-seq
MIRT1954577	hsa-miR-4302	CLIP-seq
MIRT1954578	hsa-miR-4422	CLIP-seq
MIRT1954579	hsa-miR-4436b-3p	CLIP-seq
MIRT1954580	hsa-miR-4436b-5p	CLIP-seq
MIRT1954581	hsa-miR-4441	CLIP-seq
MIRT1954582	hsa-miR-4459	CLIP-seq
MIRT857154	hsa-miR-4462	CLIP-seq
MIRT1954583	hsa-miR-4476	CLIP-seq
MIRT1954584	hsa-miR-4481	CLIP-seq
MIRT857157	hsa-miR-450b-3p	CLIP-seq
MIRT1954585	hsa-miR-4533	CLIP-seq
MIRT1954586	hsa-miR-4534	CLIP-seq
MIRT1954587	hsa-miR-455-3p	CLIP-seq
MIRT1954588	hsa-miR-4638-5p	CLIP-seq
MIRT1954589	hsa-miR-4642	CLIP-seq
MIRT857162	hsa-miR-4646-3p	CLIP-seq
MIRT1954590	hsa-miR-4664-5p	CLIP-seq
MIRT1954591	hsa-miR-4666-5p	CLIP-seq
MIRT1954592	hsa-miR-4685-5p	CLIP-seq
MIRT1954593	hsa-miR-4690-5p	CLIP-seq
MIRT1954594	hsa-miR-4708-5p	CLIP-seq
MIRT1954595	hsa-miR-4721	CLIP-seq
MIRT1954596	hsa-miR-4731-5p	CLIP-seq
MIRT1954597	hsa-miR-4734	CLIP-seq
MIRT857169	hsa-miR-4736	CLIP-seq
MIRT1954598	hsa-miR-4745-5p	CLIP-seq
MIRT1954599	hsa-miR-4758-5p	CLIP-seq
MIRT1954600	hsa-miR-4763-3p	CLIP-seq
MIRT1954601	hsa-miR-4768-3p	CLIP-seq
MIRT1954602	hsa-miR-4793-3p	CLIP-seq
MIRT1954603	hsa-miR-500b	CLIP-seq
MIRT1954604	hsa-miR-512-5p	CLIP-seq
MIRT1954605	hsa-miR-516b	CLIP-seq
MIRT857178	hsa-miR-541	CLIP-seq
MIRT1954606	hsa-miR-544	CLIP-seq
MIRT1954607	hsa-miR-621	CLIP-seq
MIRT1954608	hsa-miR-622	CLIP-seq
MIRT1954609	hsa-miR-626	CLIP-seq
MIRT1954610	hsa-miR-637	CLIP-seq
MIRT857187	hsa-miR-654-5p	CLIP-seq
MIRT857189	hsa-miR-659	CLIP-seq
MIRT857190	hsa-miR-676	CLIP-seq
MIRT1954611	hsa-miR-708	CLIP-seq
MIRT1954612	hsa-miR-761	CLIP-seq
MIRT1954613	hsa-miR-764	CLIP-seq
MIRT857191	hsa-miR-765	CLIP-seq
MIRT857192	hsa-miR-769-3p	CLIP-seq
MIRT857195	hsa-miR-9	CLIP-seq
MIRT1954614	hsa-miR-922	CLIP-seq
MIRT1954540	hsa-miR-1197	CLIP-seq
MIRT2192202	hsa-miR-1226	CLIP-seq
MIRT857119	hsa-miR-1258	CLIP-seq
MIRT857120	hsa-miR-1273e	CLIP-seq
MIRT857121	hsa-miR-128	CLIP-seq
MIRT857123	hsa-miR-1297	CLIP-seq
MIRT857124	hsa-miR-1305	CLIP-seq
MIRT1954547	hsa-miR-214	CLIP-seq
MIRT857131	hsa-miR-26a	CLIP-seq
MIRT857132	hsa-miR-26b	CLIP-seq
MIRT857133	hsa-miR-27a	CLIP-seq
MIRT857134	hsa-miR-27b	CLIP-seq
MIRT1954554	hsa-miR-3130-3p	CLIP-seq
MIRT2192203	hsa-miR-3154	CLIP-seq
MIRT857139	hsa-miR-3159	CLIP-seq
MIRT857140	hsa-miR-3167	CLIP-seq
MIRT857142	hsa-miR-3176	CLIP-seq
MIRT857144	hsa-miR-3185	CLIP-seq
MIRT2192204	hsa-miR-320a	CLIP-seq
MIRT2192205	hsa-miR-320b	CLIP-seq
MIRT2192206	hsa-miR-320c	CLIP-seq
MIRT2192207	hsa-miR-320d	CLIP-seq
MIRT1954568	hsa-miR-3619-5p	CLIP-seq
MIRT2192208	hsa-miR-3672	CLIP-seq
MIRT857149	hsa-miR-377	CLIP-seq
MIRT857151	hsa-miR-3922-3p	CLIP-seq
MIRT1954576	hsa-miR-4291	CLIP-seq
MIRT2192209	hsa-miR-4429	CLIP-seq
MIRT857154	hsa-miR-4462	CLIP-seq
MIRT857155	hsa-miR-4465	CLIP-seq
MIRT2192210	hsa-miR-4475	CLIP-seq
MIRT857159	hsa-miR-4635	CLIP-seq
MIRT2192211	hsa-miR-4649-5p	CLIP-seq
MIRT857166	hsa-miR-4709-3p	CLIP-seq
MIRT857167	hsa-miR-4719	CLIP-seq
MIRT857169	hsa-miR-4736	CLIP-seq
MIRT857171	hsa-miR-4773	CLIP-seq
MIRT2192212	hsa-miR-4786-5p	CLIP-seq
MIRT857174	hsa-miR-498	CLIP-seq
MIRT857175	hsa-miR-499-3p	CLIP-seq
MIRT857176	hsa-miR-499a-3p	CLIP-seq
MIRT857177	hsa-miR-513a-5p	CLIP-seq
MIRT857178	hsa-miR-541	CLIP-seq
MIRT857186	hsa-miR-651	CLIP-seq
MIRT857187	hsa-miR-654-5p	CLIP-seq
MIRT1954612	hsa-miR-761	CLIP-seq
MIRT1954613	hsa-miR-764	CLIP-seq
MIRT2192213	hsa-miR-767-5p	CLIP-seq
MIRT2192214	hsa-miR-769-5p	CLIP-seq
MIRT857193	hsa-miR-876-5p	CLIP-seq
MIRT1954614	hsa-miR-922	CLIP-seq
MIRT2192215	hsa-miR-935	CLIP-seq
MIRT1954541	hsa-miR-1207-5p	CLIP-seq
MIRT1954542	hsa-miR-125a-3p	CLIP-seq
MIRT857122	hsa-miR-1294	CLIP-seq
MIRT1954549	hsa-miR-28-5p	CLIP-seq
MIRT1954557	hsa-miR-3139	CLIP-seq
MIRT2192203	hsa-miR-3154	CLIP-seq
MIRT2385437	hsa-miR-3165	CLIP-seq
MIRT857142	hsa-miR-3176	CLIP-seq
MIRT1954566	hsa-miR-3614-5p	CLIP-seq
MIRT857151	hsa-miR-3922-3p	CLIP-seq
MIRT1954572	hsa-miR-3934	CLIP-seq
MIRT1954573	hsa-miR-4270	CLIP-seq
MIRT1954580	hsa-miR-4436b-5p	CLIP-seq
MIRT1954581	hsa-miR-4441	CLIP-seq
MIRT2192210	hsa-miR-4475	CLIP-seq
MIRT857157	hsa-miR-450b-3p	CLIP-seq
MIRT1954588	hsa-miR-4638-5p	CLIP-seq
MIRT857169	hsa-miR-4736	CLIP-seq
MIRT1954600	hsa-miR-4763-3p	CLIP-seq
MIRT1954605	hsa-miR-516b	CLIP-seq
MIRT857178	hsa-miR-541	CLIP-seq
MIRT857187	hsa-miR-654-5p	CLIP-seq
MIRT1954611	hsa-miR-708	CLIP-seq
MIRT1954613	hsa-miR-764	CLIP-seq
MIRT857191	hsa-miR-765	CLIP-seq
MIRT857192	hsa-miR-769-3p	CLIP-seq
MIRT2445999	hsa-miR-1228	CLIP-seq
MIRT2446000	hsa-miR-188-3p	CLIP-seq
MIRT857128	hsa-miR-216a	CLIP-seq
MIRT857130	hsa-miR-2355-3p	CLIP-seq
MIRT2446001	hsa-miR-329	CLIP-seq
MIRT2446002	hsa-miR-362-3p	CLIP-seq
MIRT857150	hsa-miR-3909	CLIP-seq
MIRT2446003	hsa-miR-3925-3p	CLIP-seq
MIRT857162	hsa-miR-4646-3p	CLIP-seq
MIRT2446004	hsa-miR-4691-5p	CLIP-seq
MIRT2446005	hsa-miR-4722-3p	CLIP-seq
MIRT2446006	hsa-miR-4769-3p	CLIP-seq
MIRT2446007	hsa-miR-4793-5p	CLIP-seq
MIRT1954608	hsa-miR-622	CLIP-seq
MIRT857189	hsa-miR-659	CLIP-seq
MIRT857190	hsa-miR-676	CLIP-seq
MIRT857195	hsa-miR-9	CLIP-seq
MIRT857144	hsa-miR-3185	CLIP-seq
MIRT857171	hsa-miR-4773	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005829	Component	Cytosol	IEA
GO:0051301	Process	Cell division	IEA
GO:0051726	Process	Regulation of cell cycle	IEA

Other IDs

• MIM: 618772
• HGNC: 16143
• e!Ensembl: ENSG00000149679

Protein

• UniProt ID: Q9BTV7
• Protein name: CDK5 and ABL1 enzyme substrate 2 (Interactor with CDK3 2) (Ik3-2)
• Protein function: Unknown. Probably involved in G1-S cell cycle transition.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00134	Cyclin_N	330 → 461	Cyclin, N-terminal domain	Domain

• Sequence:

  MAAAAAGGAPGPAPGPAGPPPPAAPTSAARAPPQALRRRGDSRRRQAALFFLNNISLDGR
  PPSLGPGGEKPPPPPAEAREPPAPPPPEPPTGLPARTPAPQGLLSPTQVPTGLGLDGQRQ
  RKRVTSQRCSLEFLEDAVGCAPAQRTKHTSGSPRHKGLKKTHFIKNMRQYDTRNSRIVLI
  CAKRSLCAAFSVLPYGEGLRISDLRVDSQKQRHPSGGVSVSSEMVFELEGVELGADGKVV
  SYAKFLYPTNALVTHKSDSHGLLPTPRPSVPRTLPGSRHKPAPTKSAPASTELGSDVGDT
  LEYNPNLLDDPQWPCGKHKRVLIFASYMTTVIEYVKPSDLKKDMNETFREKFPHVKLTLS
  KIRSLKREMRSLSEECSLEPVTVAMAYVYFEKLVLQGKLSKQNRKLCAGACVLLAAKISS
  DLRKSGVTQLIDKLEERFRFNRRDLIGFEFTVLVALELALYLPENQVLPHYRRLTQQF

• Sequence length: 478

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations Show/Hide Unknown Diseases (6)
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
ALZHEIMER DISEASE	—	GWAS catalog	39998322	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BENIGN NEOPLASM	—	GWAS catalog	39024449	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLOR VISION DISORDER	—	GWAS catalog	37359372	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLORECTAL CANCER	—	GWAS catalog	24737748, 25990418, 29471430, 29917119, 34594039	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
EBV-positive nodal T- and NK-cell lymphoma	Likely benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INSOMNIA	—	GWAS catalog	35835914	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining Show/Hide Text Mining Associations (9)
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Adenocarcinoma of large intestine	Colorectal Cancer	GWASCAT_DG	24737748, 25990418, 29917119		★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	33058866	Associate	★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	GWASDB_DG	24737748		★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	GWASCAT_DG	24737748, 25990418, 29917119		★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal Neoplasms	GWASCAT_DG	24737748, 25990418, 29917119		★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	28506205, 33058866	Associate	★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of large intestine	Colorectal Neoplasms	GWASCAT_DG	24737748, 25990418, 29917119		★☆☆☆☆ Found in Text Mining only
Malignant tumor of colon	Colonic Neoplasms	GWASCAT_DG	24737748, 25990418, 29917119		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	28506205		★☆☆☆☆ Found in Text Mining only

Related Genes

No strongly related genes found yet for CABLES2.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to CABLES2.