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Gene Gene information from NCBI Gene database.
Entrez ID 387263
Gene name Chromosome 6 open reading frame 120
Gene symbol C6orf120
Synonyms (NCBI Gene)
-
Chromosome 6
Chromosome location 6q27
Summary This gene encodes a conserved, N-glycosylated protein that likely functions in the cellular response to endoplasmic reticulum stress. This protein is able to induce apoptosis in vitro in CD4+ T-cells. Alternative splicing results in multiple transcript va
miRNA miRNA information provided by mirtarbase database.
671 Show/Hide all (671)
miRTarBase ID miRNA Experiments Reference
MIRT028723 hsa-miR-27a-3p Sequencing 20371350
MIRT044361 hsa-miR-106b-5p CLASH 23622248
MIRT039225 hsa-miR-454-3p CLASH 23622248
MIRT503076 hsa-miR-4714-3p PAR-CLIP 24398324
MIRT218305 hsa-miR-5681a PAR-CLIP 24398324
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
5
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 28514442, 33961781
GO:0005576 Component Extracellular region IEA
GO:0005576 Component Extracellular region TAS
GO:0006915 Process Apoptotic process IEA
GO:0035578 Component Azurophil granule lumen TAS
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
616987 21247 ENSG00000185127
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q7Z4R8
Protein name UPF0669 protein C6orf120
Protein function May be involved in induction of apoptosis in CD4(+) T-cells, but not CD8(+) T-cells or hepatocytes.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF17065 UPF0669 7 → 191 Putative cytokine, C6ORF120 Family
Tissue specificity TISSUE SPECIFICITY: Mainly expressed in hepatocytes and some weak expression in germinal center cells of lymph nodes. {ECO:0000269|PubMed:22340178}.
Sequence
Sequence length 191
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Reactome Pathway
Neutrophil degranulation