BYSL (bystin like)

Download as csv Download as pdf

Log in to bookmark this gene

Bookmark This Gene

Title Project / Tag (optional) Note (optional)

Cancel Save

On this page

Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 705
• Gene name: Bystin like
• Gene symbol: BYSL
• Synonyms (NCBI Gene): BYSTIN, Enp1
• Chromosome: 6
• Chromosome location: 6p21.1
• Summary: Bystin is expressed as a 2-kb major transcript and a 3.6-kb minor transcript in SNG-M cells and in human trophoblastic teratocarcinoma HT-H cells. Protein binding assays determined that bystin binds directly to trophinin and tastin, and that binding is en

miRNA Show/Hide all (147)

miRTarBase ID	miRNA	Experiments	Reference
MIRT022085	hsa-miR-128-3p	Sequencing	20371350
MIRT026739	hsa-miR-192-5p	Sequencing	20371350
MIRT031885	hsa-miR-16-5p	Proteomics	18668040
MIRT044510	hsa-miR-320a	CLASH	23622248
MIRT043945	hsa-miR-378a-3p	CLASH	23622248
MIRT827831	hsa-miR-128	CLIP-seq
MIRT827832	hsa-miR-146b-3p	CLIP-seq
MIRT827833	hsa-miR-193a-5p	CLIP-seq
MIRT827834	hsa-miR-3120-5p	CLIP-seq
MIRT827835	hsa-miR-3152-5p	CLIP-seq
MIRT827836	hsa-miR-3157-5p	CLIP-seq
MIRT827837	hsa-miR-3173-5p	CLIP-seq
MIRT827838	hsa-miR-320b	CLIP-seq
MIRT827839	hsa-miR-320c	CLIP-seq
MIRT827840	hsa-miR-320d	CLIP-seq
MIRT827841	hsa-miR-3661	CLIP-seq
MIRT827842	hsa-miR-4429	CLIP-seq
MIRT827843	hsa-miR-4691-3p	CLIP-seq
MIRT827844	hsa-miR-4774-3p	CLIP-seq
MIRT827845	hsa-miR-511	CLIP-seq
MIRT827846	hsa-miR-631	CLIP-seq
MIRT827847	hsa-miR-642b	CLIP-seq
MIRT827848	hsa-miR-668	CLIP-seq
MIRT827849	hsa-miR-874	CLIP-seq
MIRT1944935	hsa-miR-1207-3p	CLIP-seq
MIRT1944936	hsa-miR-1228	CLIP-seq
MIRT1944937	hsa-miR-3144-5p	CLIP-seq
MIRT1944938	hsa-miR-3146	CLIP-seq
MIRT1944939	hsa-miR-3191	CLIP-seq
MIRT1944940	hsa-miR-3199	CLIP-seq
MIRT1944941	hsa-miR-342-3p	CLIP-seq
MIRT1944942	hsa-miR-3680	CLIP-seq
MIRT1944943	hsa-miR-4323	CLIP-seq
MIRT1944944	hsa-miR-4515	CLIP-seq
MIRT1944945	hsa-miR-4646-5p	CLIP-seq
MIRT1944946	hsa-miR-4652-5p	CLIP-seq
MIRT1944947	hsa-miR-4667-5p	CLIP-seq
MIRT1944948	hsa-miR-4700-5p	CLIP-seq
MIRT1944949	hsa-miR-4715-5p	CLIP-seq
MIRT1944950	hsa-miR-4731-5p	CLIP-seq
MIRT1944951	hsa-miR-4798-3p	CLIP-seq
MIRT1944952	hsa-miR-513c	CLIP-seq
MIRT1944953	hsa-miR-514b-5p	CLIP-seq
MIRT1944954	hsa-miR-548k	CLIP-seq
MIRT1944955	hsa-miR-548n	CLIP-seq
MIRT1944956	hsa-miR-621	CLIP-seq
MIRT827847	hsa-miR-642b	CLIP-seq
MIRT1944935	hsa-miR-1207-3p	CLIP-seq
MIRT1944936	hsa-miR-1228	CLIP-seq
MIRT1944937	hsa-miR-3144-5p	CLIP-seq
MIRT1944938	hsa-miR-3146	CLIP-seq
MIRT1944939	hsa-miR-3191	CLIP-seq
MIRT1944940	hsa-miR-3199	CLIP-seq
MIRT1944941	hsa-miR-342-3p	CLIP-seq
MIRT1944942	hsa-miR-3680	CLIP-seq
MIRT1944943	hsa-miR-4323	CLIP-seq
MIRT1944944	hsa-miR-4515	CLIP-seq
MIRT1944945	hsa-miR-4646-5p	CLIP-seq
MIRT1944946	hsa-miR-4652-5p	CLIP-seq
MIRT1944947	hsa-miR-4667-5p	CLIP-seq
MIRT1944948	hsa-miR-4700-5p	CLIP-seq
MIRT1944950	hsa-miR-4731-5p	CLIP-seq
MIRT1944951	hsa-miR-4798-3p	CLIP-seq
MIRT1944954	hsa-miR-548k	CLIP-seq
MIRT1944955	hsa-miR-548n	CLIP-seq
MIRT1944956	hsa-miR-621	CLIP-seq
MIRT827847	hsa-miR-642b	CLIP-seq
MIRT1944935	hsa-miR-1207-3p	CLIP-seq
MIRT1944936	hsa-miR-1228	CLIP-seq
MIRT1944937	hsa-miR-3144-5p	CLIP-seq
MIRT1944938	hsa-miR-3146	CLIP-seq
MIRT1944939	hsa-miR-3191	CLIP-seq
MIRT1944940	hsa-miR-3199	CLIP-seq
MIRT827838	hsa-miR-320b	CLIP-seq
MIRT827839	hsa-miR-320c	CLIP-seq
MIRT827840	hsa-miR-320d	CLIP-seq
MIRT1944941	hsa-miR-342-3p	CLIP-seq
MIRT1944942	hsa-miR-3680	CLIP-seq
MIRT1944943	hsa-miR-4323	CLIP-seq
MIRT827842	hsa-miR-4429	CLIP-seq
MIRT1944944	hsa-miR-4515	CLIP-seq
MIRT1944945	hsa-miR-4646-5p	CLIP-seq
MIRT1944946	hsa-miR-4652-5p	CLIP-seq
MIRT1944947	hsa-miR-4667-5p	CLIP-seq
MIRT1944948	hsa-miR-4700-5p	CLIP-seq
MIRT1944950	hsa-miR-4731-5p	CLIP-seq
MIRT1944951	hsa-miR-4798-3p	CLIP-seq
MIRT1944956	hsa-miR-621	CLIP-seq
MIRT2444960	hsa-miR-3187-3p	CLIP-seq
MIRT2444961	hsa-miR-3667-3p	CLIP-seq
MIRT2444962	hsa-miR-4435	CLIP-seq
MIRT2444963	hsa-miR-4436a	CLIP-seq
MIRT2444964	hsa-miR-4701-5p	CLIP-seq
MIRT2444965	hsa-miR-548s	CLIP-seq
MIRT2444966	hsa-miR-588	CLIP-seq
MIRT1944935	hsa-miR-1207-3p	CLIP-seq
MIRT1944936	hsa-miR-1228	CLIP-seq
MIRT1944937	hsa-miR-3144-5p	CLIP-seq
MIRT1944938	hsa-miR-3146	CLIP-seq
MIRT1944939	hsa-miR-3191	CLIP-seq
MIRT1944940	hsa-miR-3199	CLIP-seq
MIRT1944941	hsa-miR-342-3p	CLIP-seq
MIRT1944942	hsa-miR-3680	CLIP-seq
MIRT1944943	hsa-miR-4323	CLIP-seq
MIRT2487122	hsa-miR-4330	CLIP-seq
MIRT2487123	hsa-miR-4512	CLIP-seq
MIRT1944944	hsa-miR-4515	CLIP-seq
MIRT1944945	hsa-miR-4646-5p	CLIP-seq
MIRT1944946	hsa-miR-4652-5p	CLIP-seq
MIRT1944947	hsa-miR-4667-5p	CLIP-seq
MIRT1944948	hsa-miR-4700-5p	CLIP-seq
MIRT1944949	hsa-miR-4715-5p	CLIP-seq
MIRT1944950	hsa-miR-4731-5p	CLIP-seq
MIRT1944951	hsa-miR-4798-3p	CLIP-seq
MIRT1944952	hsa-miR-513c	CLIP-seq
MIRT1944953	hsa-miR-514b-5p	CLIP-seq
MIRT1944954	hsa-miR-548k	CLIP-seq
MIRT1944955	hsa-miR-548n	CLIP-seq
MIRT1944956	hsa-miR-621	CLIP-seq
MIRT827847	hsa-miR-642b	CLIP-seq
MIRT2487124	hsa-miR-7	CLIP-seq
MIRT2487125	hsa-miR-760	CLIP-seq
MIRT1944935	hsa-miR-1207-3p	CLIP-seq
MIRT1944936	hsa-miR-1228	CLIP-seq
MIRT1944937	hsa-miR-3144-5p	CLIP-seq
MIRT1944938	hsa-miR-3146	CLIP-seq
MIRT1944939	hsa-miR-3191	CLIP-seq
MIRT1944940	hsa-miR-3199	CLIP-seq
MIRT1944941	hsa-miR-342-3p	CLIP-seq
MIRT1944942	hsa-miR-3680	CLIP-seq
MIRT1944943	hsa-miR-4323	CLIP-seq
MIRT2487122	hsa-miR-4330	CLIP-seq
MIRT1944944	hsa-miR-4515	CLIP-seq
MIRT1944945	hsa-miR-4646-5p	CLIP-seq
MIRT1944946	hsa-miR-4652-5p	CLIP-seq
MIRT1944947	hsa-miR-4667-5p	CLIP-seq
MIRT1944948	hsa-miR-4700-5p	CLIP-seq
MIRT1944949	hsa-miR-4715-5p	CLIP-seq
MIRT1944950	hsa-miR-4731-5p	CLIP-seq
MIRT1944951	hsa-miR-4798-3p	CLIP-seq
MIRT1944952	hsa-miR-513c	CLIP-seq
MIRT1944953	hsa-miR-514b-5p	CLIP-seq
MIRT1944954	hsa-miR-548k	CLIP-seq
MIRT1944955	hsa-miR-548n	CLIP-seq
MIRT1944956	hsa-miR-621	CLIP-seq
MIRT827847	hsa-miR-642b	CLIP-seq
MIRT2487125	hsa-miR-760	CLIP-seq

Gene ontology (GO) Show/Hide all (26)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000462	Process	Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	IEA
GO:0001701	Process	In utero embryonic development	IEA
GO:0001825	Process	Blastocyst formation	IEA
GO:0001829	Process	Trophectodermal cell differentiation	IEA
GO:0003723	Function	RNA binding	HDA	22658674
GO:0005515	Function	Protein binding	IPI	9560222, 16189514, 16713569, 17360433, 21516116, 25416956, 27107012, 28514442, 30886144, 31515488, 32296183, 33961781, 35271311, 36217029, 36217030
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005694	Component	Chromosome	IDA
GO:0005730	Component	Nucleolus	IBA
GO:0005730	Component	Nucleolus	IDA	26711351
GO:0005730	Component	Nucleolus	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	TAS	9560222
GO:0005829	Component	Cytosol	TAS
GO:0006364	Process	RRNA processing	IBA
GO:0016020	Component	Membrane	HDA	19946888
GO:0030515	Function	SnoRNA binding	IBA
GO:0030688	Component	Preribosome, small subunit precursor	IBA
GO:0042254	Process	Ribosome biogenesis	IEA
GO:0042254	Process	Ribosome biogenesis	ISS
GO:0045177	Component	Apical part of cell	IEA
GO:0072089	Process	Stem cell proliferation	IEA
GO:1904749	Process	Regulation of protein localization to nucleolus	ISS

Other IDs

• MIM: 603871
• HGNC: 1157
• e!Ensembl: ENSG00000112578

Protein

• UniProt ID: Q13895
• Protein name: Bystin
• Protein function: Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos. {ECO:0000269|PubMed:17360433, ECO:0000269|PubMe
• PDB: 6G18 , 6G4S , 6G4W , 7WTT , 7WTU , 7WTV , 7WTW , 7WTX , 7WTZ , 7WU0
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF05291	Bystin	141 → 431	Bystin	Family

• Tissue specificity: TISSUE SPECIFICITY: Found in the placenta from the sixth week of pregnancy. Was localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface. After week 10, the level decrea
• Sequence:

  MPKFKAARGVGGQEKHAPLADQILAGNAVRAGVREKRRGRGTGEAEEEYVGPRLSRRILQ
  QARQQQEELEAEHGTGDKPAAPRERTTRLGPRMPQDGSDDEDEEWPTLEKAATMTAAGHH
  AEVVVDPEDERAIEMFMNKNPPARRTLADIIMEKLTEKQTEVETVMSEVSGFPMPQLDPR
  VLEVYRGVREVLSKYRSGKLPKAFKIIPALSNWEQILYVTEPEAWTAAAMYQATRIFASN
  LKERMAQRFYNLVLLPRVRDDVAEYKRLNFHLYMALKKALFKPGAWFKGILIPLCESGTC
  TLREAIIVGSIITKCSIPVLHSSAAMLKIAEMEYSGANSIFLRLLLDKKYALPYRVLDAL
  VFHFLGFRTEKRELPVLWHQCLLTLVQRYKADLATDQKEALLELLRLQPHPQLSPEIRRE
  LQSAVPRDVEDVPITVE

• Sequence length: 437

Pathways

Reactome Pathway:

Major pathway of rRNA processing in the nucleolus and cytosol

Related Genes

No strongly related genes found yet for BYSL.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to BYSL.